Celsion Corporation (CLSN)

[Biobonic]

The Heat Trial had been recruiting

since 2008 here

It's my understanding that the HR separation becomes pronounced with more months into the study than the number of months in this Optima study's first look.


From the 3rd Q CC:

Number three, the rate of patient deaths for the OPTIMA study appears to be tracking well with the HEAT study perspective subgroup. As we suspected, however, overall survival from the OPTIMA study was not sufficiently mature to draw any conclusions. The study had a median follow up the OPTIMA study events. Had a median follow up of 25 months where's the comparative perspective subgroup had immediate follow up of 67 months. So I just give you a little suggestion here. If you'd like, graph for the prospective subgroup of 25 patients is published in the manuscript that's on our website. I encourage you to take a look, judge for yourself where a meaningful separation occurs.

Courtesy of SA, so the copy may be a bit garbled.