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RXI Pharmaceuticals Corp (RXII)

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Last Post: 3/31/2015 12:17:36 PM - Followers: 76 - Board type: Free - Posts Today: 4

About RXi Pharmaceuticals

RXi Pharmaceuticals Corporation (OTC: RXII) is a biotechnology company focused on discovering, developing and commercializing innovative therapies based on its proprietary, next-generation RNAi platform.  Therapeutics that use RNA interference, or "RNAi," have great promise because of their ability to "silence," or down-regulate, the expression of a specific gene that may be overexpressed in a disease condition.  Building on the pioneering work of scientific founder and Nobel Laureate Dr. Craig Mello, RXi's first RNAi product candidate, RXI-109, entered into RXi's first human clinical trial in 2012.  RXI-109 targets connective tissue growth factor (CTGF), a key regulatory of fibrosis and scar formation, and is initially being developed to reduce or inhibit scar formation in the skin following surgery.


RXi Pharmaceuticals Corp., has received patent approval for their new experimental breast cancer vaccine which became part of the company's arsenal after acquiring Apthera Inc. in April of this year.
The specific patents in question regard using the vaccine NeuVax with the drug Herceptin which is used in women to slow the production of the HER2 protein in tumors, while NeuVax attempts to make the body's immune system fight off cancerous cells.
According to The Telegram:
"The patents also cover using NeuVax in patients not eligible for Herceptin treatment."
With their patent in place the company plans to begin human tests in early 2012.
According to RXi the patents were developed by Dr. George E. Peoples, director of the Cancer Vaccine Development Program for the U.S. Military Cancer Institute and RXi is leasing the patents for their own work.


This May, RXi Pharmaceuticals Corp. observed two momentous events: The biotechnology company completed its spinoff from Galena Biopharma Inc., and Dr. Geert Cauwenbergh took the helm as president and chief executive officer. The small company's first product, an anti-scarring medication called RXI-109, entered clinical trials this year, and is based on the pioneering work in RNA interference of RXi scientific founder and Nobel Laureate Dr. Craig C. Mello. Dr. Cauwenbergh came to RXi after a long career in pharmaceuticals, most recently as president and chief executive officer of a company he founded, Barrier Therapeutics. What attracted you to come to Worcester? "It was the technology, well, the technology and the chemistry with these people. They're very bright." As a publicly traded company, how do you reconcile the needs of the investors, which are sometimes a short-term desire for profits, with the needs of medical research, which sometimes takes years? "Through business development. Basically what you do as a small biotech is you try to create a big network with people who have interest in various stages of development. ... In two or three years they get antsy and they want to cash in, but at that point in time there will be and there is already a network of business development contacts in place where you can for instance get nondiluted money without having to raise money and go back to the stock market and shareholders by making regional deals or geographic deals ...


Dec 17, 2014 RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301


Press Releases
RXi Pharmaceuticals to Present at Biotech Showcase™ 2013 - December 19, 2012
RXi Pharmaceuticals Announces Initiation of Second Double-Blind Vehicle Controlled Phase 1 Study With Its Anti-Scarring Compound, RXI-109 - December 5, 2012
RXi Pharmaceuticals Announces Pharmacokinetic Results of its Single Dose Phase 1 Study with RXI-109 in Healthy Volunteers - November 15, 2012
RXi Pharmaceuticals Reports Financial Results for the Third Quarter of 2012 - November 14, 2012
RXi Pharmaceuticals to Present at 12th Annual Biotech Symposium - October 16, 2012
RXi Pharmaceuticals Awarded NCI SBIR Funding to Advance Self-Delivering RNAi Technology - October 4, 2012
RXi Pharmaceuticals to Present at 11th Annual BIO Investor Forum - October 2, 2012
RXi Pharmaceuticals Announces Completion of Dosing in Phase 1 Trial for RXI-109 Program - September 24, 2012
RXi Pharmaceuticals Reports Financial Results for the Second Quarter of 2012 - August 15, 2012
RXi Pharmaceuticals Appoints Jeannette Graf MD and Leroy Young MD to its Scientific Advisory Board - July 13, 2012
Share Statistics
Avg Vol (3 month)3: 215,443
Avg Vol (10 day)3: 145,371
Shares Outstanding5: 338m
Float: 53.34M
% Held by Insiders1: 9.01%
% Held by Institutions1: 0.50%


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Current Price
Bid Ask Day's Range
RXII News: RXi Pharmaceuticals Issues Open Letter to Shareholders 12/22/2014 07:02:00 AM
RXII News: RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of En... 12/17/2014 07:02:00 AM
RXII News: RXi Pharmaceuticals to Present New Data in its First Phase 2a Clinical Trial with RXI-109 10/07/2014 07:02:00 AM
News News Alert: RXi Pharmaceuticals's (RXII) CEO Geert Cauwenbergh on Q4 2014 Results - Earnings Call Transcript 03/30/2015 09:48:03 PM
#1738   I read a good explanation of why Tang The Other Guy 03/31/15 12:17:36 PM
#1737   I am out even, minus commissions. GLTA Biggiee 03/31/15 11:14:45 AM
#1736   Thanks...seems to be drifting lower in premarket.....guess we're the submariner 03/31/15 07:47:39 AM
#1735   Conf. call transcript-- with the usual garbled transliterations value1008 03/31/15 01:28:19 AM
#1734   Wet blankets Biggiee 03/30/15 12:37:58 PM
#1733   Market seems to like em too the submariner 03/30/15 08:42:23 AM
#1732   Fins are out this morning Biggiee 03/30/15 07:54:55 AM
#1731   Hoping to grab 1 more block in .70's the submariner 03/28/15 10:39:11 AM
#1730   Got some .74's, we are at bottom Bollie Biggiee 03/28/15 08:53:25 AM
#1729   More good news is coming here.next week 1.00 harmsen 03/27/15 02:34:40 PM
#1728   This looks to be a good move for The Other Guy 03/27/15 09:20:08 AM
#1727   LOL. Good luck waiting for them .50s. Good GMONEY4 03/27/15 09:07:09 AM
#1726   News out. RXi Pharmaceuticals and MirImmune LLC Enter GMONEY4 03/27/15 09:04:21 AM
#1725   Good move..averaging down myself..bought .75's this morning...gl the submariner 03/26/15 09:51:49 AM
#1724   Stopped out @ .92. I'll look to re-enter GMONEY4 03/26/15 09:47:33 AM
#1723   Over a 50% of share sold today were buddygray 03/25/15 07:52:48 PM
#1722   T+3 buddygray 03/25/15 07:09:38 PM
#1721   i follow the risk to feel me alive!!$$ Cubanwinner 03/25/15 07:09:02 PM
#1720   Even an opportunist has to cover? buddygray 03/25/15 07:08:07 PM
#1719   as many here Cubanwinner 03/25/15 07:05:11 PM
#1718   im a opportunistic Cubanwinner 03/25/15 06:38:26 PM
#1717   Are you short? buddygray 03/25/15 06:36:45 PM
#1716   or you will to me Cubanwinner 03/25/15 06:32:24 PM
#1715   Then means more share to cover! Pay me buddygray 03/25/15 06:11:53 PM
#1714   i think this thing are going lower Cubanwinner 03/25/15 05:11:39 PM
#1713   Someone is sitting on over 2,500,000 shorted shares buddygray 03/25/15 04:20:28 PM
#1712   RXII - Loading some down here.... Mark 03/25/15 03:33:26 PM
#1711   BLOOD in the StREET!!!! 50s soon Cubanwinner 03/25/15 03:18:37 PM
#1710   50s coming!!! RED ALERT from this level!!!!!RXii Cubanwinner 03/25/15 03:17:52 PM
#1709   RXII on watch for me as it heads HHHG 03/25/15 02:53:48 PM
#1708   How many cash for RXII?thank you harmsen 03/25/15 02:43:01 PM
#1707   I hope..bought more this morning and awaiting funds the submariner 03/25/15 02:31:20 PM
#1706   And now?Soon 2,00 dollar? harmsen 03/25/15 02:26:13 PM
#1705   Who knew....here's your chance..sub .85 again -( the submariner 03/25/15 10:48:44 AM
#1704   Looks ok. I should've grabbed more. Some nice GMONEY4 03/25/15 08:06:10 AM
#1703   Great grab...gl the submariner 03/25/15 08:01:11 AM
#1702   Grabbed a starter @ .86 GMONEY4 03/24/15 03:54:52 PM
#1701   At what point do the shorts start to The Other Guy 03/24/15 03:05:11 PM
#1700   Dump. Getting cheaper. GMONEY4 03/24/15 02:43:26 PM
#1699   This action makes no sense....smh the submariner 03/24/15 02:27:39 PM
#1698   RXi Pharmaceuticals Provides Positive Update On Phase 2a Inoviorulez 03/23/15 09:52:37 PM
#1697   Pretty common, over the last year, that shorty pistol1p 03/23/15 07:45:23 PM
#1696   40% of todays sell were short sell!lol buddygray 03/23/15 06:36:04 PM
#1695   * * $RXII Video Chart 03-23-15 * * ClayTrader 03/23/15 04:56:03 PM
#1694   I'll wait and see if this holds a GMONEY4 03/23/15 04:27:04 PM
#1693   RXi Pharmaceuticals Reports Positive Advancements in its Dermatology tomsylver 03/23/15 04:24:15 PM
#1692   Someone is shorting the piss out of this!lol buddygray 03/23/15 03:33:40 PM
#1691   Looking to grab a starter. GMONEY4 03/23/15 03:11:40 PM
#1690   Must have been an expectation of recommendation without The Other Guy 03/23/15 03:02:58 PM
#1689   No reason for the pps drop today. pistol1p 03/23/15 12:04:55 PM