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Re: KMBJN post# 367337

Tuesday, 07/27/2021 5:54:10 PM

Tuesday, July 27, 2021 5:54:10 PM

Post# of 402566
"It's good (and fun) to discuss the science. Thanks for engaging and posting about the MOA(s) of brilacidin."


Although literally no one wanted to address this question of mine, and I think it's an interesting question still:

""In this regard, compounds such as EIDD-280, an oral antiviral targeting the catalytic site of nsp12 and
currently in phase II-III clinical trials against COVID-19,11
represent promising drug candidates for current and future
coronavirus pandemic threat
s"

I think that's a typo and they actually meant EIDD-2801:

https://www.researchgate.net/publication/349172933_SARS-CoV-2_infection_is_effectively_treated_and_prevented_by_EIDD-2801

Doubtless one of the scientific mavens who follow IPIX so closely wil be able to tell us if defensin mimetics such as brilacidin can target nsp12 and nsp13."


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