Anavex Life Sciences Corp (AVXL)

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Compliance With Real Drugs Always A Problem

You received no benefit when the trial comes to an end.
There are no other viable options.
Are you really going to stop if the option to continue exists?

Sure, those demented people have continued to take their failed Alzheimer’s medication out of pure hope and anticipation (well, delusion). Nothing good happened during the trial proper, so they cleverly decided to continue to pop the pills each day for now, how long, how many, many months after the doctors and nurses were there overseeing Anavex 2-73 administration?

Talk to any nursing home nurse and ask about “compliance,” the tendency or ability of patients to take prescribed drugs exactly as prescribed, in the right dose, at the right time.

Prescription non-compliance is a major, frequently complicating factor in well-controlled, well-organized clinical trials of any drug. Assuring the highest patient compliance is a major item in clinical trial planning and conduct. FDA reviews compliance considerations with scrutiny. If non-compliance is allowed to occur, if trial patients fail or decide not to take the drugs exactly as prescribed, exactly when, how often, for prescribed periods, trial results are compromised, inaccurate, and invalid.

Prescription compliance is a problem with even the mentally sharp and competent. For a population of people of whom memory deficits are a prime debility, voluntary, unmonitored post-trial “compliance” is not at all probable for the entirety of those in Australia continuing for themselves, by themselves, to rigorously take Anavex 2-73 each day, especially if it had no really good therapeutic outcomes after dozens of months.

Substantiating evidence here:
https://en.wikipedia.org/wiki/Adherence_(medicine)