NorthWest Biotherapeutics Inc (NWBO)

[Doktornolittle]

Rene: I don't know about the stats for compassionate use in Israel, and it bothers me too...

but Linda Powers did state that they had seen an 80% response rate for DCVax-L and she stated a large number for cases without a negative side effect. Not sure if she stated the large number as relating to the 80% response rate. I would have to read that carefully.

Further, there are other DCVax studies out there... and would need to check the detail of the wording to be sure she was not including those. Seems unlikely, but it should be looked at.

If the 80% response rate was for that large number of patients stated, and if those were all for Northwest's DCVax-L, then they must be from compassionate use. They have that in the US as well as Israel, don't they? But likely it would include Israel.

What does response rate mean in that statement? Not sure. Others will know. Probably tumor shrinkage. I don't think the compassionate use is limited to GBM, at least in Israel, but not sure. That one Israeli patient interviewed had GMB metastasized from colon cancer, or was it the other way around?

Anyway, a framework to begin to nail this down. But I never heard and stats specifically stated about compassionate use in Israel or anywhere else.