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RXI Pharmaceuticals Corp (RXII)

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Last Post: 7/29/2015 9:02:35 AM - Followers: 111 - Board type: Free - Posts Today: 1

About RXi Pharmaceuticals

RXi Pharmaceuticals Corporation (OTC: RXII) is a biotechnology company focused on discovering, developing and commercializing innovative therapies based on its proprietary, next-generation RNAi platform.  Therapeutics that use RNA interference, or "RNAi," have great promise because of their ability to "silence," or down-regulate, the expression of a specific gene that may be overexpressed in a disease condition.  Building on the pioneering work of scientific founder and Nobel Laureate Dr. Craig Mello, RXi's first RNAi product candidate, RXI-109, entered into RXi's first human clinical trial in 2012.  RXI-109 targets connective tissue growth factor (CTGF), a key regulatory of fibrosis and scar formation, and is initially being developed to reduce or inhibit scar formation in the skin following surgery.


RXi Pharmaceuticals Corp., has received patent approval for their new experimental breast cancer vaccine which became part of the company's arsenal after acquiring Apthera Inc. in April of this year.
The specific patents in question regard using the vaccine NeuVax with the drug Herceptin which is used in women to slow the production of the HER2 protein in tumors, while NeuVax attempts to make the body's immune system fight off cancerous cells.
According to The Telegram:
"The patents also cover using NeuVax in patients not eligible for Herceptin treatment."
With their patent in place the company plans to begin human tests in early 2012.
According to RXi the patents were developed by Dr. George E. Peoples, director of the Cancer Vaccine Development Program for the U.S. Military Cancer Institute and RXi is leasing the patents for their own work.


This May, RXi Pharmaceuticals Corp. observed two momentous events: The biotechnology company completed its spinoff from Galena Biopharma Inc., and Dr. Geert Cauwenbergh took the helm as president and chief executive officer. The small company's first product, an anti-scarring medication called RXI-109, entered clinical trials this year, and is based on the pioneering work in RNA interference of RXi scientific founder and Nobel Laureate Dr. Craig C. Mello. Dr. Cauwenbergh came to RXi after a long career in pharmaceuticals, most recently as president and chief executive officer of a company he founded, Barrier Therapeutics. What attracted you to come to Worcester? "It was the technology, well, the technology and the chemistry with these people. They're very bright." As a publicly traded company, how do you reconcile the needs of the investors, which are sometimes a short-term desire for profits, with the needs of medical research, which sometimes takes years? "Through business development. Basically what you do as a small biotech is you try to create a big network with people who have interest in various stages of development. ... In two or three years they get antsy and they want to cash in, but at that point in time there will be and there is already a network of business development contacts in place where you can for instance get nondiluted money without having to raise money and go back to the stock market and shareholders by making regional deals or geographic deals ...


June 9, 2015 RXi Pharmaceuticals Strengthens Intellectual Property Portfolio for Novel RNAi Platform

Dec 17, 2014 RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301

Press Releases
RXi Pharmaceuticals to Present at Biotech Showcase™ 2013 - December 19, 2012
RXi Pharmaceuticals Announces Initiation of Second Double-Blind Vehicle Controlled Phase 1 Study With Its Anti-Scarring Compound, RXI-109 - December 5, 2012
RXi Pharmaceuticals Announces Pharmacokinetic Results of its Single Dose Phase 1 Study with RXI-109 in Healthy Volunteers - November 15, 2012
RXi Pharmaceuticals Reports Financial Results for the Third Quarter of 2012 - November 14, 2012
RXi Pharmaceuticals to Present at 12th Annual Biotech Symposium - October 16, 2012
RXi Pharmaceuticals Awarded NCI SBIR Funding to Advance Self-Delivering RNAi Technology - October 4, 2012
RXi Pharmaceuticals to Present at 11th Annual BIO Investor Forum - October 2, 2012
RXi Pharmaceuticals Announces Completion of Dosing in Phase 1 Trial for RXI-109 Program - September 24, 2012
RXi Pharmaceuticals Reports Financial Results for the Second Quarter of 2012 - August 15, 2012
RXi Pharmaceuticals Appoints Jeannette Graf MD and Leroy Young MD to its Scientific Advisory Board - July 13, 2012
Share Statistics
Avg Vol (3 month)3: 215,443
Avg Vol (10 day)3: 145,371
Shares Outstanding5: 338m
Float: 53.34M
% Held by Insiders1: 9.01%
% Held by Institutions1: 0.50%

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Current Price
Bid Ask Day's Range
News News Alert: RXi Pharmaceuticals to Webcast Second Quarter 2015 Financial Results on Wednesday, August 12, 2015 07/29/2015 07:02:00 AM
#2282  Sticky Note RXII, DD: a solid NASDAQ stock,low market cap ash111 06/25/15 04:36:07 PM
#1762  Sticky Note FBR Capital rates RXII a "Hold" rating with Inoviorulez 04/09/15 01:56:19 PM
#2419   RXi Pharmaceuticals to Webcast Second Quarter 2015 Financial The Other Guy 07/29/15 09:02:35 AM
#2418   Hopefully a good purchase for you. The Other Guy 07/28/15 10:59:16 PM
#2417   No published buy yet by Sheff, but ....... pistol1p 07/28/15 09:33:07 PM
#2416   got 4k @.4648, rxii looks very promising. I mantisforce 07/28/15 01:24:43 PM
#2415   new here, trying to get 3200 @.46 mantisforce 07/28/15 01:19:35 PM
#2414   Ah, okay. I thought you meant ticker symbol The Other Guy 07/28/15 10:31:55 AM
#2413   Central nervous system. Geert mentioned in one of Titan V 07/28/15 10:27:38 AM
#2412   CNS partnership? Please elaborate. The Other Guy 07/28/15 10:18:50 AM
#2411   Hoping the same. In addition to the two, Titan V 07/27/15 05:32:22 PM
#2410   Still holding strong! Patiently waiting it's been a Virgowhiteguy 07/27/15 04:18:45 PM
#2409   How is everyone doing? Expecting CNS partnership, ocular Titan V 07/27/15 04:10:38 PM
#2408   Biotechs in general have been getting pushed down. The Other Guy 07/23/15 10:00:01 AM
#2407   What is going on... Price keeps on Kev_Sh 07/23/15 08:03:44 AM
#2406   Volume has dried up. RXII is range The Other Guy 07/20/15 11:45:46 AM
#2405   I agree once news hits in a few Inoviorulez 07/18/15 11:25:20 AM
#2404   Lift off imminent this .48-51 zone has been million_dollar_mafia 07/17/15 07:07:37 PM
#2403   On my way back from vacation waiting for The Other Guy 07/17/15 01:16:53 PM
#2402 brancoo0 07/17/15 09:17:36 AM
#2401   nice pre-market move here ... brancoo0 07/17/15 08:51:15 AM
#2400   Anything new here? million_dollar_mafia 07/16/15 01:10:56 PM
#2399   Old news been like that since May 8th Virgowhiteguy 07/14/15 04:30:31 PM
#2398   Nasdaq FSI: Deficient: Issuer Failed to Meet NASDAQ zk12 07/14/15 04:01:39 PM
#2397   $RXII Trade ideas for Monday: Virgowhiteguy 07/11/15 10:19:40 AM
#2396   Why what happened jim1234 07/10/15 07:28:53 PM
#2395   Good timing! Ha Virgowhiteguy 07/10/15 01:09:51 PM
#2394   $RXII recent news/filings stocktrademan 07/10/15 01:05:13 PM
#2393   good shorting more jim1234 07/10/15 09:49:18 AM
#2392   we see again nice big buys coming in brancoo0 07/10/15 09:44:44 AM
#2391   nice article here: brancoo0 07/10/15 09:41:41 AM
#2390   no volume here shorting more jim1234 07/10/15 09:39:12 AM
#2389   thanks for the support on shorting this stock. jim1234 07/10/15 09:31:35 AM
#2388   Yeah, good luck with that! The Other Guy 07/10/15 09:31:04 AM
#2387   I have established a huge short position in jim1234 07/10/15 09:12:44 AM
#2386   Sorry, no. Different company entirely. Some drama on The Other Guy 07/09/15 10:56:00 PM
#2385   The Other Guy, do you mean the RXI-109 wildbullus 07/09/15 09:22:58 PM
#2383   Exactly. They could be on track in December The Other Guy 07/09/15 07:04:30 PM
#2381   OT: if "on track" is quantifiable, why not The Other Guy 07/09/15 06:14:54 PM
#2380   nice big buys are coming in right here... brancoo0 07/09/15 10:52:48 AM
#2379   yeah, that's true ... brancoo0 07/09/15 09:58:57 AM
#2378   Yeah. The PPS seems to be hovering InternetForumUser 07/09/15 09:43:47 AM
#2377   maybe we have a runner here ... brancoo0 07/09/15 09:36:56 AM
#2376   Yesterday down 5% and today down 5%. InternetForumUser 07/08/15 04:28:38 PM
#2375   The general market headwinds have a lot of value1008 07/08/15 11:15:30 AM
#2374   Unusually quiet! The wait begins. The Other Guy 07/08/15 11:06:09 AM
#2373   Awfully quiet around here lately.... the submariner 07/08/15 10:54:28 AM
#2372   In addition, none of these new institutions want The Other Guy 07/06/15 05:19:02 PM
#2371   RXII will get above $1 easily. Inoviorulez 07/06/15 04:56:25 PM
#2370   P.S.-- i should add that biotech sector may value1008 07/06/15 04:11:37 PM
#2369   Yes, very nice test of support today. I value1008 07/06/15 04:07:50 PM
#2368   another hod into close... ash111 07/06/15 03:55:22 PM