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02/18/16 8:10 PM

#54377 RE: koman #54368

koman,

I was hoping someone else could confirm my recollection about early psPD vs. late but if not I'll do some digging through my notes to see where I recall that from. As to the later psPDs being misclassified and placed into the main trial, I think a determination was made to aim treatment at those who fell into an expected range of PFS and OS to increase confidence level by reducing variance. Classification being less important for SOC vs. treatment than expected PFS or OS. Hope this makes sense.