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VistaGen Therapeutics, Inc. (VTGN)

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Last Post: 3/29/2017 9:09:23 AM - Followers: 51 - Board type: Free - Posts Today: 0

VistaGen Therapeutics, Inc. (VSTA)

VistaGen Investor Summary:

VistaGen Interview with MissionIR:

VistaGen 2014 10-K

Company Profile

VistaGen Therapeutics, Inc. is a biotechnology company applying stem cell technology for drug rescue and cell therapy. Drug rescue combines human stem cell technology with modern medicinal chemistry to generate new chemical variants ("drug rescue variants") of once-promising drug candidates that have been discontinued during late-stage preclinical development due to heart or liver safety concerns. VistaGen also focuses on cell therapy, or regenerative medicine, which includes repairing, replacing or restoring damaged tissues or organs.

VistaGen's versatile stem cell technology platform, Human Clinical Trials in a Test Tube™, has been developed to provide clinically relevant predictions of potential heart and liver toxicity of promising new drug candidates long before they are ever tested on humans.

By more closely approximating human biology than conventional animal studies and other nonclinical techniques and technologies currently used in drug development, VistaGen's human stem cell-based bioassay systems can improve the predictability of the drug development cycle and lower the cost of new drug research and development by identifying product failures earlier in the cost curve. According to the Food and Drug Administration even only a ten percent improvement in predicting failure before clinical trials could save $100 million in development costs, which savings ultimately could be passed on to patients.

Using mature human heart cells produced from stem cells, VistaGen has developed and internally validated CardioSafe 3D™, a novel three-dimensional (3D) bioassay system for predicting the in vivo cardiac effects of new drug candidates before they are tested in humans. VistaGen is now focused on using CardioSafe 3D™ to generate up to two new, safer small molecule drug rescue variants every twelve to eighteen months. VistaGen anticipates that these drug rescue variants will be modified versions of once-promising new drug candidates that have been discontinued by pharmaceutical companies and academic research institutions because of heart toxicity concerns, despite substantial prior investment and positive efficacy data demonstrating their potential therapeutic and commercial benefits. In most cases, VistaGen plans to license or sell its new, safer drug rescue variants in strategic partnering arrangements with global pharmaceutical companies, arrangements providing VistaGen with both near term and downstream milestone payments and economic participation rights but without future development cost obligations.

AV-101, VistaGen's lead small molecule prodrug candidate, has successfully completed Phase I clinical development in the U.S. for treatment of neuropathic pain, a serious and chronic condition affecting millions of people worldwide, depression, and other neurological diseases and conditions. To date, the U.S. National Institutes of Health (NIH) has awarded VistaGen over $8.75 million for development of AV-101. Management anticipates strategically out-licensing AV-101 to a development and marketing partner in 2013.

VistaGen is also developing LiverSafe 3D™, a novel predictive liver toxicity and drug metabolism bioassay system for drug rescue applications. In parallel with drug rescue activities, the Company is funding early-stage nonclinical studies focused on potential cell therapy applications of its Human Clinical Trials in a Test Tube™ platform. 

Key Investment Highlights
Proprietary Stem Cell Technology Addressing Heart and Liver Safety Challenges in Drug Development
Drug Rescue Platform Designed to Recapture Prior Pharma R&D Investment in Failed Drug Candidates
Successfully Completed NIH-Funded Phase 1 Program for New Drug Candidate for Neuropathic Pain and Depression
Committed Management, Board and lead investor, Platinum Long Term Growth VII

CardioSafe 3D(TM)


Stem Cell Technology Advantage: Differentiation

Drug Rescue Model



Product Line:

Business Model:

Related Research Videos at Toronto's McEwen Center:


Shawn Singh, J.D.
Chief Executive Officer, Director
Mr. Singh has over 20 years of experience working with successful public and private biotechnology and pharmaceutical companies, a life sciences venture capital firm, and a profitable contract research and development organization (CRO), serving in numerous senior management roles. Prior to joining us as Chief Executive Officer in August 2009, Mr. Singh served as Managing Principal of Cato BioVentures, the venture capital affiliate of Cato Research, a global, full-service CRO for which he served as Chief Business Officer. Mr. Singh also served as President and Director of Echo Therapeutics (NASDAQ: ECTE), a medical device company developing a non-invasive, wireless, transdermal continuous glucose monitoring (tCGM) system for use in hospital critical care units and for people with diabetes, and as Chief Business Officer of SciClone Pharmaceuticals (NASDAQ: SCLN), a revenue-generating, profitable, specialty pharmaceutical company with a substantial commercial business in China and a product portfolio of therapies for oncology, infectious diseases, and cardiovascular, urological, respiratory, and central nervous system disorders. Mr. Singh began his career as a corporate finance attorney in the Silicon Valley offices of Morrison & Foerster LLP, an international law firm. He is a member of the State Bar of California. 
Ralph Snodgrass, Ph.D.
President, Chief Scientific Officer, Director
Dr. Snodgrass co-founded VistaGen with Dr. Gordon Keller in 1998 and served as our Chief Executive Officer until August 2009. He has over 18 years of experience in senior biotechnology management, including as Chief Scientific Officer of Progenitor, Inc. He has more than 10 years of research experience as a professor at the Lineberger Comprehensive Cancer Center, University North Carolina Chapel Hill School of Medicine, and as a member of the Institute for Immunology, Basel, Switzerland. Dr. Snodgrass is a past Board Member of the Emerging Company Section of the Biotechnology Industry Organization (BIO), and is a published and recognized pioneering expert in stem cell biology with more than 20 years’ experience in the uses of stem cells as biological tools for drug discovery and development.
Jerrold D. Dotson, CPA
Chief Financial Officer, Secretary
Mr. Dotson brings a broad base of financial experience to VistaGen, joining as our Chief Financial Officer in September 2011.  Most recently, he served as  Corporate Controller for Discovery Foods.  Mr. Dotson also held various positions in the finance and administration department of Calypte Biomedical Corporation, including his last position as Vice President of Finance and Administration and Corporate Secretary, California & Hawaiian Sugar Company, and The Clorox Company.  He received his B.S. degree (Cum Laude) in accounting  from Abilene Christian College and is a certified public accountant licensed in the State of California. 

Visit VistaGen's website ( for more information on the Management Team, Board of Directors and Scientific Advisory Board Members

Transfer Agent:
Holladay Stock Transfer
2939 N. 67th Place
Scottsdale, AZ, 85251
Investor & Media Contact
Shawn K. Singh, JD
Chief Executive Officer
VistaGen Therapeutics, Inc.
T:  650-577-3600      
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Current Price
Bid Ask Day's Range
VTGN News: Securities Registration Statement (simplified Form) (s-3/a) 04/04/2017 04:56:25 PM
VTGN News: Current Report Filing (8-k) 03/29/2017 04:18:46 PM
VTGN News: VistaGen Therapeutics Inc. (Nasdaq: VTGN) to Ring The Nasdaq Stock Market Closing Bell 03/10/2017 03:17:22 PM
VTGN News: Quarterly Report (10-q) 02/13/2017 04:31:39 PM
VTGN News: Amended Statement of Ownership (sc 13g/a) 01/27/2017 12:19:00 PM
#2508 Moto260 03/29/17 09:09:23 AM
#2507   Does anyone know about when the next results valeriana 03/08/17 07:40:21 PM
#2506   Googled Hillard and came across this post. Humantruth 02/16/17 05:35:02 PM
#2505   I think just the opposite. I usually don't Johnny_C 02/01/17 07:54:53 PM
#2504   Hey Zal, this one could be a grand Johnny_C 02/01/17 07:09:34 PM
#2503   Hey Zal, this one could be a grand Johnny_C 02/01/17 07:09:33 PM
#2502   I don't see message board posters pumping this. Johnny_C 02/01/17 07:07:06 PM
#2501   Keeps going down on higher volume. Not a kwazeetech1 01/31/17 04:34:37 PM
#2500   That certainly could be a reason....but I think otherwise! zalicuslicious 01/30/17 02:44:03 PM
#2499   Looking at the large and quick drop in kwazeetech1 01/30/17 01:47:41 PM
#2498   They should have phase 2b results out in/around zalicuslicious 01/29/17 12:33:23 PM
#2497   What happens in 3 months? kwazeetech1 01/29/17 12:26:30 PM
#2496   Please let me know if this is a zalicuslicious 01/24/17 10:49:13 AM
#2495   What the MMs are doing is selling...message board kwazeetech1 01/24/17 10:46:58 AM
#2494   Volume alert. Over daily average in 1st murocman 01/13/17 10:18:51 AM
#2493   I'm buying now before anybody discovers this gem.....why zalicuslicious 01/12/17 03:29:28 PM
#2492   Is this another Seth Shaw pumpNdump? diannedawn 01/12/17 10:15:13 AM
#2491   Simple answers, more sellers than buyers. Hedge fund Johnny_C 12/19/16 09:46:41 AM
#2490   Why did the stock just drop below the kwazeetech1 12/17/16 04:31:05 PM
#2489   Nice news on VTGN today. Pretty cool Johnny_C 12/14/16 01:53:53 PM
#2487   You bet...tell us again what Seth Shaw's connection diannedawn 10/25/16 11:32:08 AM
#2486   It looks like a very good play. Not Johnny_C 10/04/16 05:50:22 PM
#2485   VTGN is now a one trick pony pipeline/company. Seel 09/26/16 07:00:06 PM
#2484   Vistagen Therapeutics May Hold the Key to Treatment nyctraydr 09/08/16 12:23:06 PM
#2483   Thanks much! bigstocksnbonds 09/02/16 12:57:11 PM
#2482   Yes, you can look it up anywhere. dave7933 09/02/16 07:20:15 AM
#2481   VistaGen-- is the correct current symbol VTGN please? Thanks! bigstocksnbonds 09/01/16 10:55:13 PM
#2480   Heard the story today, bought shares. Very impressive dave7933 08/03/16 08:38:25 PM
#2479   REALLY $$CHIHUAHUA$$ 06/22/16 10:37:05 PM
#2478   Meet Sean over the weekend. Johnny_C 06/22/16 05:51:06 AM
#2477   VSTA Doses First Patient in Phase IIa Study MissionIR 11/03/15 09:08:17 AM
#2476   $VSTA recent news/filings stocktrademan 06/18/15 02:08:06 PM
#2475   VSTA Aligned with World Health Organization’s Global Call MissionIR 03/30/15 01:28:03 PM
#2474   VSTA Utilizing Stem Cell Technology to Improve Predictability MissionIR 03/20/15 09:18:34 AM
#2473   VSTA's Next-Gen CNS Drug Candidate Poised for Revolutionary Breakthrough MissionIR 03/16/15 05:17:42 PM
#2472   VSTA AV-101 Seen as Safe Ketamine Alternative for MissionIR 03/03/15 09:22:37 AM
#2471   Economic Impacts of Depression Impacts are Staggering – MissionIR 02/27/15 01:55:06 PM
#2470   VSTA Working to Revolutionize Depression Treatment MissionIR 02/24/15 08:20:00 AM
#2469   VSTA Partners with NIH in its Sponsored Phase MissionIR 02/17/15 09:26:52 AM
#2468   VSTA Welcomes Dr. Gerard Sanacora to Clinical and MissionIR 02/05/15 11:13:44 AM
#2467   VSTA – Applying Stem Cell Technology toward Drug MissionIR 01/26/15 03:48:42 PM
#2466   VSTA is Optimistic About Its Depression Medicine MissionIR 01/06/15 01:58:49 PM
#2465   VSTA – Developing Leading-Edge Biotechnology Offerings MissionIR 12/26/14 03:25:48 PM
#2464   VSTA AV-101 Rivals Ketamine and Other Next-Gen Anti-depressants MissionIR 12/16/14 04:48:17 PM
#2463   How is VSTA going to fund the Phase Investman432 12/12/14 04:59:37 PM
#2462   VSTA Embarking on Key Stage 2 Clinical Trial MissionIR 12/12/14 01:31:52 PM
#2461   VSTA's AV-101 Poised to Emerge as a Leading MissionIR 12/11/14 04:58:52 PM
#2460   Withdrawal of Registration Statement on Form S-1 Investman432 12/11/14 01:51:39 PM
#2459   VSTA Authorizes Letter of Intent with NIMH for MissionIR 11/17/14 09:49:56 AM
#2458   VSTA Sees AV-101 as Potential Breakthrough Drug for MissionIR 09/25/14 08:38:41 AM