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RXI Pharmaceuticals Corp (RXII)

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Last Post: 5/24/2016 8:56:54 PM - Followers: 137 - Board type: Free - Posts Today: 0

About RXi Pharmaceuticals

RXi Pharmaceuticals Corporation (OTC: RXII) is a biotechnology company focused on discovering, developing and commercializing innovative therapies based on its proprietary, next-generation RNAi platform.  Therapeutics that use RNA interference, or "RNAi," have great promise because of their ability to "silence," or down-regulate, the expression of a specific gene that may be overexpressed in a disease condition.  Building on the pioneering work of scientific founder and Nobel Laureate Dr. Craig Mello, RXi's first RNAi product candidate, RXI-109, entered into RXi's first human clinical trial in 2012.  RXI-109 targets connective tissue growth factor (CTGF), a key regulatory of fibrosis and scar formation, and is initially being developed to reduce or inhibit scar formation in the skin following surgery.


RXi Pharmaceuticals Corp., has received patent approval for their new experimental breast cancer vaccine which became part of the company's arsenal after acquiring Apthera Inc. in April of this year.
The specific patents in question regard using the vaccine NeuVax with the drug Herceptin which is used in women to slow the production of the HER2 protein in tumors, while NeuVax attempts to make the body's immune system fight off cancerous cells.
According to The Telegram:
"The patents also cover using NeuVax in patients not eligible for Herceptin treatment."
With their patent in place the company plans to begin human tests in early 2012.
According to RXi the patents were developed by Dr. George E. Peoples, director of the Cancer Vaccine Development Program for the U.S. Military Cancer Institute and RXi is leasing the patents for their own work.


This May, RXi Pharmaceuticals Corp. observed two momentous events: The biotechnology company completed its spinoff from Galena Biopharma Inc., and Dr. Geert Cauwenbergh took the helm as president and chief executive officer. The small company's first product, an anti-scarring medication called RXI-109, entered clinical trials this year, and is based on the pioneering work in RNA interference of RXi scientific founder and Nobel Laureate Dr. Craig C. Mello. Dr. Cauwenbergh came to RXi after a long career in pharmaceuticals, most recently as president and chief executive officer of a company he founded, Barrier Therapeutics. What attracted you to come to Worcester? "It was the technology, well, the technology and the chemistry with these people. They're very bright." As a publicly traded company, how do you reconcile the needs of the investors, which are sometimes a short-term desire for profits, with the needs of medical research, which sometimes takes years? "Through business development. Basically what you do as a small biotech is you try to create a big network with people who have interest in various stages of development. ... In two or three years they get antsy and they want to cash in, but at that point in time there will be and there is already a network of business development contacts in place where you can for instance get nondiluted money without having to raise money and go back to the stock market and shareholders by making regional deals or geographic deals ...


June 9, 2015 RXi Pharmaceuticals Strengthens Intellectual Property Portfolio for Novel RNAi Platform

Dec 17, 2014 RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301

Press Releases
RXi Pharmaceuticals to Present at Biotech Showcase™ 2013 - December 19, 2012
RXi Pharmaceuticals Announces Initiation of Second Double-Blind Vehicle Controlled Phase 1 Study With Its Anti-Scarring Compound, RXI-109 - December 5, 2012
RXi Pharmaceuticals Announces Pharmacokinetic Results of its Single Dose Phase 1 Study with RXI-109 in Healthy Volunteers - November 15, 2012
RXi Pharmaceuticals Reports Financial Results for the Third Quarter of 2012 - November 14, 2012
RXi Pharmaceuticals to Present at 12th Annual Biotech Symposium - October 16, 2012
RXi Pharmaceuticals Awarded NCI SBIR Funding to Advance Self-Delivering RNAi Technology - October 4, 2012
RXi Pharmaceuticals to Present at 11th Annual BIO Investor Forum - October 2, 2012
RXi Pharmaceuticals Announces Completion of Dosing in Phase 1 Trial for RXI-109 Program - September 24, 2012
RXi Pharmaceuticals Reports Financial Results for the Second Quarter of 2012 - August 15, 2012
RXi Pharmaceuticals Appoints Jeannette Graf MD and Leroy Young MD to its Scientific Advisory Board - July 13, 2012
Share Statistics
Avg Vol (3 month)3: 215,443
Avg Vol (10 day)3: 145,371
Shares Outstanding5: 338m
Float: 53.34M
% Held by Insiders1: 9.01%
% Held by Institutions1: 0.50%

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Current Price
Bid Ask Day's Range
#3596   If only she would respond right? million_dollar_mafia 05/24/16 08:56:54 PM
#3595   Dang million_dollar_mafia 05/24/16 08:56:41 PM
#3594   Short interest up 18k to 152,969 as of The Other Guy 05/24/16 04:14:42 PM
#3593   Anyone contacts IR in RXi Pharmaceutical? Did Tamara wildbullus 05/24/16 02:23:14 PM
#3592   Still Much ado about nothing. Have you Hypocrates 05/24/16 09:21:52 AM
#3591   Yes, halted. Can't you tell by lack of trading? The Other Guy 05/23/16 03:55:57 PM
#3590   News???? Lpl million_dollar_mafia 05/23/16 02:47:05 PM
#3589   Have you not seen the 6 month photos? The Other Guy 05/23/16 11:24:14 AM
#3588   I hope what you said is true, BUT wildbullus 05/23/16 06:48:44 AM
#3587   A merger does not mean a partnership cannot The Other Guy 05/22/16 10:10:13 PM
#3586   My point is there may not have partnerships wildbullus 05/22/16 07:33:19 PM
#3585   Either way the point remains if the company Inoviorulez 05/22/16 06:46:53 PM
#3584   TITAN, The company to be mergered with RXi wildbullus 05/22/16 04:08:43 PM
#3583   Could any of the companies under the "Related Titan V 05/22/16 03:15:58 PM
#3582   Bio, RXi is going to go with merger, wildbullus 05/22/16 01:55:41 PM
#3581   With the merger or partnership with upfront money Inoviorulez 05/22/16 01:37:24 PM
#3580   Lol your one post will not stop momo million_dollar_mafia 05/22/16 12:00:44 AM
#3579   RXi funding will only last to 1H next wildbullus 05/21/16 10:20:30 PM
#3578   Of course, we need volume to get ANY The Other Guy 05/20/16 10:13:02 AM
#3577   Yes... I agree with you other guy on microchips 05/20/16 09:34:43 AM
#3576   TA doesn't show it as a resistance point. The Other Guy 05/20/16 09:24:06 AM
#3575   Also it's major resistance point million_dollar_mafia 05/19/16 07:49:37 PM
#3574   That is the RS value. InternetForumUser 05/19/16 07:07:57 PM
#3573   Why? The Other Guy 05/19/16 05:50:08 PM
#3572   We need a break of 2.60 million_dollar_mafia 05/19/16 05:36:28 PM
#3571   Lol obviously. million_dollar_mafia 05/19/16 04:53:38 PM
#3570   $150 million market cap is not unreasonable for The Other Guy 05/19/16 03:52:31 PM
#3569   $23 target dart lolollol million_dollar_mafia 05/19/16 11:49:19 AM
#3568   Right. How often have we seen Zacks throw The Other Guy 05/19/16 11:15:29 AM
#3567   I believe it is a false jump. Will InternetForumUser 05/19/16 10:25:31 AM
#3566   M&A details being circulated? We have some The Other Guy 05/19/16 09:38:07 AM
#3565   Next week Zacks will recommend to sell. The Other Guy 05/18/16 10:06:30 PM
#3564   Zacks upgraded to strong buy million_dollar_mafia 05/18/16 05:23:52 PM
#3563   Or dilution million_dollar_mafia 05/18/16 11:03:15 AM
#3562   Na seems like there was some degree of million_dollar_mafia 05/17/16 07:03:33 PM
#3561   Even though we are up? Only 5276 shares traded The Other Guy 05/17/16 05:05:54 PM
#3560   Or someone is selling ALOT million_dollar_mafia 05/17/16 03:13:25 PM
#3559   Yeah, if I had my preference, I would The Other Guy 05/17/16 12:39:51 PM
#3558   Phase two results due soon I think million_dollar_mafia 05/17/16 11:53:10 AM
#3557   Tang may not have shorted it directly, but The Other Guy 05/17/16 10:35:22 AM
#3556   Tang didn't short the stock. Tang just kept Inoviorulez 05/16/16 09:24:07 PM
#3555   Do you mean Galena? And what evidence The Other Guy 05/16/16 07:43:05 PM
#3554   Hmmm...dig a little deeper my friend. This Hypocrates 05/16/16 01:23:51 PM
#3553   Down to 177k as of last report. The Other Guy 05/16/16 12:51:47 PM
#3552   Did you mean to post this to a The Other Guy 05/16/16 12:51:22 PM
#3551   Without question this is one of the most Hypocrates 05/16/16 11:29:47 AM
#3550   Shorters gone? What's the short volume?? million_dollar_mafia 05/16/16 11:27:15 AM
#3549   Not saying that the company will be sold The Other Guy 05/16/16 08:48:08 AM
#3548   But management knows the value of the company Inoviorulez 05/15/16 11:45:31 PM
#3547   If you wanted to acquire a company with The Other Guy 05/15/16 10:43:18 PM