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Re: plexrec post# 400109

Thursday, 01/26/2023 4:58:05 PM

Thursday, January 26, 2023 4:58:05 PM

Post# of 457588
What counts more, real behaviors, or statistical datapoints?

--did say witnesses have seen changes in folks who have taken the drug--definite RWE [real world evidence] being seen--can tell who has been on placebo or has taken the drug--


Thanks for posting this. Exactly what I would have expected to be noted and said by Anavex insiders; people who know what actually happened in the Alzheimer's clinical trial.

Who might have been the observers of these definitive behavioral improvements in the clinical study patients taking blarcamesine? Could they have been wrong?

First, of course, no one, neither patients themselves nor anyone else, could have known who was actually taking the drug, as opposed to the visually identical placebo. It was a properly-blinded study.

But seeing, even recording patient behaviors during the study would have been for the most part, nurses and medical technicians. Perhaps a few observations were made by physicians. But in any case, it appears (well, did appear) that the behaviors of the experimental group, those taking blarcamesine, were decidedly separate and better than those in the placebo group. Tell us, how could the observers have gotten it wrong; that one group of trial participants exhibited easily discerned behavioral or cognition improvements? Simply, if blarcamesine didn't work, no one would have been able see any differences among the trial participants. Everyone would exhibit typical Alzheimer's cognition debilities. But, nope, one set of patients behaved differently, got better.

Plain and simple. In treating Alzheimer's, blarcamesine actually works (and safely, without any brain bleeding).
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