NxStage Medical, Inc., a medical device company, engages in the development, manufacture, and marketing of systems for the treatment of end-stage renal disease and acute kidney failure in the United States. The company's primary product includes NxStage System One, a portable hemodialysis system, which is designed to provide physicians and patients flexibility in prescribing and delivering hemodialysis therapy. It offers its products primarily to dialysis clinics, as well as other hospitals that treat acute kidney failure and fluid overload. The company was incorporated in 1998 as QB Medical, Inc. It later changed its name to NxStage Medical, Inc. The company is headquartered in Lawrence, Massachusetts.