Globalist Reality Report

[DarthYoda]

"Immune Responses Regulated by Cannabidiol":
27 Feb 2020

IL-6 is a proinflammatory cytokine produced by many cell types, predominantly innate cells. Many studies have shown that circulating IL-6 is readily inhibited by CBD in inflammatory models, including diabetes, asthma, pancreatitis, and hepatitis. CBD treatment in vivo resulted in lower IL-6 production in peritoneal macrophages stimulated ex vivo with LPS, in the pancreas in acute pancreatitis, and in bronchoalveolar lavage fluid in LPS-induced pulmonary inflammation.

Using peritoneal macrophages from diabetic mice stimulated ex vivo with LPS revealed that macrophages isolated from CBD-treated mice did not produce as much TNF-a or IL-6 as macrophages isolated from vehicle-treated mice.

A direct effect of CBD decreasing macrophage numbers in the bronchoalveolar lavage fluid was shown following intranasal LPS administration to induce pulmonary inflammation.

https://www.liebertpub.com/doi/10.1089/can.2018.0073