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genisi

04/25/11 5:24 PM

#118837 RE: zipjet #116804

JCV immunoassay

But I wonder if the truth is more complex. Patients are only being told they are positive or negative. Is that really all the test does? Is there no measure of viral titer? Or is that being done and not being released? Or is this being done to establish some baseline counting on better tests later?


It is an enzyme-linked immunosorbent assay (ELISA) that can find detectable or not detectable levels of anti-JCV antibodies in the plasma. Biogen is looking for genetic variation in the host and virus that could be linked to higher susceptibility to develop PML. I don't expect much from this study.