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Thank you for your kind words "zzaatt"! It is a tough ride being on the "PSTI Train" over the years- and at my age- I need more and more omeprazole :).
This move has been a good one for me. I know the potential is enormous IF they can get their act together. But the risk is too high for me at this point.
I do wish all investors the best outcome. It is a roll of the dice and the potential is huge.
GLTA!
ERIK
I was invested for about 8-10 years with PSTI. Sold around $6.50 and sold it all the day they announced they would no longer pursue CLI. At that point I realized that a 3-4 Billion Dollar potential was gone. They eventually did this same move with other indications as well (ARS, Covid Brueggers,China Deal, Preeclampsia etc.) and for me, that was the last straw. Since this time, except for one potential ( Hip Replacement), they seem to have abandoned all Human Clinical Studies and Use for their Products.
All that is left is Food Technology which appeared out of nowhere 1-2 months ago?
This seems to me an act of Desperation- and 1 year ago, ALL of their eggs were in the Clinical Disease State Management Basket and they have abandoned all of them.
I have stayed purposely away from this board watching the responses but today I had to speak up. I wish all of you the best with this stock. Me? I am back to large funds and bonds... Best of Luck!!
Me?? I just checked with Fidelity- 9 years holding for me... Either it's- raise a glass of Champaign or Socrates' Hemlock :) in a pretty short period of time. Best of luck.
Thank you skaye19- I figure if the news "Ain't" good- it might drop below a 40% drop in price- like $5? And I guess that this falling knife might bounce off the floor to close higher than when my Market Order was filled! Arghhh- the pain... 2 more weeks of this??
Anyone else trying this approach?
Stock expert Question- A Stop Loss (Just in Case)- I just put one in at 3:44 and the price went negative?? Can a stop loss order generate action?
I just feel that this really is a do or die scenario in the medium time-frame for PSTI and I do not want to go back to the $3.00's ever again.
Stop loss was placed at $7.25...
Thoughts??
ThunderStatement Thunderforce1 !
I have another "Funny Feeling" today... When you see a MAJOR Buyer ARK buy on the way up even at this price, you have got to believe that the current price will be going up. They obviously think so. Adding to this- the CLI timeline for an announcement- My prediction $33 by 12/31/20. GLTA.
The Melon!
Things are starting to move here- I mean ARK et al- buying hand over fist on every opportunity- and the meeting tomorrow- with higher than normal volume. I like the price movement recently- we just need that ONE (Please just ONE) announcement on a completion of COVID or CLI or Hip Surgery endpoints, and it is over.
I think PSTI is taking a very safe route to release data. They use to release animal/ mouse studies all the time! Look what has happened to MESO and other stem cell companies- Zilch from the FDA.
I know that many are calling them inept etc.- but, they did say they will stay silent on these studies until completion which is rare in the industry- But Stem cells are still very controversial with the FDA and thus the S L O W release of data.
I am just hoping that this is the reason and the these purchases by "Insiders" :) are based on the knowledge and confidence that they have.
GLTA
Interesting- PSTI's subject is speaking directly about Compassionate use. There must be some updates on numbers of treatments or hopefully some encouraging efficacy/safety data... Fingers crossed.
It's pretty close, but I don't think so- Looks like there may be some ethical issues according to Wiki with embryos-
Here is a quote from another article Published June 2020- (Embryo= Placenta?):
"Fatima al-Kaabi, Head Hematology and Oncology at Sheikh Khalifa Medical City and Co-Principal Investigator of the stem-cell program, had explained how UAECell19 works.
“We have isolated a type of primitive stem cells, called embryonic stem cell, which researchers think carry regenerative potential. They belong to that type of cells that are capable of regenerating damaged cells to reduce lung inflammation resulting from COVID-19, and thereby can help these cells to self-regenerate,” she said."
Here is the article:
https://english.alarabiya.net/en/coronavirus/2020/06/26/UAE-stem-cell-treatment-helps-1-200-patients-fully-recover-from-coronavirus-effects
Where is PSTI in this mix? I do not see a Presentation- I do see Thermal Fischer... I hope we are mentioned...
Thanks FDA- It's Nice to see an actual prepared clinical paper published. The "P" values look really tight. And though it is not those "Large and Controlled Studies" we all want, it is a BIG step in outcomes. There is a lot of data that can be gleamed from the paper. Certain Quotes that I find quite enticing:
CRP Levels-
“Following PLX-PAD treat-ment, CRP levels decreased in all eight patients starting as early as 24-hour post-treatment and continued to decrease throughout the study follow-up period (Fig. 1A)… and by day 5, it had fallen by 77% to 56.0 mg/L (p < 0.0001).”
“Improvement in Chest Radiographs Following Administration of PLX-PAD”
“In addition, MSCs are known for their powerful antifibrotic effects and may alleviate lung fibrosis (30, 31).”
“therefore, it can be safely used in COVID-19 patients without being a further target for SARS-CoV-2.”
“Both the anti-inflammatory and immunomodula-tory properties of PLX-PAD may explain reductions in kidney injury leading to reductions in creatinine levels.”
https://www.pluristem.com/wp-content/uploads/2020/09/Placenta_Derived_Cell_Therapy_to_Treat_Patients_September2020.pdf
It does seem that they have engaged and backed out of many indications: COPD (United Therapeutics)/ Preeclampsia/ Acute Radiation Syndrome and now Covid. Finish Line anywhere??
Over the last 9 years, I get this same "Feeling" every time they release some limited information. Either this is a scam- or this is the biggest kept secret in Biotech. What you say? I guess just keep the faith (again).
Yaki sends out a letter- and just like the last time the PPS drops.
I think some of you know this, but, as an employee, my wife was granted stock shares (options?) throughout her tenure. This was true with every other employee at the company at certain times. These were varying amounts (per employee's level) as extra incentive. They thought nothing of it for many months, until the adjusted pre-split price eventually went to $1,200 a share.
Come on PSTI- you can show the world what a game changing effect you will have on all of us. So far, except for lack of candor and inability to get to at least one finish line, the efficacy and tolerabilty have totally met my expectations.
Now everyone get out your calculators and dream. There is still this possibility.
I also swear I heard him say yesterday- that the therapeutics have shown 60-85% improvements- Hmmm I have heard that statement before- It HAS to be one of the stem cells...
Has MESO, ATHX received a similar expanded access designation from the FDA above their current studies? If not, yesterday's announcement is much bigger than the current price of the stock.
All of this recent information is very intriguing...
I sometimes, out of curiosity look to see what those "Betting" on the future PPS for PSTI might be-
the calls are looking very promising-
the majority calls for Sept are: $14
October: $15
December: $23
March 2021: $16.
A very exciting time... I wanna be GREEN soon!
https://marketchameleon.com/Overview/PSTI/OptionChain/
If this is True- This FDA Approval bypasses the crippling Placebo Controlled Study. This looks like there is real confidence in PLX-Pad Efficacy...
Looks like SEVEN Hospitals are or will be recruiting for the study! Two are already recruiting now- I believe it was One last week- see the link with the side by side changes TODAY at the bottom of the page (highlighted in Green)...
https://clinicaltrials.gov/ct2/history/NCT04389450?A=1&B=6&C=Side-by-Side#StudyPageTop
If MESO fails tomorrow, what impact will this have on PSTI? We know the PSTI has the approvals on quality yield in manufacturing, and the clinical trials look promising. Many approved medications have modes of action that are not vlearly understood. Very interesting scenario tomorrow. Up or down for PSTI???
I appreciate your insight FDA- I may have knowledge on efficacy and tolerabilty etc.- but judging from your comment- the market also feels this might be a good thing- at least today!
Board: Is this emergence of Clover a good or bad idea when it comes to the future of PSTI? So far, in the short term, it looks good for small gains in share price.
Thanks MrTrader129... I HOPE so... "Pay no attention to the man behind the curtain!"
Despite my Pessimism- PSTI looks sweet after hours. 15 k shares traded!
https://old.nasdaq.com/symbol/psti/after-hours
Typical of PSTI- Info hidden from public and then Delays. Are they sort of a shill?
(Definition- "an accomplice of a hawker, gambler, or swindler who acts as an enthusiastic customer to entice or encourage others.")
So, PSTI has an advantage over MESO and ATHX in the treatment of Covid? It seems to me that they are all on even par to get recognition. If anyone feels we have a "Leg-up" I would love to know!
Thanks Jamie9... I have been here owning PSTI for about 10 years now. I did add 30% more back when it was in the $3.00 and that helped a lot. But I do see a repeating pattern- Holding long- but the beer has been poured!!
Yes... This is very disturbing. "In a few days" we have heard on other fronts as well. Just how far are they progressing, or are they just "Blowing in the Wind"?
The price action is definitely a result of missed dates. Over the years, the really large spikes in the PPS are based on a here and there stories of success- We have been waiting patiently for their "Promise" for results particularly in Stage 3 Studies (Hip, CLI). Let's not forget that BARDA "postponed" the study on ARS, and the Fukushima results are seemingly missing as well for quite some time now. And a gentle reminder... let's not forget United Therapeutics ending the collaboration with PSTI on Pulmonary Hypertension 5 years ago.
https://www.globenewswire.com/news-release/2015/12/08/793824/0/en/Pluristem-and-United-Therapeutics-End-Licensing-Agreement-Report-Positive-Data-in-Pulmonary-Arterial-Hypertension.html
Something just doesn't smell right.
I wish ya the best "XWAVXALMIMAN"- You bought in at the right time- Me? 8 years and adding. I was in pharma for 27 years and I remember "Syntex Labs" in the late 80's saying the future was Biotech with disease modifiers- verses drugs that "Fool" the body (Blockers)- Really looking forward to see if this company can finally break past conferences, patents, and unfinished Stage 3 clinical studies. Being small has it's disadvantages as previously mentioned but great potential as well. This new Covid thing will FORCE the company to release data ASAP finally. Good luck!!
Yes I saw that. It probably is a translational error. However, it does mention PSTI product. And the success rates. Just another country intrested in their products.
Argentina and PLX-Pad? I just did a news search and found this-(Translated through Google)- looks like it was published 14 hours ago.
Interestingly, part of the article is news to me. Has anyone else seen this??:
.................................................
"Stem cell-based treatment is already applied in Israel with a 100% survival rate.
In recent days, the Israeli Ministry of Health approved the treatment of sick patients with stem cells of COVID-19, who had a recovery rate of 100%. The news generated great enthusiasm among scientists who research and work with regenerative medicine in our country.
The treatment that is being carried out in three Israeli clinical centers is known to be saving the lives of critically ill patients, with excellent results. The proposed treatment includes intramuscular administration of PLX-PAD, which uses cells derived from the placenta, for severe pneumonia resulting from COVID-19 and to prevent the deterioration of patients towards acute respiratory distress syndrome (ARDS) and sepsis. . The stem cells are extracted from the adipose tissue of the patient under treatment.
Currently and motivated by the excellent results, Argentine researchers and scientists from the Regenerate stem cell bank are proposing to the Argentine Ministry of Health to collaborate to advance research and use of this treatment in patients in our country as soon as possible."
.....................................................
https://translate.google.com/translate?hl=en&sl=es&u=http://www.sn24.com.ar/noticia/ciencia/19678-coronavirus-investigadores-argentinos-proponen-el-tratamiento-de-pacientes-graves-con-medicina-regenerativa&prev=search
Tomorrow's Signing...I believe that today's downward spiral and 50% recovery is based on tomorrow's event. Manipulating it downward to reap the benefits in 18 hours...
The other 2 "Competitors" MESO and ATHX are in positive territory today- We should be as well- so hold your breath and let's see how this plays out over the next 48 hours...
PSTI= Tortoise, MESO= Hare. No question over the long haul they will eclipse "the others" with their clinical success and the indications they are targeting.
Mesoblast= Bone Marrow right? I think I will take Placental Cell- Don't make give you stem cells from my bones!
Bought another $7500 today just as the news broke- My dollar cost averaging WAAAAY down now... After all of these years, I am starting to look smart in my wife eyes
Our Dream and Mine. I don't know about you, but, I have always had faith in PSTI- and I have had this ongoing dream that because their products are insulated from the Market "Going-ons", that someday PSTI would support our financial holdings as a whole, when things head south.
I feel the stock market is heading for a very bad scenario soon. It hasn't been easy over the years with Pluristem. FINALLY- it is nice to see that so far, over the last few weeks, this company (out of the blue with an completely undiscovered new possible indication), has supported this downward direction of the overall market.
GLTA
And they Probably have extra $$$- It's a Program of Faith- and I think this is what we all need here on this board!
PSTI was just mentioned on 700 Club on their CBN news section. We know they have published this in print. This one was via television. Come on world... catch the wave!