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Titan V

10/11/17 10:54 PM

#214223 RE: biomaven0 #214215

Thanks for the reply Peter. I agree that they should look to partner out VK5211 if p2 data looks promising this quarter. The drug has gone through a few generations of improvements over a decade. It might have a decent shot at producing some good results. As for their NASH pipeline, some folks think it should be valued the same as MDGL. So your bet might be worth it in 1H18. Nevertheless, I too am treating it like a lotto stock with a small position only.

Speaking of Ligand, I think of Captisol, and then another one of my lotto picks which has done really well in the last two months - MRNS. They have phase 2 PPD data due this quarter, and in this trial they are using Captisol-enabled Ganaxolone. Sage used Captisol with their phase 2 PPD compound that did really well. Does that mean Ganaxolone will also meet p2 endpoints, also given they are identical compounds with the same MOA? Can't say for sure but I like the odds here of some further gains. Regards.



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Titan V

10/21/17 12:44 PM

#214481 RE: biomaven0 #214215

Risk of Death Persists for Years after Hip Fracture
https://www.medscape.com/viewarticle/729944

I think VK5211 has to potential to become a blockbuster drug someday (300,000 hip fracture cases annually in the U.S. alone). Pro-athletes and bodybuilders already using SARMs off label with success. Looking forward to phase 2 data this quarter. VKTX is up 200% in the last two months but is still way below it's IPO price of $10.

Viking Therapeutics: What Direction Now For This ~$2.50 Biotech 'Busted IPO'?
https://seekingalpha.com/article/4114591-viking-therapeutics-direction-now-2_50-biotech-busted-ipo

Viking Therapeutics: Welcome To The Glorious House Of Gains
https://seekingalpha.com/instablog/42897536-bumbershoot-holdings/4577896-viking-therapeutics-welcome-glorious-house-gains
(I would ignore the tone of the article.)