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DonShimoda

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DonShimoda

Re: jq1234 post# 154204

Saturday, 12/15/2012 11:19:36 PM

Saturday, December 15, 2012 11:19:36 PM

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Were you aware of these cases before FDA label?

Yes, I was aware of the hepatotoxicity issue before yesterday. I believe this issue was discussed during the initial presentation of the PACE data at last years ASH meeting. If I'm not mistaken, all 3 deaths occurred in blast phase patients. Clearly, this isn't going to be an issue in a 1/2 line setting. As far as I'm concerned, it will have little impact on the long-term commercial success of the drug.

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