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MultiCell Technologies (MCET)

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Last Post: 5/23/2016 2:09:56 PM - Followers: 542 - Board type: Free - Posts Today: 0

 
MultiCell Technologies, Inc. (MCET)

(U.S. Reporting: SEC Filer) 

Outstanding shares 5,000,948,700 as of Jul 8, 2015 

Office: (401) 762-0045  |  Email: info@multicelltech.com

http://www.MultiCellTech.com

(This "Intro Box" is NOT maintained by MultiCell Technologies and is intended solely as a quick information source on ihub.  For more detailed, up-to-date information on MultiCell Technologies,  please go the company website.)


Partners

AmarinCorningPhizer

 

MultiCell inks R&D agreement with Oxis Biotech

MultiCell Technologies (OTCPK: MCET) subsidiary MultiCell Immunotherapeutics enters into a research and development and product license agreement with Oxis Biotech (OTCQB: OXIS) to create three novel antibody-drug conjugates (ADCs) based on Oxis' lead drug candidates and MultiCell's proprietary ADC platform technology. The ADCs will be targeted for the treatment of triple-negative breast cancer and multiple myeloma and associated osteolytic lesions.

Under the terms of the agreement, Oxis will pay MultiCell a license fee of $500K, up to $12.75M in clinical development milestones and a royalty of 3% on net sales. Oxis will also reimburse MultiCell up to $1.125M in development costs. MultiCell grants Oxis an option to purchase manufacturing rights to the three ADCs upon the payment of an additional $10M.

MultiCell retains all rights to its ADC platform for all indications and is free to pursue its own drug development programs and to partner with other firms.



Therapeutic Pipeline

MultiCell Technologies’ portfolio of lead drug candidates is in various stages of preclinical and clinical development:

MCT-125, a Phase 2 therapeutic candidate for the treatment of PMSF which has demonstrated efficacy in a 138 patient Phase IIa clinical trial.
MCT-465, a preclinical synthetic dsRNA therapeutic candidate and potent immune enhancer for the treatment of solid tumor cancers such as those expressing TLR-3.
MCT-475, a discovery stage dsRNA therapeutic candidate with tumor cytolytic properties for the treatment of certain cancers.
MCT-485, a discovery stage dsRNA therapeutic candidate for the treatment of certain cancers.

 Therapeutic Candidate  

   Indication    

    Discovery Optimization    

    Preclinical Development    

    Phase 1    

    Phase 2/b   

    Phase 3    

 MCT-125 

PMSF

yes yes yes yes  

MCT-465

Cancer

yes yes      

MCT-475

Cancer

yes yes      

MCT-485

Cancer

yes yes      


Patent Portfolio of MultiCell Technologies, Inc., MultiCell Immunotherapeutics and majority-owned subsidiary, Xenogenics. Patents already published which can be found in the public domain.


MultiCell Technologies, Inc. Corporate Headquarters


68 Cumberland Street, Suite 301
Woonsocket, RI 02895


MultiCell Technologies, Inc. is a clinical-stage biopharmaceutical company developing novel therapeutics and discovery tools that address unmet medical needs for the treatment of neurological disorders, hepatic disease and cancer.

Our therapeutic development platform relies on several patented technologies used to: (i) isolate, characterize and differentiate stem cells from human liver, or (ii) control the immune response at transcriptional and translational levels through dsRNA-sensing molecules such as Toll-like receptor (TLR), RIG-I-like receptor (RLR), and MDA-5 signaling, or (iii) generate specific and potent immunity against key tumor targets through a novel immunoglobulin platform technology, or (iv) modulate the noradrenaline-adrenaline neurotransmitter pathway.

Our most advanced lead drug candidate, MCT-125, is an oral small molecule drug combination which targets the noradrenaline-adrenaline neurotransmitter pathway for the treatment of primary multiple sclerosis-related fatigue (PMSF). Primary multiple sclerosis-related fatigue (PMSF) affects over 70% of all persons with multiple sclerosis (MS). MCT-125 has demonstrated efficacy in a 138 patient Phase 2a clinical trial for the treatment of PMSF.

While significant progress has been made in developing cancer therapies that result in tumor regression, the control of cancer over a longer interval and especially of metastatic disease, remains a key goal. MultiCell is also developing novel therapeutics for the treatment of cancer. MCT-465, MCT-475 and MCT-485 are the first of a family of prospective cancer therapeutics based on the use of our patented therapeutic antibody and synthetic dsRNA technologies. MCT-465, a potent immune enhancer, is indicated as an cancer adjuvant therapy alone or combined with currently available or novel therapies. MCT-465 can also be used with our MCT-475 antibody therapeutic for the treatment of various cancers such as breast carcinoma. MCT-485, a cytotoxic agent, is a novel synthetic dsRNA with therapeutic properties distinct from those of MCT-465, and is indicated for the treatment of certain cancers. MCT-465 is in early-stage preclinical development, and MCT-475 and MCT-485 are in the discovery optimization stage of development.

The role liver stem cells play in the carcinogenic process has recently led to a new hypothesis that hepatocellular carcinoma arises by maturation arrest of liver stem cells. MultiCell is developing therapeutic product opportunities specifically targeting the treatment of hepatocellular carcinoma and intrahepatic bile duct cancer by leveraging our synthetic dsRNA and antibody therapeutic platforms against cancer stem cells. MultiCell owns exclusive rights to two issued U.S. patents (6,872,389 and 6,129,911), and several corresponding issued and pending patents and patent applications related to the isolation and differentation of liver stem cells.


Find us on Google Maps      http://www.facebook.com/MCET.OB  
 


 Management and Board of Directors


Barbara (Corbett) Newmin - Investor Relations



W. Gerald Newmin, Chairman and Chief Executive Officer



Dr. Steve Chang Ph. D., Director




Grant Miller, Director

 


Alan Tuchman, M.D.

Thomas A. Page, Director

Edward Sigmond, Director



 

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MCET News: Statement of Ownership (sc 13g) 02/16/2016 06:20:13 AM
PostSubject
#41332   I don't really think they have done anything simon wagstaff 05/23/16 02:09:55 PM
#41331   I find it amazing how Barbara Newmin (HEAD Dip66 05/23/16 11:55:48 AM
#41330   2nd that ctvette2003 05/20/16 11:15:21 AM
#41329   I think you should spend the $2000.00 for simon wagstaff 05/20/16 09:28:05 AM
#41328   2016 Pipeline of Hepatitis C Market Covering 84 Companies TPX 05/20/16 07:15:02 AM
#41327   Goodness, now there is a reliable source! simon wagstaff 05/19/16 11:18:02 AM
#41326   PR Newswire redsox17 05/19/16 08:57:10 AM
#41325   La Jolla must not be happy owning 10%+/- Dip66 05/17/16 04:00:01 PM
#41324   I started here. Good education not to trust Latinachica 05/16/16 09:35:48 PM
#41323   I will just point out once again that simon wagstaff 05/10/16 06:44:21 AM
#41322   Looks like they just take are money and ferenc 05/09/16 09:36:19 AM
#41321   Barbara, Gerald or Steve come on give me The Future 05/04/16 05:36:27 PM
#41320   News is in the pipeline The dead cat bouncer 05/04/16 01:02:52 PM
#41319   They don't report anymore? How come ? ferenc 05/04/16 08:33:09 AM
#41318   HaHaHaHa! Wrong board I think. simon wagstaff 05/03/16 07:23:49 AM
#41317   Yeah, after a 1:10000 RS. Happened to me andre b 05/02/16 05:53:01 PM
#41316   This could easily go to $1.00 just watch WtdoIknow 05/02/16 03:32:47 PM
#41315   What hope? They have deleted just about everything simon wagstaff 04/29/16 09:13:36 AM
#41314   MCET, can you at least throw us a The Future 04/28/16 05:42:49 PM
#41313   Interesting activity on Level II. 6.3M in volume. Dip66 04/22/16 12:15:42 PM
#41312   What happened? Feels like a ghost town. Long The Future 04/21/16 11:37:17 PM
#41311   Entire portfolio is green today, MCET red, as Dip66 04/18/16 02:55:07 PM
#41310   Posting on MultiCell's FB page is like using SnapChat. mrroundtree 04/15/16 04:46:46 PM
#41309   Flip the switch and get this going! Dip66 04/15/16 10:47:49 AM
#41308   ..come on mcet, you can do it, mark5050 04/15/16 09:51:22 AM
#41307   Yes, authorized shares total 10 billion I believe. simon wagstaff 04/14/16 10:33:28 AM
#41306   They already tried once, don't matter just keep #1 PATRIOTS_RSOX FAN 04/13/16 08:26:48 PM
#41305   They will not RS this. To many personal Dip66 04/13/16 08:21:23 PM
#41304   They posted that on FB, don't shoot the #1 PATRIOTS_RSOX FAN 04/13/16 05:24:06 PM
#41303   I'm not buying it they are very well Dip66 04/13/16 05:21:32 PM
#41301   Can this be any funnier? #1 PATRIOTS_RSOX FAN 04/13/16 08:38:46 AM
#41300   and MS fatigue . . bontooth 04/12/16 02:38:22 PM
#41299   And HIV, and Bird Flu, and MS and..... simon wagstaff 04/12/16 07:38:09 AM
#41298   And this company was suppose to cure cancer? Dip66 04/11/16 09:29:35 PM
#41297   They sure deleted a bunch of posts there. simon wagstaff 04/11/16 02:28:38 PM
#41296   MultiCell has been basically exposed on their FB Dip66 04/11/16 12:36:47 PM
#41295   "They are actively doing research in Pittsburgh." simon wagstaff 04/08/16 10:15:54 AM
#41294   I'm convinced MultiCell is artificially inflating their price Dip66 04/07/16 08:25:25 PM
#41293   Because after going to their office myself I ctvette2003 04/07/16 03:16:32 PM
#41292   Look ,sorry we are all not happy with ferenc 04/07/16 03:08:59 PM
#41291   What if they moved? Well for starts, I ctvette2003 04/07/16 02:32:25 PM
#41290   What it they moved? They are actively The dead cat bouncer 04/07/16 02:25:52 PM
#41289   Obviously you have t followed this board or ctvette2003 04/07/16 10:17:16 AM
#41288   I wish everybody as smart as you... ferenc 04/07/16 10:15:54 AM
#41287   Well some moron just wasted $500 ctvette2003 04/07/16 09:56:13 AM
#41286  Restored Getting mighty testy over on the MCET Facebook simon wagstaff 04/06/16 08:35:10 AM
#41285   It was a very strange deal. It went simon wagstaff 04/05/16 10:56:02 AM
#41284   MultiSmell was sitting back banking on OXIS to Dip66 04/05/16 10:17:25 AM
#41283   I removed those posts. I am not letting Dip66 04/05/16 10:15:19 AM
#41282   Oh puleeze! Patent on MCT-125 expires in just simon wagstaff 04/05/16 08:20:04 AM
PostSubject