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VistaGen Therapeutics, Inc. (VTGN)

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VistaGen Therapeutics, Inc. (VSTA) 
www.VistaGen.com
 

VistaGen Investor Summary: http://vsta.missionir.com/vsta/

VistaGen Interview with MissionIR: http://vsta.missionir.com/vsta/interview.html

VistaGen 2014 10-K   http://biz.yahoo.com/e/140625/vsta10-k.html


Company Profile

VistaGen Therapeutics, Inc. is a biotechnology company applying stem cell technology for drug rescue and cell therapy. Drug rescue combines human stem cell technology with modern medicinal chemistry to generate new chemical variants ("drug rescue variants") of once-promising drug candidates that have been discontinued during late-stage preclinical development due to heart or liver safety concerns. VistaGen also focuses on cell therapy, or regenerative medicine, which includes repairing, replacing or restoring damaged tissues or organs.

VistaGen's versatile stem cell technology platform, Human Clinical Trials in a Test Tube™, has been developed to provide clinically relevant predictions of potential heart and liver toxicity of promising new drug candidates long before they are ever tested on humans.

By more closely approximating human biology than conventional animal studies and other nonclinical techniques and technologies currently used in drug development, VistaGen's human stem cell-based bioassay systems can improve the predictability of the drug development cycle and lower the cost of new drug research and development by identifying product failures earlier in the cost curve. According to the Food and Drug Administration even only a ten percent improvement in predicting failure before clinical trials could save $100 million in development costs, which savings ultimately could be passed on to patients.

Using mature human heart cells produced from stem cells, VistaGen has developed and internally validated CardioSafe 3D™, a novel three-dimensional (3D) bioassay system for predicting the in vivo cardiac effects of new drug candidates before they are tested in humans. VistaGen is now focused on using CardioSafe 3D™ to generate up to two new, safer small molecule drug rescue variants every twelve to eighteen months. VistaGen anticipates that these drug rescue variants will be modified versions of once-promising new drug candidates that have been discontinued by pharmaceutical companies and academic research institutions because of heart toxicity concerns, despite substantial prior investment and positive efficacy data demonstrating their potential therapeutic and commercial benefits. In most cases, VistaGen plans to license or sell its new, safer drug rescue variants in strategic partnering arrangements with global pharmaceutical companies, arrangements providing VistaGen with both near term and downstream milestone payments and economic participation rights but without future development cost obligations.

AV-101, VistaGen's lead small molecule prodrug candidate, has successfully completed Phase I clinical development in the U.S. for treatment of neuropathic pain, a serious and chronic condition affecting millions of people worldwide, depression, and other neurological diseases and conditions. To date, the U.S. National Institutes of Health (NIH) has awarded VistaGen over $8.75 million for development of AV-101. Management anticipates strategically out-licensing AV-101 to a development and marketing partner in 2013.

VistaGen is also developing LiverSafe 3D™, a novel predictive liver toxicity and drug metabolism bioassay system for drug rescue applications. In parallel with drug rescue activities, the Company is funding early-stage nonclinical studies focused on potential cell therapy applications of its Human Clinical Trials in a Test Tube™ platform. 

 
Key Investment Highlights
Proprietary Stem Cell Technology Addressing Heart and Liver Safety Challenges in Drug Development
Drug Rescue Platform Designed to Recapture Prior Pharma R&D Investment in Failed Drug Candidates
Successfully Completed NIH-Funded Phase 1 Program for New Drug Candidate for Neuropathic Pain and Depression
Committed Management, Board and lead investor, Platinum Long Term Growth VII
 


CardioSafe 3D(TM)




 

Stem Cell Technology Advantage: Differentiation



Drug Rescue Model




 
 

Technology: http://www.vistagen.com/technology/default.aspx

Product Line: http://www.vistagen.com/products/Clinical-Trials-in-a-Test-Tube/default.aspx

Business Model: http://www.vistagen.com/business-model/default.aspx

Related Research Videos at Toronto's McEwen Center:

http://www.youtube.com/watch?v=IczZj4Efn54
http://www.vistagen.com/Theme/VistaGen/files/flash/kellerv%20in%20the%20news%20edited.wmv

http://www.vistagen.com/Theme/VistaGen/files/VistaGen_BioWold_v001_y3nela.pdf
 

Management:

Shawn Singh, J.D.
Chief Executive Officer, Director
 
Mr. Singh has over 20 years of experience working with successful public and private biotechnology and pharmaceutical companies, a life sciences venture capital firm, and a profitable contract research and development organization (CRO), serving in numerous senior management roles. Prior to joining us as Chief Executive Officer in August 2009, Mr. Singh served as Managing Principal of Cato BioVentures, the venture capital affiliate of Cato Research, a global, full-service CRO for which he served as Chief Business Officer. Mr. Singh also served as President and Director of Echo Therapeutics (NASDAQ: ECTE), a medical device company developing a non-invasive, wireless, transdermal continuous glucose monitoring (tCGM) system for use in hospital critical care units and for people with diabetes, and as Chief Business Officer of SciClone Pharmaceuticals (NASDAQ: SCLN), a revenue-generating, profitable, specialty pharmaceutical company with a substantial commercial business in China and a product portfolio of therapies for oncology, infectious diseases, and cardiovascular, urological, respiratory, and central nervous system disorders. Mr. Singh began his career as a corporate finance attorney in the Silicon Valley offices of Morrison & Foerster LLP, an international law firm. He is a member of the State Bar of California. 
 
Ralph Snodgrass, Ph.D.
President, Chief Scientific Officer, Director
 
Dr. Snodgrass co-founded VistaGen with Dr. Gordon Keller in 1998 and served as our Chief Executive Officer until August 2009. He has over 18 years of experience in senior biotechnology management, including as Chief Scientific Officer of Progenitor, Inc. He has more than 10 years of research experience as a professor at the Lineberger Comprehensive Cancer Center, University North Carolina Chapel Hill School of Medicine, and as a member of the Institute for Immunology, Basel, Switzerland. Dr. Snodgrass is a past Board Member of the Emerging Company Section of the Biotechnology Industry Organization (BIO), and is a published and recognized pioneering expert in stem cell biology with more than 20 years’ experience in the uses of stem cells as biological tools for drug discovery and development.
 
Jerrold D. Dotson, CPA
Chief Financial Officer, Secretary
 
Mr. Dotson brings a broad base of financial experience to VistaGen, joining as our Chief Financial Officer in September 2011.  Most recently, he served as  Corporate Controller for Discovery Foods.  Mr. Dotson also held various positions in the finance and administration department of Calypte Biomedical Corporation, including his last position as Vice President of Finance and Administration and Corporate Secretary, California & Hawaiian Sugar Company, and The Clorox Company.  He received his B.S. degree (Cum Laude) in accounting  from Abilene Christian College and is a certified public accountant licensed in the State of California. 

Visit VistaGen's website (www.VistaGen.com) for more information on the Management Team, Board of Directors and Scientific Advisory Board Members

 
Transfer Agent:
Holladay Stock Transfer
2939 N. 67th Place
Scottsdale, AZ, 85251
480-481-3940
 
Investor & Media Contact
Shawn K. Singh, JD
Chief Executive Officer
VistaGen Therapeutics, Inc.
T:  650-577-3600      
E: investor.relations@vistagen.com
 
                             VSTA - Daily Candlesticks  
 
                             VSTA - Weekly Candlesticks  


MissionIR is a moderator of this board and has the ability to edit this section as well as remove posts from the board. Please see disclaimer on the MissionIR website: http://disclaimer.missionir.com
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VTGN
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VTGN News: Current Report Filing (8-k) 05:16 PM
VTGN News: Current Report Filing (8-k) 09/22/2016 01:57:53 PM
VTGN News: VistaGen Therapeutics Provides Business Outlook and Sets Corporate Milestones 09/22/2016 08:05:00 AM
VTGN News: Current Report Filing (8-k) 08/17/2016 04:13:04 PM
VTGN News: Quarterly Report (10-q) 08/12/2016 04:09:02 PM
News News Alert: Current Report Filing (8-k) 09/27/2016 05:16:16 PM
PostSubject
#2485   VTGN is now a one trick pony pipeline/company. Seel 09/26/16 07:00:06 PM
#2484   Vistagen Therapeutics May Hold the Key to Treatment nyctraydr 09/08/16 12:23:06 PM
#2483   Thanks much! bigstocksnbonds 09/02/16 12:57:11 PM
#2482   Yes, you can look it up anywhere. dave7933 09/02/16 07:20:15 AM
#2481   VistaGen-- is the correct current symbol VTGN please? Thanks! bigstocksnbonds 09/01/16 10:55:13 PM
#2480   Heard the story today, bought shares. Very impressive dave7933 08/03/16 08:38:25 PM
#2479   REALLY NO BID 06/22/16 10:37:05 PM
#2478   Meet Sean over the weekend. Johnny_C 06/22/16 05:51:06 AM
#2477   VSTA Doses First Patient in Phase IIa Study MissionIR 11/03/15 09:08:17 AM
#2476   $VSTA recent news/filings stocktrademan 06/18/15 02:08:06 PM
#2475   VSTA Aligned with World Health Organization’s Global Call MissionIR 03/30/15 01:28:03 PM
#2474   VSTA Utilizing Stem Cell Technology to Improve Predictability MissionIR 03/20/15 09:18:34 AM
#2473   VSTA's Next-Gen CNS Drug Candidate Poised for Revolutionary Breakthrough MissionIR 03/16/15 05:17:42 PM
#2472   VSTA AV-101 Seen as Safe Ketamine Alternative for MissionIR 03/03/15 09:22:37 AM
#2471   Economic Impacts of Depression Impacts are Staggering – MissionIR 02/27/15 01:55:06 PM
#2470   VSTA Working to Revolutionize Depression Treatment MissionIR 02/24/15 08:20:00 AM
#2469   VSTA Partners with NIH in its Sponsored Phase MissionIR 02/17/15 09:26:52 AM
#2468   VSTA Welcomes Dr. Gerard Sanacora to Clinical and MissionIR 02/05/15 11:13:44 AM
#2467   VSTA – Applying Stem Cell Technology toward Drug MissionIR 01/26/15 03:48:42 PM
#2466   VSTA is Optimistic About Its Depression Medicine MissionIR 01/06/15 01:58:49 PM
#2465   VSTA – Developing Leading-Edge Biotechnology Offerings MissionIR 12/26/14 03:25:48 PM
#2464   VSTA AV-101 Rivals Ketamine and Other Next-Gen Anti-depressants MissionIR 12/16/14 04:48:17 PM
#2463   How is VSTA going to fund the Phase Investman432 12/12/14 04:59:37 PM
#2462   VSTA Embarking on Key Stage 2 Clinical Trial MissionIR 12/12/14 01:31:52 PM
#2461   VSTA's AV-101 Poised to Emerge as a Leading MissionIR 12/11/14 04:58:52 PM
#2460   Withdrawal of Registration Statement on Form S-1 Investman432 12/11/14 01:51:39 PM
#2459   VSTA Authorizes Letter of Intent with NIMH for MissionIR 11/17/14 09:49:56 AM
#2458   VSTA Sees AV-101 as Potential Breakthrough Drug for MissionIR 09/25/14 08:38:41 AM
#2457   Well at least they got someone to do borstalboy 09/25/14 03:52:24 AM
#2456   VSTA is stuck with lead-investor Platinum and, who Investman432 09/24/14 05:55:43 PM
#2455   VSTA Receives Notice of Allowance for Stem Cell Technology MissionIR 08/19/14 09:56:29 AM
#2454   VSTA Provides Reverse Stock Split FAQs MissionIR 08/18/14 06:15:41 PM
#2452   http://otcbb.com/asp/dailylist_detail.asp?d=08/13/2014&mkt_ctg=ALL EmptyBones 08/13/14 04:57:48 PM
#2451   VSTA one for 20 reverse split: Renee 08/13/14 04:51:43 PM
#2450   where di you get this EARL69 08/13/14 04:38:15 PM
#2449   12:52 8/14/2014 VSTA VistaGen Therapeutics, Inc. Common Stock EmptyBones 08/13/14 01:43:58 PM
#2448   VSTA shareholders have little to celebrate, as management Investman432 07/31/14 07:42:13 AM
#2447   Bid / Ask spread is gaping. Lucky Investman432 07/25/14 04:11:12 PM
#2446   INTERESTING BGMO 36 MILLION !! I WONDER EARL69 07/23/14 11:55:55 AM
#2445   What can a shareholder infer from this agreement Investman432 07/22/14 01:51:55 PM
#2444   VSTA Announces New Agreement with Largest Shareholder MissionIR 07/22/14 11:28:17 AM
#2443   Did Shawn give up? No Investman432 07/21/14 12:17:43 PM
#2442   Millions in Grant Funding Provide Foundation of Opportunity MissionIR 07/15/14 02:49:42 PM
#2441   VSTA at Forefront of Stem Cell Technology for MissionIR 07/08/14 05:37:41 PM
#2440   That BGMO is making a great investment??? RealWorld1 07/02/14 03:43:38 PM
#2439   Amazing, U.S. pharmaceutical industry pumped more than $51 Investman432 07/02/14 01:09:00 PM
#2438   VSTA Drug Rescue Model Resuscitates Failed Drug Candidates MissionIR 07/01/14 11:22:36 AM
#2437   Yes, but there is an obligation to provide borstalboy 06/28/14 04:21:05 AM
#2436   Salim Chamdia blows up another company and burns KGB008 06/28/14 03:18:51 AM
#2435   Salim Chamdia the low life scum bag is KGB008 06/28/14 03:14:56 AM
PostSubject