Wayne, Pennsylvania, June 12, 2006 - Millstream II Acquisition Corporation (OTC Bulletin Board: MSMA) announced today that it has signed two separate letters of intent with companies for a business combination. The Company anticipates signing a definitive agreement with one of these companies within the next 45 days. Pursuant to the provisions of the Company’s Certificate of Incorporation, the Company now has until December 23, 2006 to complete a business combination. If the Company is unable to complete a business combination by December 23, 2006, it will then liquidate.