Vascular Biogenics Ltd (VBLT)

[mantoo123]

Agreed, combining with Avastin is/was the easiest and fastest path to approval. Indeed, many clinical trials struggle with finding patients ready to try an experimental drug. The Globe trial enrollment was finished ahead of schedule. I think this is mosltly due to combination with Avastin and less to word of mouth regarding VB-111 efficacy.

However, I still think it was a risky gamble as will be the ovarian p3 trial. This was stated almost verbatim by the CEO himself in one of his presentations in Hebrew. A bigger company with deeper pockets would have taken a different less risky route.

Anyway, if the gamble succeeds, then so much the better. However, if the gamble fails, it would be a waste of talent and years of development. The wait for the Globe trial feels like October 15th 1973 crossing of the Suez canal. It was the right move under the circumstances, but very risky as well. In hindsight, the crossing proved to be a tremendous success. I hope the Globe trial will be such a successful turning point for VBL.