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RXI Pharmaceuticals Corp (RXII)

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Last Post: 4/18/2014 8:44:20 AM - Followers: 67 - Board type: Free - Posts Today: 0

About RXi Pharmaceuticals

RXi Pharmaceuticals Corporation (OTC: RXII) is a biotechnology company focused on discovering, developing and commercializing innovative therapies based on its proprietary, next-generation RNAi platform.  Therapeutics that use RNA interference, or "RNAi," have great promise because of their ability to "silence," or down-regulate, the expression of a specific gene that may be overexpressed in a disease condition.  Building on the pioneering work of scientific founder and Nobel Laureate Dr. Craig Mello, RXi's first RNAi product candidate, RXI-109, entered into RXi's first human clinical trial in 2012.  RXI-109 targets connective tissue growth factor (CTGF), a key regulatory of fibrosis and scar formation, and is initially being developed to reduce or inhibit scar formation in the skin following surgery.

RXi Pharmaceuticals Corp., has received patent approval for their new experimental breast cancer vaccine which became part of the company's arsenal after acquiring Apthera Inc. in April of this year.
The specific patents in question regard using the vaccine NeuVax with the drug Herceptin which is used in women to slow the production of the HER2 protein in tumors, while NeuVax attempts to make the body's immune system fight off cancerous cells.
According to The Telegram:
"The patents also cover using NeuVax in patients not eligible for Herceptin treatment."
With their patent in place the company plans to begin human tests in early 2012.
According to RXi the patents were developed by Dr. George E. Peoples, director of the Cancer Vaccine Development Program for the U.S. Military Cancer Institute and RXi is leasing the patents for their own work.

This May, RXi Pharmaceuticals Corp. observed two momentous events: The biotechnology company completed its spinoff from Galena Biopharma Inc., and Dr. Geert Cauwenbergh took the helm as president and chief executive officer. The small company's first product, an anti-scarring medication called RXI-109, entered clinical trials this year, and is based on the pioneering work in RNA interference of RXi scientific founder and Nobel Laureate Dr. Craig C. Mello. Dr. Cauwenbergh came to RXi after a long career in pharmaceuticals, most recently as president and chief executive officer of a company he founded, Barrier Therapeutics. What attracted you to come to Worcester? "It was the technology, well, the technology and the chemistry with these people. They're very bright." As a publicly traded company, how do you reconcile the needs of the investors, which are sometimes a short-term desire for profits, with the needs of medical research, which sometimes takes years? "Through business development. Basically what you do as a small biotech is you try to create a big network with people who have interest in various stages of development. ... In two or three years they get antsy and they want to cash in, but at that point in time there will be and there is already a network of business development contacts in place where you can for instance get nondiluted money without having to raise money and go back to the stock market and shareholders by making regional deals or geographic deals ...

Press Releases
RXi Pharmaceuticals to Present at Biotech Showcase™ 2013 - December 19, 2012
RXi Pharmaceuticals Announces Initiation of Second Double-Blind Vehicle Controlled Phase 1 Study With Its Anti-Scarring Compound, RXI-109 - December 5, 2012
RXi Pharmaceuticals Announces Pharmacokinetic Results of its Single Dose Phase 1 Study with RXI-109 in Healthy Volunteers - November 15, 2012
RXi Pharmaceuticals Reports Financial Results for the Third Quarter of 2012 - November 14, 2012
RXi Pharmaceuticals to Present at 12th Annual Biotech Symposium - October 16, 2012
RXi Pharmaceuticals Awarded NCI SBIR Funding to Advance Self-Delivering RNAi Technology - October 4, 2012
RXi Pharmaceuticals to Present at 11th Annual BIO Investor Forum - October 2, 2012
RXi Pharmaceuticals Announces Completion of Dosing in Phase 1 Trial for RXI-109 Program - September 24, 2012
RXi Pharmaceuticals Reports Financial Results for the Second Quarter of 2012 - August 15, 2012
RXi Pharmaceuticals Appoints Jeannette Graf MD and Leroy Young MD to its Scientific Advisory Board - July 13, 2012

Share Statistics
Avg Vol (3 month)3: 215,443
Avg Vol (10 day)3: 145,371
Shares Outstanding5: 338m
Float: 53.34M
% Held by Insiders1: 9.01%
% Held by Institutions1: 0.50%


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RXII News: RXi Pharmaceuticals Granted Key Patent Related to Self-Delivering Technology for the Treatment of Fibrotic Disorders 03/05/2014 07:02:00 AM
RXII News: RXi Pharmaceuticals to Present at the 24th Annual Wall Street Analyst Forum 02/24/2014 07:02:00 AM
RXII News: OTC Markets Group Congratulates RXI Pharmaceuticals on NASDAQ Listing 02/11/2014 10:00:00 AM
RXII News: RXi Pharmaceuticals Announces Listing on NASDAQ Capital Market 02/11/2014 07:02:00 AM
RXII News: RXi Pharmaceuticals to Present at the 16th Annual BIO CEO & Investor Conference 02/03/2014 07:02:00 AM
#1291   so what of it?? 1 million 04/18/14 08:44:20 AM
#1290   Today April 17th from FLYONTHEWALL news " Inoviorulez 04/17/14 07:17:47 PM
#1289   For those of you who may be curious Titan V 04/17/14 02:19:22 PM
#1288   Yea,tick tock tick tock the magical clock..... 1 million 04/16/14 09:09:12 PM
#1287   I'm excited to know what this is for. Titan V 04/16/14 04:30:04 PM
#1286   Another CTO (Confidential Treatment Order) was just filed! Inoviorulez 04/16/14 02:09:24 PM
#1285   okay,that seems hopeful... 1 million 04/07/14 10:08:21 AM
#1284   Between the results of the trial do out the submariner 04/07/14 08:33:05 AM
#1283   The only thing going on is the price dropping!!!! 1 million 04/07/14 08:29:24 AM
#1282   Starting to look interesting around here. the submariner 04/07/14 08:19:25 AM
#1281   Any one got a input w/ Friday the 1 million 04/06/14 02:05:45 PM
#1279   Hey thanks for your response/input,but still a scray 1 million 04/01/14 07:27:26 AM
#1278   Because biotech has been selling off the last Inoviorulez 03/31/14 06:18:54 PM
#1277   ANYONE HERE AS TO WHY WERE GETTING BURIED 1 million 03/31/14 05:42:18 PM
#1276   Maybe around May or June 2013. 30:1 louieblouie 03/31/14 12:11:05 AM
#1275   Gonia,Ik it was spun off from cytr years the submariner 03/30/14 07:44:39 AM
#1274   RXII - can someone tell me when was gonia 03/29/14 10:28:33 PM
#1273   I think it's more of a sectorwide reaction Titan V 03/27/14 01:21:27 PM
#1272   So why are we getting crushed? mr10001 03/27/14 11:58:42 AM
#1271   Great article, thanks for sharing! I've owned RXII Titan V 03/18/14 10:27:04 AM
#1270   Good SA article on Three RNAi companies check Inoviorulez 03/18/14 10:13:58 AM
#1269   Rxi will be presenting at 3 presentations coming Inoviorulez 03/15/14 10:37:59 AM
#1268   RXII announces 3 presentations in March! Titan V 03/14/14 09:28:36 AM
#1267   RXi Could Sign the Next Deal wildbullus 03/13/14 07:52:48 PM
#1266   Someone on YMB compared RXII to ICPT with Titan V 03/13/14 10:33:17 AM
#1265   I could not tune in, thank you for Titan V 03/11/14 09:22:52 PM
#1264   Key Notes from ROTH presentation new info! Inoviorulez 03/11/14 08:15:54 PM
#1263   Wow, great news to start the weekend! Next Titan V 03/07/14 07:49:30 PM
#1262   Someone mentioned this to me so it seems Inoviorulez 03/07/14 07:46:29 PM
#1261   Nice article, thanks for sharing. Nice after hours Titan V 03/05/14 08:32:58 PM
#1260   Also a nice article talking about Rxi Pharmaceutical's Inoviorulez 03/05/14 03:48:02 PM
#1259   Fantastic! Thanks for posting. Titan V 03/05/14 10:34:52 AM
#1258   Yep another good step for RXII key patent Inoviorulez 03/05/14 08:59:22 AM
#1257   Key patent granted relaed to rx-sdRNAi,,,,,,,,,,,,,, WESTBOROUGH, Mass., March lucky9 03/05/14 07:26:08 AM
#1256   Rxi Pharmaceuticals to Present at the 26th Annual Inoviorulez 03/04/14 08:15:49 AM
#1255   Any news that will push us into the Titan V 03/02/14 06:50:10 PM
#1254   $RXII We will hear from RXi that application wildbullus 03/02/14 04:28:42 PM
#1253   Love RXII..Good results good safety. zoriden 03/02/14 10:04:19 AM
#1252   yes everytime RXII presents at a presentation they Inoviorulez 03/01/14 10:59:44 PM
#1251   Someone on YMB wrote that RXII sent him Titan V 03/01/14 02:21:31 PM
#1250   Yep Monday is the Wall sTreet analyst forum Inoviorulez 02/27/14 04:12:07 PM
#1249   Things are looking very good before the WSA Titan V 02/27/14 11:55:48 AM
#1248   Looking good for today we seemed to consolidate Inoviorulez 02/25/14 09:24:23 PM
#1247   the submariner nimbustux 02/25/14 09:38:11 AM
#1246   Come a long way from the cytr days..lets roll. the submariner 02/25/14 07:16:21 AM
#1245   Indeed! I've been invested in RXII from the Titan V 02/24/14 07:25:45 PM
#1244   Holding 1.200.000 shares before reverse split. GR11 02/24/14 04:06:41 PM
#1243   Will we close above $6? We shall find Titan V 02/24/14 02:58:07 PM
#1242   An update before this meeting would be fantastic. Titan V 02/24/14 09:17:29 AM
#1241   "RXi Pharmaceuticals to Present at the 24th Annual Inoviorulez 02/24/14 07:39:22 AM