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OphthaliX Inc. (OPLI)

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Last Post: 11/16/2016 8:23:46 AM - Followers: 5 - Board type: Free - Posts Today: 0
CF101 is currently being developed by OphthaliX to treat three ophthalmic indications: dry eye syndrome; glaucoma and uveitis. A phase III dry eye syndrome study is currently ongoing, under a US IND, in the US, Europe and Israel. A phase II Glaucoma study is currently on conducted in Europe and Israel. Preparatory work for phase II in Uveitis is underway.

Dry Eye Syndrome 
CF101 has successfully completed a Phase II study in dry eye syndrome, meeting its primary endpoints and demonstrating the drug`s ability to improve signs of ocular surface inflammation in moderate-to-severe dry eye syndrome patients. CF101 was well tolerated and exhibited an excellent safety profile with no serious adverse events. The study results were published in ‘Ophthalmology’, which is one of the leading journals in the ophthalmology field 10.

Glaucoma 
Measurements of intraocular pressure (IOP) in the Phase II dry eye syndrome trial, monitored for safety assessment in patients with normal baseline values, showed a statistically significant reduction in IOP in the tested subjects. This observation indicated that CF101 may also have potential as a treatment for glaucoma and led to our current Phase II clinical trial in glaucoma.

Uveitis 
Recent animal data emerging from studies carried out in collaboration with Dr. Rachel Caspi at the National Eye Institute (Betesda, US), have demonstrated that CF101 is effective in suppressing ocular inflammation in experimental model of uveitis, indicating that the anti-inflammatory activity of CF101 can be beneficial in the treatment of uveitis, a chronic, idiopathic, sight-threatening disease. The results of this study were published in the ’International Journal of Molecular Medicine’ 11.

 

http://www.ophthalix.com/?KPageId=64
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#67   In July 2016, we released top-line results from midastouch017 11/16/16 08:23:46 AM
#66   In June 2016, Can-Fite plans to report data midastouch017 05/27/16 09:24:35 AM
#65   The Phase II trial is being conducted in midastouch017 05/05/16 09:58:44 AM
#64   Can-Fite’s CF101 Granted Patent in Japan for Intraocular midastouch017 12/17/15 09:09:38 AM
#63   Can-Fite Subsidiary, OphthaliX, Announces Completion of Patient Enrollment midastouch017 12/07/15 08:53:54 AM
#62   Item 1.01 Entry into a midastouch017 08/28/15 01:50:41 PM
#61   OphthaliX Launches Updated Website to Reflect Proposed Acquisition midastouch017 07/14/15 03:28:09 PM
#60   OphthaliX Signs Definitive Agreement to Acquire Improved Vision midastouch017 06/19/15 09:28:19 AM
#59   Planned Acquisition of Medical Device Company by Can-Fite Subsidiary midastouch017 05/29/15 09:17:49 AM
#58   Can-Fite Bio to acquire ocular device developer midastouch017 05/04/15 11:24:48 AM
#57   Ophthalix has signed a non-binding term sheet to midastouch017 05/04/15 09:18:15 AM
#56   Can-Fite subsidiary, OphthaliX, Signs Term Sheet to Acquire midastouch017 05/04/15 09:05:22 AM
#55   H2 2015 midastouch017 03/28/15 07:23:02 AM
#54   We are focused on the development of CF101 midastouch017 03/28/15 07:08:37 AM
#53   Form 10-K for OPHTHALIX, INC. midastouch017 03/28/15 07:06:42 AM
#52   In the footsteps of CANF! midastouch017 03/19/15 01:03:04 PM
#51   OpthaliX, Inc., is currently testing CF101 in a midastouch017 03/17/15 04:20:31 PM
#50   Second Part of the Glaucoma Phase II study midastouch017 12/15/14 08:33:25 AM
#49   With CANF on the sharp rise midastouch017 12/01/14 09:03:06 AM
#48   Over $1 today? midastouch017 11/26/14 06:05:31 AM
#47   I don't have PM. It was more tk2007 11/24/14 02:18:09 PM
#46   touched bottom earlier today midastouch017 11/24/14 01:36:30 PM
#45   I think it has touched bottom earlier today. tk2007 11/24/14 01:30:39 PM
#44   Crazy price swings today!!! midastouch017 11/24/14 01:24:42 PM
#43   just like Can-Fite midastouch017 11/23/14 08:45:31 AM
#42   This one is still undiscovered just like Can-Fite... tk2007 11/21/14 03:40:36 PM
#41   Obviously not! midastouch017 11/21/14 10:19:14 AM
#40   Will the price and volume midastouch017 11/21/14 08:32:19 AM
#39   In addition to the very large available markets, midastouch017 11/20/14 02:49:23 PM
#38   OPLI follows CANF!!! midastouch017 11/20/14 01:53:55 PM
#37   Can-Fite Subsidiary OphthaliX Provides an Update on its midastouch017 06/09/14 10:33:37 AM
#36   Can-Fite to Present at the 9th International Congress midastouch017 03/25/14 07:25:30 AM
#35   Can-Fite: Phase II Study Protocol to Treat Patients midastouch017 03/17/14 10:22:12 AM
#34   Can-Fite Announces the Addition of A Key Opinion midastouch017 03/04/14 05:35:03 AM
#33   Can-Fite Granted Patent on the Manufacturing of CF101 midastouch017 02/25/14 01:29:57 PM
#32   Can-Fite Provides Update on Key Milestones for 2014 midastouch017 02/18/14 08:58:29 AM
#31   Can-Fite Provides Update on Key Milestones for 2014 midastouch017 02/18/14 08:58:21 AM
#30   Can-Fite Comments on Global Rheumatoid Arthritis Market Opportunity midastouch017 02/11/14 12:55:17 PM
#29   Can-Fite to Present New Clinical Data from Further midastouch017 01/13/14 09:21:27 AM
#28   OphthaliX to Retrospectively Analyze Phase III Dry Eye midastouch017 12/31/13 09:06:38 AM
#27   positive side under 10k vol* [SMART MONEY] 12/30/13 04:04:16 PM
#26   OPLI 1.25 -4.25 (- 77.27% ) [SMART MONEY] 12/30/13 04:04:07 PM
#25   A lesson to learn with every trade. michaeldouglas 12/30/13 03:29:26 PM
#24   Can-Fite BioPharma announces top-line results of Phase III mlkrborn 12/30/13 10:10:21 AM
#23   no vol* yet= odd [SMART MONEY] 12/30/13 07:17:02 AM
#22   :-(:-(:-( midastouch017 12/30/13 07:09:48 AM
#21   $3X$6.13 p/m [SMART MONEY] 12/30/13 06:12:56 AM
#20   News Alert: OphthaliX Announces Top-Line Results of Phase [SMART MONEY] 12/30/13 06:11:33 AM
#19   The manner in which OPLI and CANF are midastouch017 12/26/13 03:30:32 PM
#18   First sign of life today, midastouch017 12/20/13 12:28:15 PM
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