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RXI Pharmaceuticals Corp (RXII)

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Last Post: 6/27/2016 6:41:13 PM - Followers: 137 - Board type: Free - Posts Today: 0

About RXi Pharmaceuticals

RXi Pharmaceuticals Corporation (OTC: RXII) is a biotechnology company focused on discovering, developing and commercializing innovative therapies based on its proprietary, next-generation RNAi platform.  Therapeutics that use RNA interference, or "RNAi," have great promise because of their ability to "silence," or down-regulate, the expression of a specific gene that may be overexpressed in a disease condition.  Building on the pioneering work of scientific founder and Nobel Laureate Dr. Craig Mello, RXi's first RNAi product candidate, RXI-109, entered into RXi's first human clinical trial in 2012.  RXI-109 targets connective tissue growth factor (CTGF), a key regulatory of fibrosis and scar formation, and is initially being developed to reduce or inhibit scar formation in the skin following surgery.


RXi Pharmaceuticals Corp., has received patent approval for their new experimental breast cancer vaccine which became part of the company's arsenal after acquiring Apthera Inc. in April of this year.
The specific patents in question regard using the vaccine NeuVax with the drug Herceptin which is used in women to slow the production of the HER2 protein in tumors, while NeuVax attempts to make the body's immune system fight off cancerous cells.
According to The Telegram:
"The patents also cover using NeuVax in patients not eligible for Herceptin treatment."
With their patent in place the company plans to begin human tests in early 2012.
According to RXi the patents were developed by Dr. George E. Peoples, director of the Cancer Vaccine Development Program for the U.S. Military Cancer Institute and RXi is leasing the patents for their own work.


This May, RXi Pharmaceuticals Corp. observed two momentous events: The biotechnology company completed its spinoff from Galena Biopharma Inc., and Dr. Geert Cauwenbergh took the helm as president and chief executive officer. The small company's first product, an anti-scarring medication called RXI-109, entered clinical trials this year, and is based on the pioneering work in RNA interference of RXi scientific founder and Nobel Laureate Dr. Craig C. Mello. Dr. Cauwenbergh came to RXi after a long career in pharmaceuticals, most recently as president and chief executive officer of a company he founded, Barrier Therapeutics. What attracted you to come to Worcester? "It was the technology, well, the technology and the chemistry with these people. They're very bright." As a publicly traded company, how do you reconcile the needs of the investors, which are sometimes a short-term desire for profits, with the needs of medical research, which sometimes takes years? "Through business development. Basically what you do as a small biotech is you try to create a big network with people who have interest in various stages of development. ... In two or three years they get antsy and they want to cash in, but at that point in time there will be and there is already a network of business development contacts in place where you can for instance get nondiluted money without having to raise money and go back to the stock market and shareholders by making regional deals or geographic deals ...


June 9, 2015 RXi Pharmaceuticals Strengthens Intellectual Property Portfolio for Novel RNAi Platform

Dec 17, 2014 RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301

Press Releases
RXi Pharmaceuticals to Present at Biotech Showcase™ 2013 - December 19, 2012
RXi Pharmaceuticals Announces Initiation of Second Double-Blind Vehicle Controlled Phase 1 Study With Its Anti-Scarring Compound, RXI-109 - December 5, 2012
RXi Pharmaceuticals Announces Pharmacokinetic Results of its Single Dose Phase 1 Study with RXI-109 in Healthy Volunteers - November 15, 2012
RXi Pharmaceuticals Reports Financial Results for the Third Quarter of 2012 - November 14, 2012
RXi Pharmaceuticals to Present at 12th Annual Biotech Symposium - October 16, 2012
RXi Pharmaceuticals Awarded NCI SBIR Funding to Advance Self-Delivering RNAi Technology - October 4, 2012
RXi Pharmaceuticals to Present at 11th Annual BIO Investor Forum - October 2, 2012
RXi Pharmaceuticals Announces Completion of Dosing in Phase 1 Trial for RXI-109 Program - September 24, 2012
RXi Pharmaceuticals Reports Financial Results for the Second Quarter of 2012 - August 15, 2012
RXi Pharmaceuticals Appoints Jeannette Graf MD and Leroy Young MD to its Scientific Advisory Board - July 13, 2012
Share Statistics
Avg Vol (3 month)3: 215,443
Avg Vol (10 day)3: 145,371
Shares Outstanding5: 338m
Float: 53.34M
% Held by Insiders1: 9.01%
% Held by Institutions1: 0.50%

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Current Price
Bid Ask Day's Range
#3640  Sticky Note Rxi Pharmaceuticals (RXII) Research Report 2016 Inoviorulez 06/19/16 09:15:20 AM
#3704   First down day in 5 trading days. Let's The Other Guy 06/27/16 06:41:13 PM
#3703   Very few companies have less than 2% short The Other Guy 06/26/16 08:40:25 AM
#3702   yah 2% is not a lot of short Inoviorulez 06/25/16 07:33:32 PM
#3701   If it's really 2% it would still be million_dollar_mafia 06/25/16 03:08:24 PM
#3700   2% I a lot of short interest? LOL The Other Guy 06/25/16 02:58:59 PM
#3699   There is still a large short position million_dollar_mafia 06/25/16 09:58:02 AM
#3698   Well probably nobody wants to short it anymore, Inoviorulez 06/25/16 07:35:50 AM
#3697   Hopefully they get squeezed soon if not already million_dollar_mafia 06/24/16 06:39:31 PM
#3696   BTW, lowest short interest in over a year. The Other Guy 06/24/16 06:06:37 PM
#3695   Short interest down another 8,000 shares to 131,261. The Other Guy 06/24/16 06:04:28 PM
#3694   Good close agreed. I didn't think it would happen. The Other Guy 06/24/16 04:25:56 PM
#3693   Red to green on a bloody day like million_dollar_mafia 06/24/16 03:59:59 PM
#3692   What is the required time to file after The Other Guy 06/23/16 08:47:28 PM
#3691   But if that were the case it would Inoviorulez 06/23/16 08:09:00 PM
#3690   They must have lost interest. Volume is back The Other Guy 06/23/16 02:59:49 PM
#3689   Like I said the other day chat rooms WealthyDreamer 06/23/16 01:22:15 PM
#3688   I'm on board with your take on the Titan V 06/23/16 12:53:18 PM
#3687   Here's my opinion with the recent volume: The merger The Other Guy 06/23/16 12:12:26 PM
#3686   Oh, and did you notice the resistance at The Other Guy 06/23/16 10:50:58 AM
#3685   27% of the outstanding shares have traded the The Other Guy 06/23/16 10:49:40 AM
#3684   I covered for a loss, dd something is WealthyDreamer 06/23/16 09:39:41 AM
#3683   Okay, now something is up. A merger InternetForumUser 06/23/16 09:37:56 AM
#3682   INO has over 10x the shares outstanding that The Other Guy 06/22/16 05:51:30 PM
#3681   That would be nice. I remember the INO Titan V 06/22/16 05:41:18 PM
#3680   Another thing I think it could be is The Other Guy 06/22/16 05:39:09 PM
#3679   Lol I took a starter today, chill. There WealthyDreamer 06/22/16 05:12:46 PM
#3678   He was stopped out at 2.82 so he's million_dollar_mafia 06/22/16 05:12:14 PM
#3677 69k followers, g WealthyDreamer 06/22/16 04:57:25 PM
#3676   The high volume started the other day so Inoviorulez 06/22/16 04:55:29 PM
#3675   Two days before Inovio Pharmaceuticals had announced its Inoviorulez 06/22/16 04:54:31 PM
#3674   Gotta be a leak about something going on. Inoviorulez 06/22/16 04:53:14 PM
#3673   Lol yes I am from 2.70 good luck WealthyDreamer 06/22/16 04:50:23 PM
#3672   Hello there you must be a shorter.... Crawling million_dollar_mafia 06/22/16 04:48:43 PM
#3671   Nope this morning it was pumped by Warrior WealthyDreamer 06/22/16 04:14:19 PM
#3670   What's the old saying? Volume precedes price? The Other Guy 06/22/16 04:11:34 PM
#3669   Highest volume day in company history. 13% The Other Guy 06/22/16 03:26:31 PM
#3668   Possibly. Keep an eye out for any filings The Other Guy 06/22/16 12:41:22 PM
#3667   Must be an institutional investor(s) starting a position. Titan V 06/22/16 10:34:22 AM
#3666   Not sure. PPS seems pretty volatile today. On InternetForumUser 06/22/16 10:16:43 AM
#3665   Day 2 with high volume, no news. Setting The Other Guy 06/22/16 10:08:07 AM
#3664   they been active discussions since may zino 06/22/16 09:19:29 AM
#3663   RXi Pharmaceuticals Provides Strategic Update zino 06/22/16 09:17:08 AM
#3662   those comments are from latest zino 06/22/16 08:03:42 AM
#3661   Extensive pipeline Strong management/BOD/Advisory panel The reason for the low The Other Guy 06/21/16 09:03:42 PM
#3660   Yes. I would like to see a The Other Guy 06/21/16 08:53:38 PM
#3659   they have solid pipeline drugs... zino 06/21/16 08:53:34 PM
#3658   So we are exploring a number of zino 06/21/16 08:48:00 PM
#3657   The volume today was 10x normal average volume. Inoviorulez 06/21/16 08:28:41 PM
#3656   Looking at other stocks in similar position to The Other Guy 06/21/16 06:49:43 PM
#3655   RNAi has been a tough nut to crack Titan V 06/21/16 04:25:25 PM