"There were statistically better results..."???
Well, first, at ONE week post therapy, the results were NOT significantly better. In some "magical" fashion, the results BECAME significant at THREE weeks, however.
More important, however, is that NOWHERE is there ANY indication as to whether patients were restricted from changing their analgesic intake OR from engaging in alternative therapies such as, say, a laying down with a heating pad. It also doesn't indicate whether the subjects resumed their normal daily activities.
Now, say the calmare actually made patients WORSE -- SOME calmare patients have claimed that, you do realize? Suppose then, in consequence, those patients DOUBLED their intake of analgesics or engaged in alternate therapies and -- in consequence -- felt a whole LOT better!
THEN the studies alleged "significant" results become TOTALLY BOGUS since it wasn't the calmare making the symptoms better, but the OTHER treatments!
DITTO for the "pain mRNA" results!