If we do not get a halt due to overwhelming efficacy, standard language for DMC's is to simply state the recommendation for continuing to final. In other words, we may not get ANY other info. Net, this is still positive, but may cause a temporary letdown in the stock. (more news should follow, i.e. Dignity and CRLM trials, and the ever-possible license agreement, plus product #4, etc... so the stock would remain quite volatile)
Based on the language change from "reach 190" to "confirm 190" I am operating under the assumption that we hit it a while ago. The issue? Events involving tumors need a radiologic review that could take from 1 to FOUR freaking months to confirm. I suspect they will not dally around with these, but they are not on the investors' timetable, unfortunately. Guidance was for 600 and 190 to occur "around the same time" so I really do feel comfortable saying they have already hit, probably back in early-to-mid August. In that case? Say 1-2 months for review and the ol' 6-8 weeks for the interim calc. That'd be around November 11. (I really hope its earlier!!!)
Then - we also have to think that if they do take a while to confirm the last couple events, by the time they have done so, there may well be around 200 events that are all confirmed. So - the interim calc might be performed with MORE THAN the 190 events.
Regards,
Trond
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