This iBox Last Updated on 05/12/2008
Cortex Business summary – from company website:
Cortex Pharmaceuticals, Inc. is a biopharmaceutical company focused on the discovery, development and commercialization of novel small molecule drugs called AMPAKINE molecules targeted towards human central nervous system diseases. AMPAKINE molecules represent a new approach to treating psychiatric disorders, neurological diseases and brain mediated breathing disorders. AMPAKINE compounds are small drug-like molecules that positively modulate the AMPA-type glutamate receptor complex, amplifying the effect of the most prominent brain neurotransmitter, glutamate leading to excitation of multiple brain circuits that effect learning and memory, attention, and a unique brain stem structure thought to be responsible for maintaining breathing.
An 30 minute company webcast presentation (with slides) from 2/19/2008 is available here: http://www.wsw.com/webcast/roth16/cor/
Ampakines have the potential to address indications that range from orphan indications to $1 Billion plus sized markets:
Alzheimer’s Disease
Schizophrenia
Depression
ADHD
Autism
Parkinson’s Disease
Respiratory Depression
MCI (Mild Cognitive Impairment)
Substance Abuse
Memory Loss due to ECT (Electroconvulsive therapy)
Anxiety Disorders
Fragile X
SCI (Spinal Cord Injury)
Narcolepsy
EDS (Excessive Daytime Sleepiness)
Rett's Syndrome
CABGS (Coronary Artery Bypass Graft Surgery)
Stroke
Seizure
TBI (Traumatic Brain Injury)
Huntington's Disease
ALS (Amyotrophic Lateral Sclerosis, aka Lou Gehrig's Disease)
To learn more about Cortex and Ampakines, visit Cortex's website: http://cortexpharm.com/
Good luck to Cortex and COR investors – clinical success for Ampakines will mean a vastly improved quality of life for millions of patients as well as significant financial rewards for Cortex investors... Aiming4.
Cortex-related links:
Cortex company website:
http://www.cortexpharm.com/
Dr. Tracy (Neuroinvestment) Cortex commentary:
www.neuroinvestment.com/NewComCortex.html
Worldwide Patent database: Ampa related patents:
http://v3.espacenet.com/results?TI=ampa&sf=a&DB=EPODOC&PGS=10&CY=ep&LG=en&ST...
Information website for Ampakines (not an official Cortex company website):
http://www.ampakines.org/index.htm
Wikipedia entry for Ampakine:
http://en.wikipedia.org/wiki/Ampakines
Historical Summary of Cortex's Press Releases and articles:
http://links.biospace.com/news_company.cfm?CompanyID=1351&SR=1
BarChart.com COR trend indicators snapshot:
http://quotes.barchart.com/texpert.asp?sym=cor
Thompson I-Watch
Institutional vs. Retail
http://iwp.thomsonfn.com/tfspro/iwatch/cgi-bin/iw_ticker?ticker=cor
COR Insider Trading info:
http://moneycentral.msn.com/investor/invsub/insider/trans.asp?Symbol=cor
COR Historical COR stock prices:
Select date range at the top of page first...
http://stockmarket.businessweek.com/stocks/historical_quote.html?NOTATION=7879629
Research Paper abstracts for "Ampakines":
http://www.neurotransmitter.net/ampakines.html
TURNS website (Trialing Ampakine Org 24448 for enhancing neurocognition in patients with schizophrenia):
http://www.turns.ucla.edu/index.shtml
Cortex Message Boards
Erbse's German Cortex Message Board:
http://www.erbse.vm-elsig.de/form/base/YaBB.pl?catselect=Cortex_Pharmaceuticals
Yahoo Cortex Message Board:
http://messages.finance.yahoo.com/mb/COR
Silicon Investor Cortex Message Board:
http://www.siliconinvestor.com/subject.aspx?subjectid=3299
Investor's Village Cortex Message Board:
http://www.investorvillage.com/smbd.asp?mb=927&pt=m
Yahoo Cortex Investor's Forum Group (Inactive):
http://finance.groups.yahoo.com/group/CortexInvestorsForum/
Raging Bull Cortex Message Board (Inactive):
http://ragingbull.quote.com/mboard/boards.cgi?board=CORX
AMEX/COR Options Trading Info:
http://www.nasdaq.com/aspxcontent/options.aspx?symbol=COR&symbol=&symbol=&symbol=&sy...
AMEX/COR Pre-Market trading:
http://quotes.nasdaq.com/aspxcontent/ExtendedTradingTrades.aspx?mode=&page=afterhours&symbol...
AMEX/COR After Hours trading:
http://quotes.nasdaq.com/aspxcontent/ExtendedTradingTrades.aspx?page=afterhours&mkttype=after&am...
AMEX/COR Short Interest:
http://www.nasdaq.com/asp/quotes_full.asp?mode=&kind=shortint&symbol=&symbol=COR&sym...
AMEX/COR Institutional Holdings:
http://www.nasdaq.com/asp/holdings.asp?mode=&kind=&symbol=COR&symbol=&symbol=&sy...
AMEX/COR Insider Holdings:
http://www.nasdaq.com/asp/Holdings.asp?mode=&kind=&symbol=COR&symbol=&symbol=&sy...
Cortex SEC filings - from Yahoo:
http://finance.yahoo.com/q/sec?s=cor
Cortex SEC filings - from Edgar.com:
http://edgar.brand.edgar-online.com/default.aspx?sym=cor
Cortex SEC filings - from SecInfo.com:
http://www.secinfo.com/$/SEC/Registrant.asp?CIK=849636
Schering-Plough website - Cortex partner (purchased Organon 2007/03/12):
http://www.schering-plough.com/schering_plough/index.jsp
Schering/Organon Phase II Trial (in progress? no longer recruiting as of 2/2007): Org 24448 to Treat Depression:
http://www.clinicaltrials.gov/ct/show/NCT00113022?order=1
Schering/Organon Phase II Trial (not yet recruiting as of 1/2007): Org 24448 for Cognitive Deficits in Schizophrenia:
http://www.clinicaltrials.gov/ct/show/NCT00425815?order=1
Schering/Organon Phase II Trial (recruiting as of 6/2006): Randomized, Placebo-Controlled Trial of Org 24448 in Major Depressive Disorder:
http://www.clinicaltrials.gov/ct/show/NCT00262665?order=2
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