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RXI Pharmaceuticals Corp (RXII)

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Last Post: 7/6/2015 5:19:02 PM - Followers: 114 - Board type: Free - Posts Today: 0

About RXi Pharmaceuticals

RXi Pharmaceuticals Corporation (OTC: RXII) is a biotechnology company focused on discovering, developing and commercializing innovative therapies based on its proprietary, next-generation RNAi platform.  Therapeutics that use RNA interference, or "RNAi," have great promise because of their ability to "silence," or down-regulate, the expression of a specific gene that may be overexpressed in a disease condition.  Building on the pioneering work of scientific founder and Nobel Laureate Dr. Craig Mello, RXi's first RNAi product candidate, RXI-109, entered into RXi's first human clinical trial in 2012.  RXI-109 targets connective tissue growth factor (CTGF), a key regulatory of fibrosis and scar formation, and is initially being developed to reduce or inhibit scar formation in the skin following surgery.


RXi Pharmaceuticals Corp., has received patent approval for their new experimental breast cancer vaccine which became part of the company's arsenal after acquiring Apthera Inc. in April of this year.
The specific patents in question regard using the vaccine NeuVax with the drug Herceptin which is used in women to slow the production of the HER2 protein in tumors, while NeuVax attempts to make the body's immune system fight off cancerous cells.
According to The Telegram:
"The patents also cover using NeuVax in patients not eligible for Herceptin treatment."
With their patent in place the company plans to begin human tests in early 2012.
According to RXi the patents were developed by Dr. George E. Peoples, director of the Cancer Vaccine Development Program for the U.S. Military Cancer Institute and RXi is leasing the patents for their own work.


This May, RXi Pharmaceuticals Corp. observed two momentous events: The biotechnology company completed its spinoff from Galena Biopharma Inc., and Dr. Geert Cauwenbergh took the helm as president and chief executive officer. The small company's first product, an anti-scarring medication called RXI-109, entered clinical trials this year, and is based on the pioneering work in RNA interference of RXi scientific founder and Nobel Laureate Dr. Craig C. Mello. Dr. Cauwenbergh came to RXi after a long career in pharmaceuticals, most recently as president and chief executive officer of a company he founded, Barrier Therapeutics. What attracted you to come to Worcester? "It was the technology, well, the technology and the chemistry with these people. They're very bright." As a publicly traded company, how do you reconcile the needs of the investors, which are sometimes a short-term desire for profits, with the needs of medical research, which sometimes takes years? "Through business development. Basically what you do as a small biotech is you try to create a big network with people who have interest in various stages of development. ... In two or three years they get antsy and they want to cash in, but at that point in time there will be and there is already a network of business development contacts in place where you can for instance get nondiluted money without having to raise money and go back to the stock market and shareholders by making regional deals or geographic deals ...


June 9, 2015 RXi Pharmaceuticals Strengthens Intellectual Property Portfolio for Novel RNAi Platform

Dec 17, 2014 RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301

Press Releases
RXi Pharmaceuticals to Present at Biotech Showcase™ 2013 - December 19, 2012
RXi Pharmaceuticals Announces Initiation of Second Double-Blind Vehicle Controlled Phase 1 Study With Its Anti-Scarring Compound, RXI-109 - December 5, 2012
RXi Pharmaceuticals Announces Pharmacokinetic Results of its Single Dose Phase 1 Study with RXI-109 in Healthy Volunteers - November 15, 2012
RXi Pharmaceuticals Reports Financial Results for the Third Quarter of 2012 - November 14, 2012
RXi Pharmaceuticals to Present at 12th Annual Biotech Symposium - October 16, 2012
RXi Pharmaceuticals Awarded NCI SBIR Funding to Advance Self-Delivering RNAi Technology - October 4, 2012
RXi Pharmaceuticals to Present at 11th Annual BIO Investor Forum - October 2, 2012
RXi Pharmaceuticals Announces Completion of Dosing in Phase 1 Trial for RXI-109 Program - September 24, 2012
RXi Pharmaceuticals Reports Financial Results for the Second Quarter of 2012 - August 15, 2012
RXi Pharmaceuticals Appoints Jeannette Graf MD and Leroy Young MD to its Scientific Advisory Board - July 13, 2012
Share Statistics
Avg Vol (3 month)3: 215,443
Avg Vol (10 day)3: 145,371
Shares Outstanding5: 338m
Float: 53.34M
% Held by Insiders1: 9.01%
% Held by Institutions1: 0.50%

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Current Price
Bid Ask Day's Range
#2282  Sticky Note RXII, DD: a solid NASDAQ stock,low market cap ash111 06/25/15 04:36:07 PM
#1762  Sticky Note FBR Capital rates RXII a "Hold" rating with Inoviorulez 04/09/15 01:56:19 PM
#2372   In addition, none of these new institutions want The Other Guy 07/06/15 05:19:02 PM
#2371   RXII will get above $1 easily. Inoviorulez 07/06/15 04:56:25 PM
#2370   P.S.-- i should add that biotech sector may value1008 07/06/15 04:11:37 PM
#2369   Yes, very nice test of support today. I value1008 07/06/15 04:07:50 PM
#2368   another hod into close... ash111 07/06/15 03:55:22 PM
#2367   The company has 180 days to get the The Other Guy 07/06/15 02:03:21 PM
#2366   Do you know how much longer the company InternetForumUser 07/06/15 01:35:15 PM
#2365   need to be $1 or booted from NASDAQ zk12 07/06/15 12:54:49 PM
#2364   So we have predicted $2-$3 pps, but definitely pistol1p 07/06/15 02:15:40 AM
#2363   $RXII Cosmetic use of sd-rxRNA's targeting tyrosinase and wildbullus 07/03/15 05:50:08 AM
#2362   Decent day today. Nice close too! Both the Curt D 07/01/15 07:11:45 PM
#2361   It's down to 71,600 now. Curt D 07/01/15 10:56:54 AM
#2360   Do you see that 91,400 volume bid at Inoviorulez 07/01/15 10:55:20 AM
#2359   Nice to see it coming back to life again. Curt D 07/01/15 10:35:33 AM
#2358   We need more volume but all looks good Inoviorulez 07/01/15 10:33:45 AM
#2357   Trying to show a wall on the ask, Curt D 07/01/15 10:06:08 AM
#2356   Very possible! Volume's coming in a bit better now! Curt D 07/01/15 10:01:31 AM
#2355   This may have something to do with it Titan V 07/01/15 09:51:26 AM
#2354   nice open ash111 07/01/15 09:46:21 AM
#2353   $RXII Yes, I think tomorrow should definitely be StockingUp333 06/30/15 10:10:21 PM
#2352   Agreed. ash111 06/30/15 06:49:49 PM
#2351   I wasn't able to watch level 2, but Curt D 06/30/15 06:44:52 PM
#2350   Nice buys the last couple minutes was nice Virgowhiteguy 06/30/15 04:05:03 PM
#2349   one trade. a good day tmr. i usually ash111 06/30/15 04:02:02 PM
#2348   52 to 49 last second... zk12 06/30/15 04:00:56 PM
#2347   huge reversal into close. ash111 06/30/15 04:00:19 PM
#2346   0.40 by week end zk12 06/30/15 02:46:38 PM
#2345   BTW, I sent a note to RXI IR The Other Guy 06/30/15 01:04:31 PM
#2344   The gap has been closed. It may not The Other Guy 06/30/15 01:01:49 PM
#2343   I am just watching on the sidelines. I InternetForumUser 06/30/15 12:50:43 PM
#2342   Might want to let it flatten out a The Other Guy 06/30/15 12:42:55 PM
#2341   Thanks IFU Titan V 06/29/15 07:26:19 PM
#2340   ~65 Million is correct according to the recent InternetForumUser 06/29/15 07:15:52 PM
#2339   I told IFU 65M based on what Dr. The Other Guy 06/29/15 07:03:57 PM
#2338   65? I thought 57-58. Titan V 06/29/15 06:57:27 PM
#2337   Yes, I am aware of the incorrect information InternetForumUser 06/29/15 05:42:34 PM
#2336   That's not right. It hasn't been updated yet Inoviorulez 06/29/15 05:27:33 PM
#2335   Haven't gotten in yet. I might today InternetForumUser 06/29/15 10:32:17 AM
#2334   IFU, were you able to get the price The Other Guy 06/29/15 10:07:00 AM
#2333   Ugly market day, I still think we are Biggiee 06/29/15 10:00:02 AM
#2332   back to .30's? zk12 06/29/15 09:34:43 AM
#2331   Maybe cause for Pfizer to be looking at The Other Guy 06/28/15 03:04:45 PM
#2330   Why Excaliard showed positve result on EXC001scar reduction wildbullus 06/27/15 09:03:28 AM
#2329   Chart is intact, healthy pullback to confirm new Biggiee 06/26/15 07:58:56 PM
#2328   Yes. They haven't updated the website yet. The The Other Guy 06/26/15 06:35:09 PM
#2327   Okay double checked and ~65 Million is the InternetForumUser 06/26/15 05:34:43 PM
#2326   According to the recent 10-K, there were 36,160,113 InternetForumUser 06/26/15 05:30:33 PM
#2325   Okay. Thanks for the information InternetForumUser 06/26/15 05:10:16 PM
#2324   Thanks IFU. That is not correct. According to The Other Guy 06/26/15 05:09:46 PM
#2323   TOG- Here is a screenshot from the companies website. InternetForumUser 06/26/15 05:02:44 PM