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Saturday, 10/20/2018 1:50:06 AM

Saturday, October 20, 2018 1:50:06 AM

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Welcome 2 The Jungle Of Another Potential Competitor

If breath and saliva are potentially out, what bodily fluid is left? U of T professor Andreas Mandelis from the Department of Mechanical and Industrial Engineering says that interstitial fluid is the answer.

Mandelis, whose lab is developing a non-invasive cannabis sensor, says interstitial fluid, the fluid surrounding all the cells in your body, carries an accurate ‘memory’ of substances that are in your blood. For THC, it only takes several minutes after it reaches your bloodstream for it to reach the interstitial fluid.

Mandelis and his team measure interstitial fluid THC levels using technology based on infrared radiation. To understand how this works, bear with me for a quick refresher on high school physics.

All materials and objects absorb and emit infrared radiation. This includes our own bodies: humans are constantly emitting infrared radiation, which, unlike light, is invisible to the naked eye. Instead, it is perceived as heat.

“It’s like in the movie Predator, where the predator couldn’t see in the visible light range but could see in the infrared range,” said Mandelis. “That’s why Arnold Schwarzenegger put mud on his face and body so that he would not be detected… It’s exactly those thermal photons we are looking at.”

What is not explained in Predator is that sometimes the wavelength in which a material — or even a molecule — emits radiation is distinct enough that it can be used to identify that material or molecule. “At that wavelength, at that peak, that only belongs to one molecule,” said Mandelis. This means that if the titular antagonist from Predator had a more sophisticated sensor, it could have identified Schwarzenegger as Schwarzenegger, not just as ‘human.’

Thankfully, Mandelis does have a more sophisticated sensor. In order to obtain that specific signature from THC, Mandelis’ sensor directs a laser at your fingertip. Once the laser penetrates to the interstitial fluid — just several microns below the surface of your skin — any THC molecules present will absorb the laser light and re-emit it as infrared radiation at a frequency that is specific to THC.

“Once the heat is emitted, I have an infrared sensor that can monitor that,” said Mandelis.

Here lies another benefit of testing interstitial fluid to monitor THC concentrations: it is non-invasive. In other words, you can measure the level of THC in your body without actually pricking, poking, or taking any sort of tissue or fluid sample.

https://thevarsity.ca/2018/10/14/weeding-out-the-high-drivers/

https://www.mie.utoronto.ca/mie/faculty/mandelis

Interstitial Fluid To Monitor THC Concentrations


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