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RXI Pharmaceuticals Corp (RXII)

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Last Post: 9/1/2014 8:22:08 PM - Followers: 70 - Board type: Free - Posts Today: 0

About RXi Pharmaceuticals

RXi Pharmaceuticals Corporation (OTC: RXII) is a biotechnology company focused on discovering, developing and commercializing innovative therapies based on its proprietary, next-generation RNAi platform.  Therapeutics that use RNA interference, or "RNAi," have great promise because of their ability to "silence," or down-regulate, the expression of a specific gene that may be overexpressed in a disease condition.  Building on the pioneering work of scientific founder and Nobel Laureate Dr. Craig Mello, RXi's first RNAi product candidate, RXI-109, entered into RXi's first human clinical trial in 2012.  RXI-109 targets connective tissue growth factor (CTGF), a key regulatory of fibrosis and scar formation, and is initially being developed to reduce or inhibit scar formation in the skin following surgery.

RXi Pharmaceuticals Corp., has received patent approval for their new experimental breast cancer vaccine which became part of the company's arsenal after acquiring Apthera Inc. in April of this year.
The specific patents in question regard using the vaccine NeuVax with the drug Herceptin which is used in women to slow the production of the HER2 protein in tumors, while NeuVax attempts to make the body's immune system fight off cancerous cells.
According to The Telegram:
"The patents also cover using NeuVax in patients not eligible for Herceptin treatment."
With their patent in place the company plans to begin human tests in early 2012.
According to RXi the patents were developed by Dr. George E. Peoples, director of the Cancer Vaccine Development Program for the U.S. Military Cancer Institute and RXi is leasing the patents for their own work.

This May, RXi Pharmaceuticals Corp. observed two momentous events: The biotechnology company completed its spinoff from Galena Biopharma Inc., and Dr. Geert Cauwenbergh took the helm as president and chief executive officer. The small company's first product, an anti-scarring medication called RXI-109, entered clinical trials this year, and is based on the pioneering work in RNA interference of RXi scientific founder and Nobel Laureate Dr. Craig C. Mello. Dr. Cauwenbergh came to RXi after a long career in pharmaceuticals, most recently as president and chief executive officer of a company he founded, Barrier Therapeutics. What attracted you to come to Worcester? "It was the technology, well, the technology and the chemistry with these people. They're very bright." As a publicly traded company, how do you reconcile the needs of the investors, which are sometimes a short-term desire for profits, with the needs of medical research, which sometimes takes years? "Through business development. Basically what you do as a small biotech is you try to create a big network with people who have interest in various stages of development. ... In two or three years they get antsy and they want to cash in, but at that point in time there will be and there is already a network of business development contacts in place where you can for instance get nondiluted money without having to raise money and go back to the stock market and shareholders by making regional deals or geographic deals ...

Press Releases
RXi Pharmaceuticals to Present at Biotech Showcase™ 2013 - December 19, 2012
RXi Pharmaceuticals Announces Initiation of Second Double-Blind Vehicle Controlled Phase 1 Study With Its Anti-Scarring Compound, RXI-109 - December 5, 2012
RXi Pharmaceuticals Announces Pharmacokinetic Results of its Single Dose Phase 1 Study with RXI-109 in Healthy Volunteers - November 15, 2012
RXi Pharmaceuticals Reports Financial Results for the Third Quarter of 2012 - November 14, 2012
RXi Pharmaceuticals to Present at 12th Annual Biotech Symposium - October 16, 2012
RXi Pharmaceuticals Awarded NCI SBIR Funding to Advance Self-Delivering RNAi Technology - October 4, 2012
RXi Pharmaceuticals to Present at 11th Annual BIO Investor Forum - October 2, 2012
RXi Pharmaceuticals Announces Completion of Dosing in Phase 1 Trial for RXI-109 Program - September 24, 2012
RXi Pharmaceuticals Reports Financial Results for the Second Quarter of 2012 - August 15, 2012
RXi Pharmaceuticals Appoints Jeannette Graf MD and Leroy Young MD to its Scientific Advisory Board - July 13, 2012

Share Statistics
Avg Vol (3 month)3: 215,443
Avg Vol (10 day)3: 145,371
Shares Outstanding5: 338m
Float: 53.34M
% Held by Insiders1: 9.01%
% Held by Institutions1: 0.50%


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Bid Ask Day's Range
RXII News: RXi Pharmaceuticals Reports Financial Results for the Second Quarter of 2014 08/14/2014 07:05:00 AM
RXII News: RXi Pharmaceuticals Celebrates Expansion of its Operations in Massachusetts 07/02/2014 07:02:00 AM
RXII News: RXi Pharmaceuticals Set to Join Russell Microcap Index 06/25/2014 07:02:00 AM
#1484   Nice week for RXII, up almost 18%. pistol1p 09/01/14 08:22:08 PM
#1483   Inoviorulez, I completely agree with you. If RXI-109 wildbullus 09/01/14 07:33:21 PM
#1482   If you read that info they have actually Inoviorulez 09/01/14 07:23:29 PM
#1481   Renewed Investor Appetite in Biotech Innovation Means Strong wildbullus 08/30/14 01:36:11 PM
#1480   Excellent summary BPP! Always appreciate your DD. Titan V 08/29/14 08:06:04 PM
#1479   Bio, excellent summary, thank you so much! wildbullus 08/29/14 07:08:59 PM
#1478   Reason why RXI-109 Phase 2a will be positive: Inoviorulez 08/29/14 06:56:50 PM
#1477   Nice move up recently. pistol1p 08/29/14 11:37:10 AM
#1476   Nice! Titan V 08/28/14 09:14:45 PM
#1475   Thanks Titan! Yeah, I'm having fun over there Canoepaddler 08/28/14 09:06:12 PM
#1474   Agreed. It should build up very nicely in Titan V 08/28/14 08:49:04 PM
#1473   Confirmed the uptrend today IMO. Volume very good Canoepaddler 08/28/14 08:20:12 PM
#1472   Nice close today. Looking good for next week. Titan V 08/27/14 06:15:36 PM
#1470   Talking to yourself lol bilalali26 08/27/14 05:10:08 PM
#1469   Closed above $2.58 definitively. I think this bodes Canoepaddler 08/27/14 05:07:13 PM
#1464   Stockfrog, is that you? Titan V 08/27/14 02:04:06 PM
#1455   I'm glad you are here, because people don't Inoviorulez 08/24/14 05:11:27 PM
#1454   Dilution and institutional selling recently points to failed piperblumoone 08/24/14 07:19:20 AM
#1453   This pos going down in flames big time. piperblumoone 08/23/14 11:38:30 PM
#1452   RXi Pharmaceuticals Corporation (RXII), a biotechnology company focused pistol1p 08/23/14 01:47:05 AM
#1450   Please post a link, I'd like to read pistol1p 08/23/14 01:38:19 AM
#1449   What a blatant misleading post! cdaniel394 08/22/14 09:50:54 AM
#1448   NEWS: RXI-109 fails in phase 2..,,... piperblumoone 08/22/14 05:09:51 AM
#1447   This pos going down w failed P2 results piperblumoone 08/21/14 11:47:14 AM
#1440   Thank you for your in-depth analysis. pistol1p 08/20/14 08:41:58 PM
#1438   Please. This trash stock is worth a few piperblumoone 08/20/14 12:29:47 PM
#1436   More like 80 cents or 8 cents. Impending piperblumoone 08/20/14 12:27:34 PM
#1435   And I agree as well. piperblumoone 08/20/14 12:25:45 PM
#1434   I totally agree with your assessment. piperblumoone 08/20/14 12:25:21 PM
#1433   This POS stock is worthless. They have nothing piperblumoone 08/20/14 12:24:49 PM
#1432   Ceo RXII news coming to end august BULLISH sedrik 08/20/14 07:16:18 AM
#1431   RXi Pharmaceuticals Expands Clinical Program with Initiation of sedrik 08/20/14 07:15:17 AM
#1430   Couldn't agree more. Good times are not that Titan V 08/15/14 09:11:03 PM
#1429   I added more shares for Monday in RXII Inoviorulez 08/15/14 09:05:32 PM
#1428   $RXII H.C. Wainwright Reiterates Buy On RXi Pharmaceuticals maytepper 08/15/14 12:02:27 PM
#1427   RXII end of year will easy 6-9 sedrik 08/15/14 07:55:02 AM
#1426   Some big name institutional investors in June update Titan V 08/14/14 10:53:03 PM
#1425   Dr. Phillip Frost had even invested in a sedrik 08/14/14 03:57:11 AM
#1424   RXii green Europe Stock today 3% sedrik 08/13/14 08:48:47 AM
#1423   Once the phase 2 results are out wall Inoviorulez 08/07/14 05:31:48 PM
#1422   $RXII represents an undervalued player in the RNA wildbullus 08/07/14 02:25:12 PM
#1421   RXi Pharmaceuticals Expands Clinical Program with Initiation of Inoviorulez 07/30/14 07:57:56 PM
#1420   RXi Pharmaceuticals Expands Clinical Program with Initiation of sedrik 07/30/14 08:21:14 AM
#1419   July 30, 2014, 7:02 a.m. EDT sedrik 07/30/14 08:20:19 AM
#1418   I've been waiting for some liquidity. Hoping to Titan V 07/21/14 05:40:01 PM
#1417   Anyone else adding more shares? I'm about to Inoviorulez 07/21/14 05:23:40 PM
#1416   Sedrik you should join the StockTwits RXII board Titan V 07/20/14 10:58:41 AM
#1415   If CEO can buy 100k shares, that more convincing. wildbullus 07/17/14 06:17:29 PM
#1414   TODAY CEO bought another 1000 shares very good sedrik 07/17/14 10:28:20 AM
#1413   Seekingalpha.. Rxi Pharmaceuticals is only getting started and sedrik 07/17/14 06:20:04 AM