Home > Boards > US Listed > Biotechs > Adaptimunne Therapeutics (ADAP)

It is encouraging. I would like to see

Public Reply | Private Reply | Keep | Last ReadPost New MsgReplies (1) | Next 10 | Previous | Next
jondoeuk Member Profile
 
Followed By 17
Posts 1,257
Boards Moderated 1
Alias Born 10/24/15
160x600 placeholder
Current Report Filing (8-k) Edgar (US Regulatory) - 12/16/2020 5:01:45 PM
Current Report Filing (8-k) Edgar (US Regulatory) - 11/20/2020 7:37:37 AM
Adaptimmune to Showcase Market Potential for SPEAR T-cell Portfolio and Pipeline with Multiple Cell Therapy Platforms During ... GlobeNewswire Inc. - 11/20/2020 7:30:00 AM
Current Report Filing (8-k) Edgar (US Regulatory) - 11/19/2020 9:10:01 AM
Durable Responses with ADP-A2M4 in Synovial Sarcoma with Confirmed Responses in 44% of Patients and Disease Control Rate of 9... GlobeNewswire Inc. - 11/19/2020 9:00:00 AM
Adaptimmune to Host Virtual Investor Day on Friday, November 20th GlobeNewswire Inc. - 11/12/2020 8:00:00 AM
Two Confirmed Responses and Five out of Six Patients with Initial Tumor Reductions from Early Dose Cohorts of SURPASS Trial, ... GlobeNewswire Inc. - 11/9/2020 3:18:19 PM
Quarterly Report (10-q) Edgar (US Regulatory) - 11/5/2020 4:20:10 PM
Current Report Filing (8-k) Edgar (US Regulatory) - 11/5/2020 7:41:08 AM
Adaptimmune Reports Q3 Financial Results and Business Update GlobeNewswire Inc. - 11/5/2020 7:30:00 AM
Confidential Treatment Order (ct Order) Edgar (US Regulatory) - 11/4/2020 10:42:34 AM
Adaptimmune to Report Q3 Financial Results and Business Update on Thursday, November 5, 2020 GlobeNewswire Inc. - 10/22/2020 8:00:10 AM
Current Report Filing (8-k) Edgar (US Regulatory) - 10/15/2020 4:48:05 PM
Adaptimmune Provides Full Contents of its SITC Abstract for the Phase 1 SURPASS Trial GlobeNewswire Inc. - 10/15/2020 4:40:39 PM
Life-Saving Advancements, Treatments Delivered by Companies Invested in Innovation NetworkNewsWire - 10/2/2020 8:45:00 AM
Current Report Filing (8-k) Edgar (US Regulatory) - 8/28/2020 10:45:24 AM
Promising Data from Phase 1 Trial with ADP-A2AFP in Liver Cancer at the International Liver Congress Confirm Safety Profile a... GlobeNewswire Inc. - 8/28/2020 10:30:10 AM
Automatic Shelf Registration Statement of Securities of Well-known Seasoned Issuers (s-3asr) Edgar (US Regulatory) - 8/10/2020 5:02:42 PM
Quarterly Report (10-q) Edgar (US Regulatory) - 8/6/2020 11:17:57 AM
Current Report Filing (8-k) Edgar (US Regulatory) - 8/6/2020 7:38:25 AM
Adaptimmune Reports Q2 Financial Results and Business Update GlobeNewswire Inc. - 8/6/2020 7:30:10 AM
Adaptimmune Granted Access to PRIority MEdicines (PRIME) Regulatory Support by the European Medicines Agency for ADP-A2M4 for... GlobeNewswire Inc. - 7/23/2020 4:00:10 PM
Adaptimmune to Report Q2 Financial Results and Business Update on Thursday, August 6, 2020 GlobeNewswire Inc. - 7/22/2020 8:00:10 AM
Statement of Changes in Beneficial Ownership (4) Edgar (US Regulatory) - 7/1/2020 5:13:49 PM
Statement of Changes in Beneficial Ownership (4) Edgar (US Regulatory) - 7/1/2020 5:10:37 PM
jondoeuk   Thursday, 10/15/20 09:32:28 PM
Re: jondoeuk post# 108
Post # of 132 
It is encouraging. I would like to see some tumour shrinkage in the patients with SD.

Going forward, there are other ways to improve efficacy. This would include making changes to production (it seems they are in some cases), adding low-dose radiation (this is already being tested in another trial) [1], use of Ox/Cy over Flu/Cy (should improve trafficking to site(s) of disease and modulate the TME), and short-course decitabine (induces cancer-testis antigen expression) [2].

Refs:
1 https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(18)30449-0
2 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0139221

Public Reply | Private Reply | Keep | Last ReadPost New MsgReplies (1) | Next 10 | Previous | Next
Follow Board Follow Board Keyboard Shortcuts Report TOS Violation
X
Current Price
Change
Volume
Detailed Quote - Discussion Board
Intraday Chart
+/- to Watchlist
Consent Preferences