Amarin Corp Plc (AMRN)

[Hspooner]

Omega-3-acid Ethyl Esters (Lovaza) For Severe Hypertriglyceridemia


Renee R. Koski, PharmD, CACP

"In these studies, Lovaza decreased TG levels by 26% to 47%, whereas corn oil placebo increased them by an average of 6.7%. The higher the baseline TG level before therapy began, the greater the percentage reduction achieved after therapeutic drug levels were attained.

These trials also demonstrated a 10% to 46% increase in LDL-C levels and an increase of 11% to 14% in HDL-C levels with the active drug versus a 4.8% decrease in LDL-C levels and no change in HDL-C concentrations with placebo."