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Three Catalysts Early 2018

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finesand   Thursday, 03/01/18 10:46:15 PM
Re: finesand post# 1672
Post # of 1988 
Three Catalysts Early 2018

- 3/7 Lummy investment @ $4/sh (see prev post)
- AGS-003 ADAPT 290 events full readout
- AGS-004 Pilot Trial 12 patients full readout

Now we believe they postponed the good news a little bit on purpose, so nothing gets ruined by the RS in-between.

They lined up all ducks now one month post RS
and you may also add the general RS Dip recovery to the list of above material catalysts.

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AGS-003 ADAPT 290 events full readout

Quote:
The FDA agreed with the Company's plan to continue the trial in accordance with the current protocol to 290 events, the pre-specified number of events at which the analysis of overall survival, the primary endpoint, is to be conducted. The Company believes that 290 events will have occurred by late 2017 or early 2018. The Company also proposed to submit, and the FDA agreed to review, a protocol amendment to increase the pre-specified number of events for the primary analysis of overall survival beyond 290 events, which the Company believes could enhance its ability to detect whether Rocapuldencel-T has a delayed treatment effect. The Company can extend the study past 290 events without needing to enroll additional patients.



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AGS-004 Pilot Trial 12 patients full readout

Quote:

The favorable results of this study provide support for Argos' ongoing HIV eradication study in which AGS-004 is being administered in combination with vorinostat, a latency-reversing drug. This study is being conducted at the University of North Carolina, with planned enrollment of up to 12 patients and with initial data expected in early 2018. Funding for the development of AGS-004 for the treatment of HIV is being provided by the National Institutes of Health and the Collaboratory of Research for AIDS Eradication.



Clinical Trial NCT02707900

Quote:

Study Start Date : March 2016
Estimated Primary Completion Date : March 2018
Estimated Study Completion Date : December 2019



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