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DewDiligence

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Re: JK2016 post# 2197

Tuesday, 04/19/2022 9:46:01 AM

Tuesday, April 19, 2022 9:46:01 AM

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Ascletis’ ASC11 could be a serious competitor to EDP-235 based on the in vitro assays of potency described in the PR (https://finance.yahoo.com/news/ascletis-announces-3clpro-inhibitor-asc11-085000053.html ). However, the most consequential differentiators among agents from this drug class are safety and pharmacokinetics, and Ascletis’ PR is silent on these points. We’ll have to wait for Ascletis’ phase-1 data in late 2022 (or early 2023) to know how their drug actually stacks up.

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