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This guy really said between 2 cents and 5 dollars lmao
I think it’s more likely that he invented immunity DS silkworms that consume waste plastic instead of mulberry leaves. Just think about how rich you’re going to be. Why partner with somebody when you can do it better by yourself? Somehow the Air Force is involved in all of this too but I haven’t figured out how yet.
Maybe KT was hinting at a future partnership or venture of some sort. 🤷♂️.
"If Thompson makes a half ton of silk in June, we might see products by Christmas. But 18 months to market is also a possibility."
smh
Time to market depends on if/when the first metric ton of silk appears, what dilution ratios they employ, and the kind of products they want to make.
A metric ton of silk in a 90%/10% blend makes 10 tons of material. They could spin up a limited edition hoodie in about 6 months. A limited edition silk tie would be a little faster.
Lots of uncertainty in predicting the possibilities. If Thompson makes a half ton of silk in June, we might see products by Christmas. But 18 months to market is also a possibility.
Stay tuned…
Anyone hear anything lately about:
Production
Revenues
Profits??!?
“It is an indication of what is happening like it or not.”
It is an indication of what happened in the past. Anybody speaking of the past on this board will usually get lam-blasted by the rah rah crowd.
You say you come here to learn but all you do is insult any poster that tries to add any sensible input. All you’re really looking for here is support for your overly optimistic expectations and if you don’t get it then you just throw insults.
I’m not here expecting a big home run here like a lot of folks on this board. I’ve actually ran the numbers and looked at various scenarios that could make this company profitable. I’m not buying the snake oil ‘Holy Grail’ crap others continually spew here but it could be a decently profitable business if KT ever figures out what he’s doing.
Also, Bingo is just as bad as this board. Those old ladies don’t like it there when you know what you’re doing either.
15 years later, It's still produced cocoon.
It is an indication of what is happening like it or not. Anything positive or has potential to be so must be questioned and analyzed by you of all people. I admit that I am an amateur and come here on and off during the day to see what has transpired and learn something. Maybe it is time to take a break and get back into Bingo once again. It is Friday you know and the Knights of Columbus Hall is getting ready for a big night. Good Luck, let's not be Bingoless too!
SZ, hearing anything lately?
Should be a steady increase in interest if the PRs continue on the trajectory they are currently on..
GLTA
W2R
“If clues were sand and we gave you a grain each time to educate you...the Sahara Desert would be out of sand in a year.”
A guys looking for clues and you give him poetry. Thanks for verifying that you don’t have a clue either. You could have done that by just not responding and saved us all some time.
“ Comparative Relative Strength analysis shows that this issue is outperforming the S&P 500. (My emphasis)”
And you think that I’m the one that’s clueless. It’s an AI generated blurb from Schwab and is pretty much useless unless you’re into useless after the fact stats.
First time I believe haven’t seen any trades go through in the first few
minutes of trading.
Patrik
Since the beginning of the new year Kim started bi-weekly then weekly PR's and the stock price is just shy of a 200% gain (.033 to .094). It has not dropped below .068 in the last three months which maintains a doubling of the price. I can't imagine Kim not keeping some sort of weekly info release since he must know he has created this anticipation. My guess is that he has the goods since his MO has been that he releases news a bit after the fact. You don't have a three month "pump" as the naysayers like to call it. Besides that I always go back to the fact that Kim is not the only one whose reputation is on the line by him starting this predictable flow of information. The big names in the sericulture game and those in the local government and business groups would not be going along so willingly if this was a pump and dump scheme. KBLB is showing strength on these releases and I believe that this will continue and the subject of each will get better and stronger with each release.
“This is the part that really caught my eye. Of course, it leads directly into the link below to a PR from Kraig that was readily dismissed w/o much fanfare.”
I don’t know why you would think a competitive source of spider silk protein would get any fanfare on this message board. They are making spider silk using waste plastic. They’re not making plastic out of spider silk. I still haven’t got a clue why KT thought that was worth a PR other than to pat himself on the back saying “Look, we’re kinda in the same business as this other outfit.”
And then he pulls it out of his … ‘hat’ …
https://www.sciencefriday.com/articles/silk-history-technology-book-excerpt/
It’s a nice, but flawed, excerpt from a book I’ll probably buy. I don’t have a single book on silk. So, it’ll be a welcome addition. Her writing flows nicely and in this excerpt lays out some really interesting attributes of silk itself. For example, spiders transform sound into energy and the transformation of pheromones. One silk strand is one-thousandth of a human hair, bullet proof vest in Chicago in the 19th century, self-healing biopolymers and its’ adhesiveness underwater. Spider silk is massively adaptable w/ applications across the board.
She mentions Maria Sybilla Merian (https://www.britishmuseum.org/collection/animals/maria-sibylla-merian-pioneering-artist-flora-and-fauna), a pioneer if there ever was. Ms. Prasad couldn’t resist taking a potshot by writing, “who showed the men of science, by example, that it was vital to move beyond studying their dead insects pinned to cards”. Really necessary?
And then she brings up the gag inducing goat enthusiast Randy Lewis. Oof! She recovers by citing England’s University of Oxford, Prof Fritz Vollrath work on repairing damaged cartilage. Or Prof Fiorenzo Omenetto’s SilkLab at Tufts University, Boston work on repairing vocal chord paralysis. Evidently, it is already approved for vocal chord repair. Didn’t know that.
Her citing Louis Pasteur is a major oversight. “Silkworm studies gave Louis Pasteur a robust body of evidence for contagion, from which the study of human diseases would later benefit.”. The author needs to do some more homework as there is significant controversy surrounding Mr. Pasteur and his presumed ‘work’. Notably in relation to Antoine Béchamp. Book: Béchamp or Pasteur? By Ethel Hume. TPTB (shouldn’t be really) promoted Pasteur in very much the same way they promoted Einstein (vs. Max Planck, for e.g.). Both characters are worth a second, more discerning, look into their alleged “discoveries”.
This is the part that really caught my eye. Of course, it leads directly into the link below to a PR from Kraig that was readily dismissed w/o much fanfare. PRs cost money. CEO Thompson was making a point. Given this quote, that PR takes on new meaning. Think about the ‘plastics’ market. The mind reels. Lots of ‘green’ in plastics.
Silk, The Ancient Material With High-Tech Possibilities
“Silk: A World History” describes the unique qualities of silk that make it a sustainable material with a wide variety of applications.
April 26, 2024
SCIENCEFRIDAY LINK
We could be in the dollars by this summer!
If all goes well. Contracts, metric tons, produced finished products.
Kblb has already been supplying “samples” to different entities for over a year now. All that would need to be done is incorporating BAM silk into these designs.
The Risk vs Reward favors the longs at the moment. By the end of 2024, the share price should be between 2 cents - 5 dollars per share. Being a Kong I am excited to see that spread.
This could finally be the year.
“I haven't checked but I'm certain you started this stuff.”
So in other words, you’re just spouting crap about stuff you don’t know anything about like usual.
I haven't checked but I'm certain you started this stuff. I can finish it now. Last post to you for awhile. Be unreasonable by yourself.
Who said I was trying to fix you? I couldn’t care less about what you dish out. You’re the one that asked me a question and demanded an answer.
You get back what you dish out. As I said can't fix stupid.
What mission would that be? Trying to have an intelligent conversation on this board without being insulted?
Remember when I remind you that you and your mission have failed. It's coming.
That’s funny. I got it from you.
Is it fair to say final end products made with KBLB’s spidersilk are 6 to 12 months away? Or are we thinking 12 to 18 months away, of more? If their prediction that they would hit metric ton by the end of the year comes true, I am leaning toward 6 to 12 months away.
Remember when George Costanza had the Yankees switch their uniforms on Seinfeld? Well, it just inspired a new meme…
“ At least I know that this board was created for discussing the company KBLB and not its posters.”
From your earlier post today:
“ in cases where the male was incompetent or suffered from premature ejaculation like a lot of investors in this stock do.”
Try not being so hypocritical all the time…you want to chastise and pretend to rise above, when the truth is, you are also doing the same thing you are complaining about…
I know it’s difficult for you, but make an effort to be reasonable…
At least I know that this board was created for discussing the company KBLB and not its posters. Just because you’re not smart enough to add any useful information doesn’t mean others aren’t. Sorry if that makes you feel so inferior that the only thing you can do is resort to character bashing or putting out useless ‘Go Team’ posts like a lot of the other rah rah posters.
"Just take today for example. 439K SELLS 34k buys"
its a miniscule amount of shares...the pps "crashed" from .096 to .094...lol
are you even trying??
<< watch out for the crucial trading moment of the day where the orchestrated "shocking seller(s)" manipulate the share price in a manner that the positive chart building picture is "killed" ! >>
That is a crock of BS.
Just take today for example.
439K SELLS
34k buys
It wasn't even close.
The "crucial trading moment of the day" was the opening bell. LOL.
As I have said can't fix stupid. You are an excellent example.... and I agree with Mojo in his opinion about you and a clown face. You're right on top of your game.
So why would you bother asking me a question and expect an answer? Don’t you have enough shit of your own? You can come pump my septic tank if you want.
"Ben isn’t sending me any secret coded messages. Hope that helps you."
It's hard to believe that. At times (most of the time) you act as if you know lots of shit all by yourself. And most of the time I agree you... you do know lots of shit.
Trolling?
Or harassing?
I get the same info from the company that you do. I decipher that info based on my own judgement and experience with the company. You can decipher it however you wish. Ben isn’t sending me any secret coded messages. Hope that helps you.
Ramping up?
Or doubling up?
Please read my reply which was a question... stated again below
"Did you read somewhere or hear that included all the worms shown in the picture, or is that an assumption?"
That means did you assume your statement or read or hear what you said?????
What are you assuming?
I am so funny. Ha ha. I bet you wish you were this comical.
“I see you haven’t made it past 2nd grade if that’s all you can come up with.”
I commented on your post in the same manner you wrote it…
You are essentially clowning yourself…
Lol
And yet the pps is over 3 times higher than just a few months ago…AND HOLDING…
try again…lmao
“I expected they would have shipped far more eggs over than what they appear to have to start the trials and production with. Not using enough female lines is how you end up getting too inbred which is one of the problems they had with the previous DS worms. ”
Oh no!…maybe we should alert Dr Kumar of your conclusions!…lol
" I expected they would have shipped far more eggs over than what they appear to have to start the trials and production with. Not using enough female lines is how you end up getting too inbred which is one of the problems they had with the previous DS worms."
Did you read somewhere or hear that included all the worms shown in the picture, or is that an assumption?
I see you haven’t made it past 2nd grade if that’s all you can come up with.
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Moderators MU_Redskin1 gimmegimmeminemine TRUISM EOT WebSlinger |
Email: corporate@KraigLabs.com
KRAIG LABS WEBSITE FOR INVESTORS
Quarterly and Annual Reporting to the SEC is available on the Company's Website and EDGAR.
* Financial Statements * SEC Filings *
Outstanding Shares as of January 12, 2023
For issues or questions relating to share certificates or the transfer of securities please contact the company's transfer agent:
Olde Monmouth Stock Transfer Co., Inc.
200 Memorial Pkwy.
Atlantic Highlands, New Jersey 07716
Phone: (732) 872-2727
(since August 14, 2013)
Kraig Biocraft Laboratories, Inc. (KBLB) is the first company with a commercially feasible spidersilk to be mass produced.
Kraig Labs is a biotechnology company focused on the development of commercially significant high performance polymers and technical fibers. Kraig Lab's focus has been on the production of a transgenic silkworm incorporating specific gene sequences from the golden orb weaving spider. These specific gene sequences inserted are to enable the silkworm to spin a new recombinant fiber which incorporates spider silk proteins. With the scientific breakthrough announced on September 29, 2010, Kraig Labs is now working to commercialize the transgenic silkworms to compete in the garment industry silk market. The value for the chinese raw silk market alone is 3-5 billion per annum. With the creation of 20 seperate transgenic silkworms, all with unique properties, Kraig Labs is now working at an accelerated pace to build upon their first generation transgenic organisms to develop their second generation of transgenic silkworm incorporating spider silk proteins. The scientists nearly doubled the strength of the silkworm with these specific spider gene insertions. Their second generation of transgenics are expected to be complete in 2011. These second generation organisms are to be compared with the strength, flexibility and resiliency of the native spider in which the gene sequences are derived from. These fibers which will match the strength of spider silk are expected to compete in the technical textiles market valued in excess of 120 billion per annum. The 3rd generation organisms are currently in the planning phase. These organisms are expected to spin fibers exceeding the strength of native spiders and may incorporate gene sequences that release an antibiotic, or to help reduce scarring with use in bandages.
Kraig Biocraft Laboratories has a sponsored research and development program with the University of Notre Dame, and the University of Wyoming. The genetic work is occurring at the University of Notre Dame, headed by Dr Malcolm Fraser, Phd. The gene sequences are derived from Dr. Randy Lewis's(University of Wyoming) patented gene sequences of the golden orb weaving spider. Kraig labs is paying for all expenses incurred for this research and development program, and thus Kraig Labs has exclusive global commercialization rights with the technologies developed, including methods, organisms, and fibers produced.
MANAGEMENT
Kim Thompson, Founder and CEO
As the CEO of the company, Mr. Thompson is the only member of the scientific advisory board who is also
a part of the corporation's management. His formal education lies in the fields of economics and law.
He received his B.A. in Applied Economics from James Madison College at Michigan State University.
He received his Juris Doctorate from the University of Michigan Law School in 1994.
Mr. Thompson founded Kraig Biocraft Laboratories in his pursuit of the development of new biotechnologies
with industrial applications. As chairman of the scientific advisory board, he brings a unique perspective,and
acts as the primary liaison between the advisory board and the corporation.
Mr. Thompson brings a wealth of experience in business management and consultation to Kraig. Following
the completion of his undergraduate degree, Mr. Thompson joined California Craftsman, Inc. as a
Vice-President with primary responsibility for both marketing and human resources.
Kim Thompson was the director of business development at Franchise Venture Partners, LLC. He subsequently
joined the firm of Shearson, Lehman, Hutton where he specialized in equity trading and research of small cap
companies. Mr. Thompson received the highest series seven score for all Shearson brokers in his class nationwide.
His experience in those small cap equity markets has proven to be invaluable both in his legal and business successes.
Prior to becoming a public company CEO, Mr. Thompson was the founder and senior litigation partner in a California
commercial law firm where he worked as corporate and litigation counsel to privately held and public companies.
His many accomplishments in corporate law include winning and collecting in full what his firm believes to have been
the largest award of lost profits in a California commercial arbitration up to that time. An important part of his work was
winning victories on behalf of corporate clients in disputes over intellectual property and distribution rights. He has
represented business clients ranging from small start ups and micro caps to Fortune 100 companies.
With a background in business leadership and in advising public and private corporations, Kim Thompson continues
to bring a unique perspective to the successful management of business. His extensive business and legal background
enables him to create practical solutions to business problems and seize opportunities for growth.
Mr. Thompson is a member of the Triple Nine Society for persons with documented genius level IQs (having tested above
the 99.9th percentile). He is also active in the realm of science and invention where he has to his credit a number of
provisional patent applications including innovations in the areas of biotechnology, organic polymers, genetic engineering
and magnetic field manipulation, among others.
Mr. Rice has over 13 years’ experience growing development stage businesses with a focus on technology development, commercialization, and go to market strategies. Mr. Rice holds a B.S. in Chemical engineering from Michigan Technological University.
Prior to joining Kraig Biocraft Laboratories Mr. Rice was the Director of Advanced Technologies for Ultra Electronics, AMI. In this role, Mr. Rice was responsible for the identification, capture, and execution of new technology programs. During his tenure with AMI, Rice secured more than twenty five million dollars in funded development programs from the US Department of Defense which his team successfully leveraged into commercially viable spinoff products. Mr. Rice was also responsible for technical sales, marketing, and promotion of AMI’s products and capabilities. Rice joined AMI as the third full time employee and helped to lead the organization through its rapid growth and ultimate acquisition by Ultra Electronics in 2011.
Earlier in his career Mr. Rice developed unique advanced manufacturing techniques, established and trained a production staff, led engineering development, authored numerous technical papers, and is a recognized subject matter expert. Mr. Rice holds 5 issued patents and numerous provisional patents.
Mr. Rice brings a history of transforming revolutionary ideas into viable commercial products.
Mr. Rice is currently completing his Masters of Business Administration through the Executive Program at the Eli Broad College of Business: Michigan State University.
Despite the huge potential of genetically modified animals outside of laboratory research, commercialisation of these animals has been extremely limited. Numerous factors, including negative consumer perception, regulatory hurdles, and limitations inherent to classical GM technologies, have kept the majority of GM animal applications within the realm of academic research. However genome editing using zinc finger nucleases could help develop new markets for the future commercialisation of GM animals.
Genetic modification is commonplace throughout the life sciences sector, from fundamental research to pharmaceutical testing. GM cellular and animal models are valuable tools for the study of many chronic diseases, the testing of pharmaceutical compounds and the development of new therapeutic strategies. Genetic modification also offers great benefits in vaccine and biopharmaceutical manufacturing, which rely heavily on the use of GM organisms for biomolecule design and production. Modifying the genome of an organism or cell line allows the incorporation of target biomolecules in specific biological contexts, as well as the transfer of a gene product from a low-producing organism to one that can produce on a commercial scale. These applications have been widely accepted for many years, with countless GM organisms approved for medical manufacturing applications by drug regulators in all major countries. Despite this widespread success within the research and pharmaceutical sectors, the use of GM organisms outside of these markets has been limited.
Despite the lack of broad acceptance for most commercial applications of GM animal products, this technology has been able to gain traction in a few market sectors. The most obvious application has been the commercialisation of transgenic animals for the production of biomolecules for therapeutic use. Cattle, sheep and goats have been used for large-scale production of antibodies, steroids and hormones - most notably insulin - for many years. In 2009, GTC Biotherapeutics received US FDA approval for bioproduction of a recombinant human antithrombin. This product - ATryn - is extracted from the milk of transgenic goats, and is the first approved biopharmaceutical to be produced using genetically engineered animals. Although this is a significant breakthrough for the commercialisation of GM animals, it is still within the pharmaceutical industry, and is a natural progression of existing cell-based technologies. Of potentially greater commercial interest is the extension of genetic engineering outside of this sector, into areas such as food production, textiles and even companion animals.
GM crops have been available in many countries since the early 1990s, and numerous cash crops - including sugar beet, soybean, corn and tomatoes - have been modified to improve resistance to disease, increase the rate of growth or enhance nutritional value. However, cultivation of these transgenic crops is generally tightly regulated, particularly within the European Union, and this, together with negative public opinion, has limited the more widespread development of GM technologies.
Similar to GM crops, many of the animals currently under development are intended to confer disease resistance, an application particularly suited to the use of zinc finger nuclease (ZFN) technology. Many diseases can be treated by the targeted deletion or modification of a host gene. With ZFNs, these targets can be modified with no footprint of genetic engineering. Due to the high costs of raising livestock, another area of focus in developing commercial GM animals has been increasing the rate of growth or size of animals. Among the first GM animals likely to be launched is a fast growing salmon from AquaBounty. The AquAdvantage Salmon is designed to reach market size in half the time of a wild type salmon, reducing costs for fish farmers and limiting the environmental impact of salmon farming by avoiding the need for ocean pens.
Although genetic engineering of animals for food is primarily driven by economic pressures, GM technologies have also been used in the companion animals market. In this sector, genetic modification can be used for practical purposes - such as the creation of hypoallergenic animals or the correction of heritable congenital defects which have arisen though inbreeding - or for purely cosmetic purposes, such as GloFish. The first example of a GM pet, GloFish are fluorescent zebrafish (Danio rerio) that have had genes encoding naturally fluorescent proteins (GFP, YFP, RFP) inserted into their genome. Developed by a group at the National University of Singapore, GloFish were originally created to develop live detection systems for water pollution. They were introduced as pets in the United States in 2003 following over two years of extensive environmental research and consultation. In Europe however, the sale and possession of GloFish is prohibited by rigorous legislation concerning the use of GM technologies.
By allowing precisely targeted insertion of spider genes and concomitant removal of endogenous silkworm silk genes at the same locus, ZFN technology offers the potential for development of transgenic silkworms which will produce native spider silk at commercially viable levels
Perhaps even more interesting from a commercial perspective is the use of GM animals in the manufacture of textiles. Silkworms - actually the larval form of the silkmoth Bombyx mori - have been used for the production of silk for thousands of years, with natural silk still produced by the cultivation of silkworms today. Silkworm cocoons are unwound to create linear silk threads, then re-spun into textiles in much the same way as cotton. Although the applications of silkworm silk are numerous, due to their unique physical and chemical properties, there is also widespread interest in the silks of several other insects.
Spider silk, in particular, offers numerous possibilities within the technical textiles industry, due to its incredible tensile strength and elasticity; characteristics which have not yet been replicated in synthetic materials. Like all insect silks, spider silk fibres consist of repetitive units of protein crystals separated by less structured protein chains. The exact properties and composition of each spider silk vary with its intended function. Major Ampullate or dragline silk, for example, is relatively hydrophobic with very high tensile strength and toughness, as it is used to form the outer rim and spokes of a web. In contrast, hydrophilic capture spiral silks, which form the inner structures of the web, are sticky and highly elastic to effectively entrap prey. This high degree of variability offers enormous potential for the textiles industry, raising the possibility of tailoring the properties of silk to create advanced technical fabrics, for applications such as bulletproof vests, parachute canopies and automobile airbags; biomedical applications, including sutures and tendon and ligament repair; new fabrics, for sportswear and clothing; and even microelectronics.
Although the use of spider silks for microsutures has recently been reported, more widespread application of spider silk technologies is currently limited by the difficulty in producing silks on a commercially viable scale. This is due to the difficulties of rearing spiders in large numbers, due to their highly territorial and cannibalistic nature. As a result, the harvesting of spider silk fibres is extremely time consuming and labour intensive, with production of the only known spider silk garment - an 11 foot by 4 foot shawl made from golden orb spider silk - taking 150 people over five years to produce and costing in excess of £300,000!
.
To overcome these limitations, and allow future development of spider silk technologies, an alternative strategy for spider silk production is required. This makes spider silk production an obvious candidate for genetic modification, inserting spider silk genes into the genome
of other silk-making insects for bioproduction. For example, random insertion of orb spider silk genes into silkworms has allowed production of hybrid spider/silkworm silk using traditional silkworm farming strategies. The resulting hybrid silk contains approximately 10% spider silk
and has greater strength and durability than native silkworm silk, raising the possibility of using transgenic silkworms to produce pure spider silks.
Though straightforward in principle, the exchange of native silkworm genes for spider silk genes, alongside more widespread exploitation of genetic engineering, has been limited by the inherent restrictions of conventional GM technologies.
The generalised process of modifying an organism requires several capabilities, including:
While many different techniques exist for accomplishing each of these steps, most GM technologies offer a compromise between the efficiency of the technique and the ability to accurately and precisely target the locus of interest. Viral genomic delivery technologies effectively deliver nucleic acids to cells and organisms, but fall short on ability to target specific regions of the genome, generally only allowing random insertion of genetic material. In comparison, transposase technologies allow a greater degree of targeting, but leave unwanted traces of exogenous DNA in their wake. Other methods involve the introduction of naked DNA into the cell, which results in insertion into the genome at very low frequencies, usually at random, limiting this approach to organisms that can be economically cultivated at high densities and screened in large numbers. Simply put, most techniques for genetic manipulation are random, inefficient and leave a 'footprint' of foreign DNA. While this is usually tolerated in basic research, it is not acceptable for most commercial applications, and has been a major hurdle for GM animal technologies to date.
The advent of zinc finger nuclease (ZFN) technology represents a significant breakthrough for commercialisation of GM animal products, offering precisely targeted, efficient genome editing for the first time. Commercially available through Sigma Life Science under the CompoZr brand, this technique can be used to create permanent and heritable changes to an organism of interest.
This high degree of variability offers enormous potential for the textiles industry, raising the possibility of tailoring the properties of silk to create advanced technical fabrics
ZFNs are a class of engineered DNA binding proteins that facilitate targeted editing of the genome by creating double-strand breaks at user-specified locations. These breaks stimulate the cell's natural DNA repair mechanisms - homologous recombination (HR) and non-homologous end joining (NHEJ) - which can be exploited to achieve rapid and permanent site-specific modification of the desired genes. While HR can be used to insert foreign DNA sequences, NHEJ allows the cell's natural processes to create precisely targeted mimics of natural mutations which leave no traces of foreign DNA. Unlike previous techniques, ZFNs offer excellent sequence specificity, binding 24 to 36 base pair target sequences to virtually eliminate off target effects, and are able to achieve modification rates exceeding 20 %, well above rates for most other technologies.
The technique is already being used to create transgenic silkworms for spider silk production. By allowing precisely targeted insertion of spider genes and concomitant removal of endogenous silkworm silk genes at the same locus, ZFN technology offers the potential for development of transgenic silkworms which will produce native spider silk at commercially viable levels.
GM technologies have revolutionised the research world and have great potential in a variety of commercial applications, but have been limited by the inherent restrictions associated with historical GM technologies. The main drawback of these technologies is their inability to accurately and efficiently target genes of interest, instead relying on random insertion of genetic material into host genomes. These limitations result in the need for extensive and costly screening to identify animals with correct transgene expression (without compromising the viability of the animal), and also result in the co-expression of both the transgene and native homologues already present.
The advent of ZFN technology signifies the beginning of an exciting new chapter in the world of genetic modification, allowing precise, targeted and efficient genome editing for the first time. Production of native spider silk using transgenic silkworms is just one example of the potential commercial applications of this innovative technology, taking us one step closer to the reality of industrial scale biomanufacturing and paving the way for an entirely new spectrum of environmentally friendly materials.
Authors:
Joseph Bedell and Brian Buntaine
Commercial Animal Technologies Group, Sigma Advanced Genetic Engineering (SAGE) Labs, Sigma Life Science
HEADLINES FOR KRAIG BIOCRAFT LABORATORIES / (KBLB):
PHOTOS FROM VIETNAM POSTED JULY 6, 2018
ANN ARBOR, Mich., – January 7, 2019 –Kraig Biocraft Laboratories, Inc. (OTCQB: KBLB) (“Company”), the leading developer of spider silk based fibers, announces today that it has successfully delivered the first two shipments of its highly specialized silkworms, which produce a silk with the physical characteristics of spider silk, to Vietnam.
Today’s announcement is the culmination of more than 5 years of work, and challenging negotiation, with the government of Vietnam. The silkworms from these first two shipments have already hatched and are now enjoying a fresh mulberry diet, so, for the first time in history, the global demand for spider silk materials has a viable, cost effective, and scalable solution.
“The dream of commercializing our powerful technology is now materializing. This marks a dramatic leap forward in Kraig Labs’ business plan for commercial production and mass marketing of cost effective recombinant spider silk, and becomes the foundation for an entirely new industry,” said, COO, Jon Rice. “To our long-term shareholders, who have taken this journey with us, as well as our team in the US and Vietnam, who have worked tirelessly to make this dream a reality, I cannot thank you enough. As we start the New Year, full of new opportunity, we truly have something incredible to celebrate.”
The Company has been working with leading sericulture experts, biotechnology institutions, and governmental agencies, in Vietnam, to further boost the silk industry with our revolutionary technology. Kraig Labs is currently finalizing renovation plans for a ~46,000 square foot production factory in Quang Nam Province, Vietnam.
“Our plan has always been to bring our technology to the silk producing regions of the world for rapid scale-up,” said, CEO and Founder, Kim Thompson. “Today we see the fruits of that effort. With its massive silk infrastructure and production capacity, Vietnam is an ideal location to launch our technology scale-up. Congratulations to our team and shareholders, as we prepare for the realization of large scale production.”
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