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Bruinfan4ever

12/12/17 4:10 PM

#207809 RE: BabyBioBull #207806

Very nice post. Thanks.
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TheDane

12/12/17 4:27 PM

#207811 RE: BabyBioBull #207806

Excellent post!
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DaubersUP

12/12/17 4:33 PM

#207813 RE: BabyBioBull #207806

Thanks. I have a better understanding with an example like that.
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cabel

12/12/17 4:38 PM

#207815 RE: BabyBioBull #207806

Great easy to understand post!!
Thanks for that!!
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Jhawker

12/12/17 4:41 PM

#207817 RE: BabyBioBull #207806

Also when you factor in reduced duration and or severity which we will know shortly it is very compelling!
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BooDog

12/12/17 5:35 PM

#207832 RE: BabyBioBull #207806

Awesome way of breaking it down. Excellent!
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CallMeCrazy

12/12/17 5:44 PM

#207834 RE: BabyBioBull #207806

Very, very well put. eom
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DesireToLearn

12/12/17 6:36 PM

#207850 RE: BabyBioBull #207806

Not to mention a potential better delivery method besides swish and spit.
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LilyGDog

12/12/17 8:06 PM

#207861 RE: BabyBioBull #207806

MoCTIX,

Great post!!

Go Leo & IPIX!

Example using IPIX B-OM phase2 percentages. Let’s use the low and more conservative 60% for placebo vs the more realistic 75% number seen in previous trials. So if there were 1000 patients being treated with Throat and Neck cancer at least 600 would get OM without any treatment to PREVENT getting OM. If those same 1000 patients did a simple swish and spit 3 times a day with B there would be 368 people that still would get OM meaning 232 of the 600 would NOT GET the OM disease by using B. (Per protocol population of 36.8% so 368 people vs 600 people). Reducing the odds of getting OM by 38.66% (232/600). So using the conservative 60 placebo number B will reduce the chances of GETTING OM by 38.66%. Using a more realistic number of 75% instance of getting OM that number goes from 38.66% to 50.93% PREVENTION rate. If you could reduce your chances of getting a disease that makes it extremely difficult to eat, drink or swallow by 39-51% by doing a simple swish and spit would you do it? If you were a doctor that cared for your patient’s well-being would you subscribe it? BTW, there were ZERO instances of SAE related to B (extremely safe to use). As others have mentioned we haven’t even seen secondary data to see improvements of symptoms using B which is gravy on top of meeting the study’s primary endpoint. I am a retired computer sales guy with zero medical background. Do you think the medical and business people in big pharma with full access to all the data under NDA will figure this out? My money says they will/have.

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rmzport

12/12/17 9:09 PM

#207875 RE: BabyBioBull #207806

I'm betting when final data is revealed that 100% of the B users will show some level of clinical benefit just as we saw in the B-UP trial.