NorthWest Biotherapeutics Inc (NWBO)

[Alextwolfe]

I see what you are suggesting -- interesting theory about the meaning of the yellow versus red lines on slide 7.

I have come to realize after thinking about slides 7 and 10 in relation to Pyrr's inclusion criteria change confounding scenario, is that his scenario is actually impossible because you cannot fit it to slide 7. I think Anhe and dwigg were getting at this same point earlier: look at the distribution of patients still alive (green bars slide 7). We know that 1/3 of the green bars are Method A (9), and 2/3 of the green bars are Method B (18). At least the longest surviving 12-13 green bars must have started the study prior to the (alleged?) inclusion criteria change, since they are alive now and on the study for 14+ months. So in Pyrr's theory these 12-13 patients must have been all Method A. But we know this is impossible since only 9 of Method A are alive (as we are told on slide 10). Hence at least a few patients who enrolled in the study prior to last summer MUST HAVE BEEN TREATED WITH METHOD B, which proves Method B was in play prior to the start of the alleged inclusion criteria change.

This isn't the only flaw in his confounding scenario but its one blatant one.