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Wednesday, 07/05/2017 7:58:45 AM

Wednesday, July 05, 2017 7:58:45 AM

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NEWS OUT! MIDS Hybrid Strip Detection Testing to Commence

https://finance.yahoo.com/news/zenosense-inc-mids-hybrid-strip-113000726.html

VALENCIA, SPAIN--(Marketwired - Jul 5, 2017) - Zenosense, Inc. ( OTC PINK : ZENO ) ("Zenosense", the "Company"), a healthcare technology company primarily focused on the development and commercialization of MIDS Cardiac™, a Point of Care ("POC") handheld device for the early detection of certain cardiac event biomarkers to significantly accelerate the triage, diagnosis, treatment and disposition of patients reporting chest pain and with suspected acute myocardial infarction (heart attack), is pleased to announce that its MIDS Medical Limited joint venture ("MML") based at Sci-Tech, Daresbury (UK), has commenced testing of its "Hybrid Strip" system.

The Hybrid Strip is a first iteration simulation of the MML "MIDS" Lab-on-Chip ("LoC") test strip system, an assembled unit that replicates, as closely as possible, a fully integrated LoC system. The Hybrid Strip is designed to prove the principle of LoC nano-magnetic detection of high sensitivity assay sized quantities of paramagnetic nanoparticles. It will be used to gather data from low doses of nanoparticles & microbeads.

The Hybrid Strip consists of a micro machined, plasma coated plastic strip with a microfluidic channel designed to flow fluid entrained nanoparticles and microbeads into a magnetic entrapment and detection area. This was designed by MML in its laboratories at Sci-Tech, Daresbury in consultation with a European manufacturer highly experienced and specialized in biomedical microfluidics manufacturing. This process allowed MML to skip a planned step of flow simulation prior to production. Flow testing of the produced microfluidic strip suggests that its channel geometry will perform to design.

Hall Effect sensors are mounted on a flexible circuit board bonded to and integrated into the Hybrid Strip so as to locate the sensors in close proximity to the detection area. A number of these bonded and plasma coated strips have been produced in-house for the test program.

A 3D printed magnet holder assembly has also been designed and delivered to fit the Hybrid Strip. This will produce the precisely located bias magnetic field necessary to magnetize, move and entrap the nanoparticles within the Hybrid Strip.

Initially the proven master circuit board, previously used for testing the original "test slide" system, will be connected to test the Hybrid Strip. Testing is anticipated to commence this week and to continue over approximately six weeks.

Should the MIDS nano-magnetic detection system be proven to work in line with MML's expectations, the Company believes that the MIDS system will be applicable to POC high sensitivity troponin testing and a new generation of POC immunoassay tests, previously limited by optical detection methods.

Carlos Gil, CEO of Zenosense, Inc., commented: "I look forward to this commencement of testing of the Hybrid Strip. It is an exciting phase of our development, designed to definitively prove this remarkable, novel method of detection."