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Threshold Pharmaceuticals Inc. (THLD)

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Last Post: 2/12/2015 1:53:16 PM - Followers: 122 - Board type: Free - Posts Today: 0

Threshold Pharmaceuticals, Inc (THLD) 






Company Address:
1300 Seaport Boulevard, Suite 500

Redwood City, CA 94063



CIK:  0001183765

is a biotechnology company focused on the discovery and development of therapeutics based on Tumor Hypoxia, a powerful scientific platform that offers broad potential to treat most solid tumors. By selectively targeting tumor cells, we are building a pipeline of drugs that hold promise to be more effective and less toxic to healthy tissues than conventional drugs.


Management:  http://www.thresholdpharm.com/sec/management





Clinical Pipeline:

Product Pipeline: 
TH-302 is a hypoxia-activated prodrug (HAP) for the potential treatment of solid tumors. TH-302, which was discovered at Threshold, is a novel drug candidate that is activated under the metabolic conditions typical of cancer cells. We filed an IND (Investigational New Drug) with the FDA in April 2007 and started a Phase 1 clinical trial in July 2007. We initiated a second clinical trial of TH-302 in August 2008. This Phase 1/2 clinical trial is also focused on treating solid tumors.

Glufosfamide has been investigated for the potential treatment of pancreatic cancer, small cell lung cancer, platinum-resistant ovarian cancer and advanced soft tissue sarcoma. The soft tissue sarcoma trial provided evidence of clinical activity. Additionally, in a phase 2 clinical trial of glufosfamide in combination with gemcitabine for the treatment of advanced pancreatic cancer, the data indicated that glufosfamide plus gemcitabine may benefit patients with chemotherapy naive pancreatic cancer. The Company will be seeking a partner to continue development of glufosfamide in cancer.

2-Deoxyglucose, or 2DG, for the treatment of solid tumors, has been evaluated in a Phase 1 clinical trial alone and in combination with Taxotere.


Recent News: 




Filings:  http://www.sec.gov/cgi-bin/browse-edgar?company=&match=&CIK=0001183765&filenum=&State=&Country=&SIC=&owner=exclude&Find=Find+Companies&action=getcompany




Transfer Agent:
Mellon Investor Services LLC
85 Challenger Road
Ridgefield Park, NJ 07660

BNYMellon Shareowner Services


Share Structure:

Outstanding Shares

33,702,242 as of Oct 31, 2010


Authorized Shares

150,000,000 as of Sep 30, 2010


Preferred Shares Authorized

2,000,000 as of Sep 30, 2010


No Preferreds Issued or Outstanding as of Sep 30, 2010





Investor Relations:
Denise T. Powell
Threshold Pharmaceuticals






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Current Price
Bid Ask Day's Range
Option Chain for THLD
THLD News: Securities Registration: Employee Benefit Plan (s-8) 03/03/2015 05:24:30 PM
THLD News: Annual Report (10-k) 03/03/2015 05:11:02 PM
THLD News: Current Report Filing (8-k) 03/03/2015 07:16:13 AM
THLD News: Threshold Pharmaceuticals beats by $0.01, misses on revenue 03/03/2015 07:10:22 AM
#2486   Nice Chart!!! B/O soon? No worries 02/12/15 01:53:16 PM
#2485   I think they're waiting on trial results. Of Youlie 02/11/15 08:40:25 PM
#2484   I'm long on THLD mainly because all of moneycents 02/11/15 09:19:14 AM
#2483   $THLD H.C. Wainwright Maintains Buy On Threshold Pharmaceuticals maytepper 12/08/14 04:51:28 PM
#2482   $THLD Cantor Fitzgerald Reaffirms Buy On Threshold Pharmaceuticals maytepper 11/18/14 03:42:30 PM
#2481   This fast track designation came out of no null 11/14/14 12:42:45 PM
#2480   it's looking that way....I have been dollar cost averaging..... scstocks 11/14/14 11:41:48 AM
#2479   No I did not. I had lowered my null 11/14/14 11:36:47 AM
#2478   H.C. Wainwright Reiterates Buy On Threshold Pharmaceuticals, Sees maytepper 11/13/14 12:47:19 PM
#2477   from today's 8k: scstocks 11/12/14 12:05:35 PM
#2476   hope you were able to get some of scstocks 11/11/14 04:12:38 PM
#2475   ===We believe that our cash, cash equivalents and scstocks 11/03/14 01:04:46 PM
#2474   This will definitely come into favor mid next null 10/22/14 04:26:31 PM
#2473   Tired of holding and watching it go down moneycents 10/21/14 08:13:14 PM
#2472   Hey I still own some this and looked umiak 10/14/14 06:30:33 PM
#2471   Chart looking much better, looks like we have shark44 10/14/14 02:23:04 PM
#2470   Hope to load up in $2.50s range here. null 10/10/14 12:33:41 PM
#2469   THLD CHART was looking to sell $30,000,000 worth bUrRpPPP! 10/10/14 11:25:58 AM
#2468   Sub two weeks to big news. Fingers crossed faraifarai 09/16/14 08:28:22 PM
#2467   On watch for tomorrow... PROPHETABLE 09/08/14 11:42:40 PM
#2466   Guessing Leerink Summit Sept 17 18 in Napa PJO 08/22/14 03:01:57 PM
#2465   DD ? PJO 08/22/14 02:59:08 PM
#2464   True, but then most health care stocks are! Ratan09 08/14/14 11:29:11 AM
#2463   This co. price swings are so hard to jcJet12 08/12/14 04:37:34 PM
#2462   Loaded 5K shares @4.20. Ratan09 08/12/14 01:42:36 PM
#2461   Threshold Pharmaceuticals just filed a prospectus, suggesting it $$$eeker 08/01/14 09:39:02 AM
#2460   With the Market down 311 points today, THLD moneycents 07/31/14 07:01:17 PM
#2459   Looks like a small block at $4.25, probably porgyrusty 07/22/14 12:03:13 PM
#2458   Thank you. bluemonstr 07/21/14 05:05:31 PM
#2457   The target is supposed to be the price LasNubes 07/21/14 01:50:20 PM
#2456   Yahoo just increased Price Target to $14.17 from bluemonstr 07/21/14 01:31:52 PM
#2455   I hope those targets are correct. I added LasNubes 07/20/14 08:34:28 AM
#2454   Yahoo just increased Price Target to $14.17 from moneycents 07/18/14 10:13:49 PM
#2453   then why is it staying at 3-4 range? accumulation? vip1999 07/12/14 04:43:57 AM
#2452   Latest Price Targets for THLD. Yahoo $12.90; Investors.com moneycents 07/11/14 10:04:02 PM
#2451   Just started a position here at $4.15 LasNubes 07/07/14 11:24:18 AM
#2450   wow, this is what it is like with vip1999 05/19/14 10:53:11 PM
#2449   Ha. Ignore me! This was intended for another faraifarai 03/11/14 08:34:36 AM
#2448   My take is similar. Buy now, pretend you faraifarai 03/11/14 08:29:10 AM
#2447   sorry, I can't PM. I held it vip1999 03/11/14 04:01:47 AM
#2446   I think this will become a midcap stock vip1999 03/10/14 02:10:32 PM
#2445   I am considering buying this stock. What's mercedes49 03/10/14 11:07:06 AM
#2444   What happened with BR? rgqui2000 02/05/14 08:56:06 AM
#2443   should be above $5 by now. vip1999 12/30/13 07:31:31 AM
#2442   THLD 4.68 announces target enrollment [SMART MONEY] 12/30/13 07:01:37 AM
#2441   How might CYTR's success in Sarcoma affect THLD? dia76ca 12/16/13 04:16:00 PM
#2440   I have been watching that one, now it binchey 11/28/13 05:25:09 AM
#2439   THLD @ Stockcharts Investor100 10/21/13 08:39:47 PM
#2438   7:01AM Threshold Pharma announces early clinical data for surf1944 10/21/13 03:19:32 PM
#2437   Very nice article on THLD and Sarcoma trials jcJet12 09/27/13 12:18:42 PM