Titan Pharmaceuticals Inc (TTNP)

[jsmith4]

This is quite a lengthy list of reasons to NOT prescribe Probuphine:

"Probuphine is unproven and not medically necessary for:1,3
? Patients who have not achieved and sustained prolonged clinical stability and tolerance to opioids for at least six
months.
? Patients who are maintained on sublingual or transmucosal buprenorphine at doses greater than 8 mg per day.
? Patients who are recently tapered to a lower dose of sublingual or transmucosal buprenorphine for the sole
purpose of transitioning to Probuphine.
? Patients who are new entrants to opioid dependence treatment.
? Patients who have already had one insertion in each arm.
? Patient who do not have viable sites for insertion in the upper arm.
? Patients who have an opioid-positive urine drug screen within the previous ninety days.
? Patient is currently being treated for chronic pain requiring opioids."