PharmaCyte Biotech Inc (PMCB)

[DragonBear]

But of course the ifosfamide is injected into the main pancreatic artery

Nope, of course not. The CIABs would be injected into a pancreatic artery near the tumor. Not the Ifosfamide.

and not in the arm as depicted generically on the ciab graphics

So Gunzburg made a mistake in the Table 1 graphics of his paper?

Someone should tell Kenny of this startling discovery. Because the last 10K Page 1 had that same generic syringe sticking in the arm.

It's fairly easy to drip a chemo drug into an arm vein over 1/2 hr. Although one must make sure the alkylating drug doesn't leak from the vein into the surrounding tissue. That causes a nasty necrosis of the surrounding tissue. Mind boggling would be the effort in dripping it into a catheter tube inserted into the groin, and leading up through a vein into the pancreas. Or will it be said that Gunzburg incorrectly stated in his paper:

Moreover, due to their flexibility and robustness, the cell-containing capsules (Figure 1A) can easily be injected through a needle or catheter without bursting, and they can specifically be delivered to the pancreas by the tumor vasculature under angiography...All of the patients in the first trial received ifosfamide at a dose of 1 mg/m2, whereas a dose of 2 mg/m2 was given in the second trial according to the label instructions, i.e., on Days 2, 3 and 4 and Days 23, 24 and 25 post capsule administration, plus an isodose of mesna to protect against urotoxicity

Please note Gunzburg never stated the Ifosfamide was injected via a catheter directly into the pancreas. Do you see any mention of its delivery via angiography? Where did this idea come from that Ifosfamide would be directly injected into the pancreas? Linky please.