Jess, it wasn't one, it was three: Rida- was failure 1, Pona-was failure 2, '113-was failure 3 as they forced a high dose to try to cover EGFR and ALK+ at one time, dropped EGFR, then kept the dose too high for ALK+ so they had to stop the trial and start over, losing 18 precious months.
As 2da and others have commented, Ariad is a terrific research and discovery company, but really have no clue on how to bring a compound to the market. There is nothing wrong with this, you play to your strengths. The problem is the CEO is in never-never land and has a dream that Ariad is the next Celegene. That simply can not happen, and is dragging down the company.