Anavex Life Sciences Corp (AVXL)

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Stories and Accounts Will Be Shared

Those topline 371 results for Schizo could destroy many shorts even before 273 approval finishes the job.

If Anavex 3-71 effectively treats schizophrenia, how might both patients and caregivers actually know? Specifically, what are schizo’s symptoms, the things that would be obviated by the Anavex drug. Here’s a list of them:

Delusions. This is when people believe in things that aren't real or true. For example, people with schizophrenia could think that they're being harmed or harassed when they aren't. They could think that they're the target for certain gestures or comments when they aren't. They may think they're very famous or have great ability when that's not the case. Or they could feel that a major disaster is about to occur when that's not true. Most people with schizophrenia have delusions.

Hallucinations. These usually involve seeing or hearing things that other people don't observe. For people with schizophrenia, these things seem real. Hallucinations can occur with any of the senses, but hearing voices is most common.

Disorganized speech and thinking. Disorganized speech causes disorganized thinking. It can be hard for people with schizophrenia to talk with other people. The answers people with schizophrenia give to questions may not be related to what's being asked. Or questions may not be answered fully. Rarely, speech may include putting together unrelated words in a way that can't be understood. Sometimes this is called word salad.

Extremely disorganized or unusual motor behavior. This may show in several ways, from childlike silliness to being agitated for no reason. Behavior isn't focused on a goal, so it's hard to do tasks. People with schizophrenia may not want to follow instructions. They may move in ways that are not typical or not appropriate to the social setting. Or they may not move much or respond at all.

Negative symptoms. People with schizophrenia may not be able to function in the way they could before their illness started. For example, they may not bathe, make eye contact or show emotions. They may speak in a monotone voice and not be able to feel pleasure. Also, they may lose interest in everyday activities, socially withdraw and have a hard time planning ahead.

https://www.mayoclinic.org/diseases-conditions/schizophrenia/symptoms-causes/syc-20354443

Two important considerations.

First, how subtle might Anavex 3-71's results be? Easy for anyone to see; or slight and questionable?

Secondly, how long might it take for Anavex 3-71 work: days, weeks, or months?

Simply, results will be clearly visible to all; patients and others. The list of symptoms will simply be gone or so reduced that everyone will instantly be happy.

I find no indications, in murine (lab-animal) tests, that Anavex 3-71's mechanisms of action (MOAs) will require lengthy periods to be effective. Results should appear promptly.

Let’s see if the clinical results fit these perspectives. If so, the massive population of schizophrenia patients will be enthused. The stories should proliferate, resulting in prompt FDA approval.