$IMNP ~ Eotaxin-1 causes eosinophils (a type of white blood cell involved in inflammation and allergy) to migrate towards sites of inflammation where they become activated and release substances that result in tissue damage and enhance inflammation. By blocking the effects of eotaxin-1 on eosinophil function, Bertilimumab is a promising clinical stage candidate for a variety of inflammatory conditions, including Ulcerative Colitis, Crohn’s disease, Severe Asthma and Bullous Pemphigoid.
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