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RXI Pharmaceuticals Corp (RXII)

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Moderator: No Moderator ash111, the submariner, Inoviorulez, pistol1p
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Last Post: 8/28/2015 2:46:50 PM - Followers: 126 - Board type: Free - Posts Today: 6

About RXi Pharmaceuticals

RXi Pharmaceuticals Corporation (OTC: RXII) is a biotechnology company focused on discovering, developing and commercializing innovative therapies based on its proprietary, next-generation RNAi platform.  Therapeutics that use RNA interference, or "RNAi," have great promise because of their ability to "silence," or down-regulate, the expression of a specific gene that may be overexpressed in a disease condition.  Building on the pioneering work of scientific founder and Nobel Laureate Dr. Craig Mello, RXi's first RNAi product candidate, RXI-109, entered into RXi's first human clinical trial in 2012.  RXI-109 targets connective tissue growth factor (CTGF), a key regulatory of fibrosis and scar formation, and is initially being developed to reduce or inhibit scar formation in the skin following surgery.


RXi Pharmaceuticals Corp., has received patent approval for their new experimental breast cancer vaccine which became part of the company's arsenal after acquiring Apthera Inc. in April of this year.
The specific patents in question regard using the vaccine NeuVax with the drug Herceptin which is used in women to slow the production of the HER2 protein in tumors, while NeuVax attempts to make the body's immune system fight off cancerous cells.
According to The Telegram:
"The patents also cover using NeuVax in patients not eligible for Herceptin treatment."
With their patent in place the company plans to begin human tests in early 2012.
According to RXi the patents were developed by Dr. George E. Peoples, director of the Cancer Vaccine Development Program for the U.S. Military Cancer Institute and RXi is leasing the patents for their own work.


This May, RXi Pharmaceuticals Corp. observed two momentous events: The biotechnology company completed its spinoff from Galena Biopharma Inc., and Dr. Geert Cauwenbergh took the helm as president and chief executive officer. The small company's first product, an anti-scarring medication called RXI-109, entered clinical trials this year, and is based on the pioneering work in RNA interference of RXi scientific founder and Nobel Laureate Dr. Craig C. Mello. Dr. Cauwenbergh came to RXi after a long career in pharmaceuticals, most recently as president and chief executive officer of a company he founded, Barrier Therapeutics. What attracted you to come to Worcester? "It was the technology, well, the technology and the chemistry with these people. They're very bright." As a publicly traded company, how do you reconcile the needs of the investors, which are sometimes a short-term desire for profits, with the needs of medical research, which sometimes takes years? "Through business development. Basically what you do as a small biotech is you try to create a big network with people who have interest in various stages of development. ... In two or three years they get antsy and they want to cash in, but at that point in time there will be and there is already a network of business development contacts in place where you can for instance get nondiluted money without having to raise money and go back to the stock market and shareholders by making regional deals or geographic deals ...


June 9, 2015 RXi Pharmaceuticals Strengthens Intellectual Property Portfolio for Novel RNAi Platform

Dec 17, 2014 RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301

Press Releases
RXi Pharmaceuticals to Present at Biotech Showcase™ 2013 - December 19, 2012
RXi Pharmaceuticals Announces Initiation of Second Double-Blind Vehicle Controlled Phase 1 Study With Its Anti-Scarring Compound, RXI-109 - December 5, 2012
RXi Pharmaceuticals Announces Pharmacokinetic Results of its Single Dose Phase 1 Study with RXI-109 in Healthy Volunteers - November 15, 2012
RXi Pharmaceuticals Reports Financial Results for the Third Quarter of 2012 - November 14, 2012
RXi Pharmaceuticals to Present at 12th Annual Biotech Symposium - October 16, 2012
RXi Pharmaceuticals Awarded NCI SBIR Funding to Advance Self-Delivering RNAi Technology - October 4, 2012
RXi Pharmaceuticals to Present at 11th Annual BIO Investor Forum - October 2, 2012
RXi Pharmaceuticals Announces Completion of Dosing in Phase 1 Trial for RXI-109 Program - September 24, 2012
RXi Pharmaceuticals Reports Financial Results for the Second Quarter of 2012 - August 15, 2012
RXi Pharmaceuticals Appoints Jeannette Graf MD and Leroy Young MD to its Scientific Advisory Board - July 13, 2012
Share Statistics
Avg Vol (3 month)3: 215,443
Avg Vol (10 day)3: 145,371
Shares Outstanding5: 338m
Float: 53.34M
% Held by Insiders1: 9.01%
% Held by Institutions1: 0.50%

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Current Price
Bid Ask Day's Range
#2282  Sticky Note RXII, DD: a solid NASDAQ stock,low market cap ash111 06/25/15 04:36:07 PM
#1762  Sticky Note FBR Capital rates RXII a "Hold" rating with Inoviorulez 04/09/15 01:56:19 PM
#2525   News coming. zoriden 08/28/15 02:46:50 PM
#2524   I hope so or even higher then that. dave86 08/28/15 02:37:28 PM
#2523   Good move dude we could see .58s $RXII TechnoAnalyst 08/28/15 01:14:35 PM
#2522   Grabbed 14740 shares so far this morning. I'm In! dave86 08/28/15 11:39:55 AM
#2521   What is that means? You mean when to wildbullus 08/28/15 10:47:16 AM
#2520   In the Q&A section Geert gave a big The Other Guy 08/28/15 10:12:46 AM
#2519   The 30 day wait period is over coinguy 08/27/15 10:36:30 AM
#2518   Rxi submitted IND for RXI-109 ash111 08/26/15 08:01:08 AM
#2517   This could be trading way over $1 on ash111 08/26/15 01:11:01 AM
#2516   Me neither, I posted that incase there some craig76 08/26/15 12:45:37 AM
#2515   I don't expect them to need the extension. The Other Guy 08/25/15 11:42:29 PM
#2514   I almost certain they would get another 180 craig76 08/25/15 10:37:16 PM
#2513   Oh man, brain freeze......yeah.....thanks for the information. Citrati 08/25/15 10:01:56 PM
#2512   Trying to get up to date with TPIV. The Other Guy 08/25/15 09:36:12 PM
#2511   Short interest down about 400k: The Other Guy 08/25/15 09:33:54 PM
#2510   Trying to get up to date with TPIV. Citrati 08/25/15 09:21:07 PM
#2509   You are right.deleted. ash111 08/25/15 06:14:38 PM
#2508   That IIS holdings is wrong on their website. InternetForumUser 08/25/15 05:41:19 PM
#2507;_ylt=ApPa14fTcwwosWUm6ND8yz_eAohG;_y ash111 08/25/15 05:25:59 PM
#2505   Looking good RXII link back to DD +UPDATES:(relating ash111 08/25/15 02:50:39 PM
#2504   Here's the post by $heff from his biotech value1008 08/25/15 02:38:38 PM
#2503   Great to hear! More confidence in the The Other Guy 08/25/15 02:25:33 PM
#2502   Jumping in, looks interesting. Jongkey 08/25/15 02:24:03 PM
#2501   Much of Volume spike is $Sheff and company Citrati 08/25/15 02:22:19 PM
#2500   What news? We have a volume spike. The Other Guy 08/25/15 02:20:27 PM
#2499   You are basically saying the market cap for The Other Guy 08/25/15 02:17:04 PM
#2498   Nice news 10 min ago! harmsen 08/25/15 02:15:03 PM
#2497   No news or bad news will tank to Kev_Sh 08/25/15 11:25:57 AM
#2496   So IND filed and approved or good results million_dollar_mafia 08/24/15 11:39:57 PM
#2495   I think the price will tank to the Kev_Sh 08/24/15 04:16:06 PM
#2494   Bids been creeping up all day..and a lot the submariner 08/24/15 02:13:37 PM
#2493   Market sucks. Needs ridiculous good news for anything million_dollar_mafia 08/24/15 01:49:13 PM
#2492   Got some strong bid support today. the submariner 08/24/15 10:34:24 AM
#2491 brancoo0 08/21/15 08:53:42 AM
#2490   Is something happening? Volume is up. The Other Guy 08/20/15 09:42:34 AM
#2489   Couldn't resist bought a good amount more today.Very zoriden 08/20/15 01:51:00 AM
#2488   That they did, but that is the past. Inoviorulez 08/19/15 05:25:26 PM
#2487   Agreed. They made their money in the dividends. The Other Guy 08/18/15 07:49:30 PM
#2486   Good riddance on Tang! value1008 08/18/15 03:05:01 PM
#2485   Don't look at that info use the Nasdaq Inoviorulez 08/17/15 08:00:23 PM
#2484   Tang is gone, he even sold out all Inoviorulez 08/17/15 07:59:52 PM
#2483   A good thread well worth reading. Titan V 08/17/15 11:51:23 AM
#2482   Correct. Seems incredibly low. The markets for RNAi The Other Guy 08/15/15 01:00:50 PM
#2481   This stock has a 25 million MC. Seems pennyplayer777 08/15/15 12:10:32 PM
#2480   Thanks. If there is one negative I have The Other Guy 08/15/15 11:58:58 AM
#2479   That's the info scottrade has on there site. pennyplayer777 08/15/15 11:30:13 AM
#2478   Where? The Other Guy 08/15/15 11:28:23 AM
#2477   I'm showing SO at 65 mil. and pennyplayer777 08/15/15 10:55:11 AM
#2476   IFU, adding to our conversation yesterday, I ask The Other Guy 08/15/15 10:33:53 AM
#2475   The RXI website has 21,132,021 shares outstanding. The Other Guy 08/15/15 10:26:13 AM