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Last Post: 6/27/2017 10:26:57 AM - Followers: 90 - Board type: Free - Posts Today: 2


Non-Muscle invasive Bladder Cancer ("NMIBC")

Heat Biologics has developed an ImPACT-based treatment for patients with NMIBC.  Similar to HS-110, HS-410 was designed based on knowledge of the various antigens that are known to be shared amongst a high proportion of patients with bladder cancer. Heat is currently conducting a Phase 2 trial using HS-410 for the treatment of NMIBC. This trial is being performed either in combination with the standard of care, BCG therapy, or alone. Heat believes that BCG is likely to synergize with HS-410 due to the activity of BCG to promote trafficking of HS-410 activated cytotoxic T cells into the bladder endothelium. On the other hand, monotherapy HS-410 has significant patient administration advantages by avoiding intravesical delivery, thus evaluation of its single-agent activity is warranted.

For more information please reference study protocol NCT02010203 on

About Non-Muscle Invasive Bladder Cancer

In 2015, the American Cancer Society estimated 74,000 new cases of bladder cancer will be diagnosed in the U.S. and an estimated 16,000 deaths will occur. More than 500,000 people in the U.S. have been treated for bladder cancer and 70% of those patients have non-muscle invasive bladder cancer.  Importantly, the U.S. Food and Drug Administration has not approved any new drugs to treat bladder cancer in more than 25 years. Heat's HS-410 represents a viable opportunity to address a significant unmet medical need.


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HTBX News: Confidential Treatment Order (ct Order) 06/14/2017 03:49:26 PM
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#2206   Bonou2 I could not agree more with what Spike5 06/27/17 10:26:57 AM
#2205   Here it is hard to say how it Bonou2 06/27/17 07:24:47 AM
#2204   Who do you think ? The idiots running Spike5 06/26/17 01:11:46 PM
#2203   Who is they Rogerthat1 06/26/17 12:45:40 PM
#2202   They should get an award for the way Spike5 06/26/17 11:52:00 AM
#2201   Companies that can't do, print paper to try Full Contact Yoga 06/25/17 12:17:42 PM
#2200   I never understand R/S it always kills the stock Spike5 06/24/17 12:33:00 PM
#2199   I know it will just wishful thinking .. Spike5 06/23/17 02:36:58 PM
#2198   It likely will, very rarely are they blocked. Full Contact Yoga 06/23/17 12:54:44 PM
#2197   I hope this R/s does not go thru Spike5 06/21/17 09:27:59 PM
#2196   The manipulation of this stock is masterful Spike5 06/21/17 12:52:26 PM
#2195   Wish I could disagree with you yoga but Spike5 06/21/17 11:50:55 AM
#2194   It's a failing entity a week away from Full Contact Yoga 06/21/17 11:35:29 AM
#2193   This is the only pig down on a Ruffieruff 06/21/17 10:52:51 AM
#2192   Now I know what being buried alive feels Spike5 06/20/17 04:13:17 PM
#2191   R/S is never good it will sink this Spike5 06/20/17 10:42:25 AM
#2190   Seems that way. POS. R/S coming Ruffieruff 06/20/17 10:26:09 AM
#2189   Oh well let's face it we all bought Spike5 06/20/17 10:14:46 AM
#2188   Checkpoint inhibitor companies need help! Safety is a dia76ca 06/19/17 11:17:38 AM
#2187   What could this be? itsabouttime 06/19/17 08:05:44 AM
#2186   They really need to avoid that R/S ... Spike5 06/16/17 04:04:45 PM
#2185   It's a turd...maybe after RS. Full Contact Yoga 06/16/17 03:54:20 PM
#2184   Down again .... wow I hate being right Spike5 06/15/17 04:46:15 PM
#2183   Thanks for information itsabouttime 06/15/17 09:06:40 AM
#2182   Someone posted that todays Confidentiality Treatment Order pertains dia76ca 06/14/17 06:47:38 PM
#2181   The pipeline page has also been changed...mentions HS-120...and dia76ca 06/14/17 03:52:14 PM
#2180   Same crap regurgitated as the stock price continues Spike5 06/14/17 01:06:20 PM
#2179   As well as improving the May 30 company dia76ca 06/14/17 12:40:52 PM
#2178   Near the end of the article it speaks dia76ca 06/14/17 11:53:36 AM
#2177   Interesting overview of Immunotherapies... dia76ca 06/14/17 11:49:49 AM
#2176   Total manipulation Spike5 06/14/17 10:49:05 AM
#2175   It is hard to know about timing. They dia76ca 06/14/17 10:28:29 AM
#2174   They should have to complete grant paperwork annually, Full Contact Yoga 06/14/17 09:45:30 AM
#2173   Curious to know the possible timeline for a itsabouttime 06/14/17 08:47:24 AM
#2172   HS-110 (viagenpumatucel-L) – Non-Small Cell Lung Cancer itsabouttime 06/14/17 08:35:20 AM
#2171   If this stock continues on the path it Spike5 06/13/17 01:24:38 PM
#2170   Curious to know the possible timeline for a itsabouttime 06/13/17 09:01:09 AM
#2169   no plans on attending will be outside US itsabouttime 06/13/17 08:36:05 AM
#2168   Some body is sure lapping this thing up oltimer 06/12/17 04:06:40 PM
#2167   Yep. Might be a good trade post Full Contact Yoga 06/12/17 12:26:38 PM
#2166   About Heat Biologics, Inc.(Good summary) dia76ca 06/12/17 11:16:37 AM
#2165   Two presentations coming up...any one attending from this board? dia76ca 06/12/17 11:09:36 AM
#2164   Into the 50's by week end ... very Spike5 06/12/17 10:40:44 AM
#2163   Yoga I'm afraid this one is heading into Spike5 06/12/17 10:38:02 AM
#2162   They have the "yes" votes already, no need Full Contact Yoga 06/10/17 12:46:24 PM
#2161   Here is more information on that trial. dia76ca 06/10/17 11:01:11 AM
#2160   Think I found my answer on the trials itsabouttime 06/09/17 07:55:14 PM
#2159   Hey yoga I voted no to the split Spike5 06/09/17 04:29:07 PM
#2158   RS is never good. Dump before, it will Full Contact Yoga 06/09/17 01:05:30 PM
#2157   dia76 Some body is acc this thing big time oltimer 06/09/17 12:51:51 PM