Saturday, February 27, 2016 7:45:20 PM
investingdog, I think that you are correct in the raw assessment that in SUNRISE Bavi seemed to fail.
However, in the more sophisticating assessment, that is including the COMPLETE information that PPHM has provided in the PR and Conference Call, what many poster want to say is that that failure is not due to Bavi.
I explained it here in detail.
For Bavituximab to fail it would have to NOT meet the trial design goals for the bavituximab arm while the parameters of the Control Arm are ALSO in trial design boundaries.
Here the control arm patients get Docetaxel+Placebo and outperform ALL historical data of patients being treated with Docetaxel alone that was used to set the clinical trial boundaries and expectations for that control arm. Hence the control arm was NOT in the clinical trial boundaries. CEO KIng even said "Dramatically outperform" I translate in "Dramatically out of trial boundaries"
So you could say: SUNRISE failed, not Bavituximab.
However, I do understand that currently there is a wave of attempts to make PPHM shareholders believe Bavituximab failed because that would reduce future potential and possible investment in PPHM. However, we can not let such statements pass without providing the right perspective and the details. One liners are becoming less popular these days given the importance of the subject.
However, in the more sophisticating assessment, that is including the COMPLETE information that PPHM has provided in the PR and Conference Call, what many poster want to say is that that failure is not due to Bavi.
I explained it here in detail.
For Bavituximab to fail it would have to NOT meet the trial design goals for the bavituximab arm while the parameters of the Control Arm are ALSO in trial design boundaries.
Here the control arm patients get Docetaxel+Placebo and outperform ALL historical data of patients being treated with Docetaxel alone that was used to set the clinical trial boundaries and expectations for that control arm. Hence the control arm was NOT in the clinical trial boundaries. CEO KIng even said "Dramatically outperform" I translate in "Dramatically out of trial boundaries"
So you could say: SUNRISE failed, not Bavituximab.
However, I do understand that currently there is a wave of attempts to make PPHM shareholders believe Bavituximab failed because that would reduce future potential and possible investment in PPHM. However, we can not let such statements pass without providing the right perspective and the details. One liners are becoming less popular these days given the importance of the subject.
Peregrine Pharmaceuticals the Microsoft of Biotechnology! All In My Opinion. I am not advising anything, nor accusing anyone.
