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Friday, June 23, 2017 10:07:49 PM
The JELIS secondary graphs are difficult to interpret because the Y axis is cumulative percent and the X measures time in years, but the number of enrollees changes (decreases) over time.. So to get the number of events over any given year you have to subtract the number of enrollees still in the 'at risk pool" remaining beginning the next year from those from the previous year...To get the rate you need to put the number events occurring during the year over the number of enrollees present at the beginning of the year...
Basically..the event rate varies year to year...due to scatter...there might be a slightly higher rate the first year,,,after that the event rate seems to be fairly constant..
This might be of some academic interest...but what we really want to know is how many are dying of CVD events and what the RRR is for the EPA arm...I do believe 30-35% RRR CVD mortality is in the cards...JELIS suggests EPA is most effective for serious events..So the question is do we total out 350 CVD deaths at 80% interim....If we do we should be home free.. Nothing close to a sure thing,,,but not impossible.
":>) JL
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