Just like their London lab, right? I don’t think anyone really has a clue what went on there.

FDA National Priority (CNPV) Voucher Program Submission
In parallel, SignPath submitted a justification package for review under the FDA’s new National Priority Voucher (CNPV) Program, which rewards development of therapies targeting urgent public health challenges, including conditions with severe unmet need such as glioblastoma.

>>“This is a significant opportunity for the program,” said Michelle Comas, Chief Operating Officer of SignPath Pharma. “The combination of Orphan Drug Designation, Fast Track submission, and the CNPV application positions LipoCurc™ for a potentially accelerated regulatory path as we prepare to meet with the FDA in early 2026.”

https://www.mywabashvalley.com/business/press-releases/ein-presswire/875676991/signpath-pharma-announces-orphan-drug-designation-and-fast-track-submission-for-lipocurc-in-glioblastoma/

That’s big!

https://news.nm.org/faster-approach-determines-brain-cancer-treatment-is-working/

>>Immunotherapy has transformed cancer care by enhancing the body’s immune response to better recognize and attack cancer cells. While immunotherapy has been shown to be effective in many cancers, including lung and breast cancer, it has shown benefit in only a small number of patients with glioblastoma, the most common and aggressive type of primary brain cancer.

https://news.feinberg.northwestern.edu/2025/12/17/noninvasive-treatment-boosts-immune-response-against-glioblastoma/

Through Toucan would be my bet.

There’s Real world evidence and there’s anecdotal real world. I’ve seen maybe half a dozen L cases in more than a decade that seem more than just anecdotal. 🤷‍♀️ That’s not going to cut it, IMO.

900M to keep the lights on! 😂🤕 Yeah, because that’s not the bonus in itself. Amazing that LP would be so bold as to throw the “bonus” package in too. Bet she says Hey, with these dummies why not, let’s try it! For anyone who shows up, I’ll give them lobster rolls just to keep their mouths shut. LOL

Here’s the latest on the subject.

https://futurism.com/future-society/young-kids-using-ai

This is crack to AI. 😂

And shareholders will end up with a CEO CFO running UK manufacturing from the U.S.? That works how exactly?

>>It's make or break for NWBO -- it they fail they'll become a contract manufacturing company.

Makes sense she’d wait until the second to last day of the year to explain it to shareholders. 🙄🤷‍♀️

>>she indicated that we'd be a very different company by the end of this year

Then it’s a lucky thing for shareholders that NWBO is involved with neither.🤔

>>You "hit that nail on the head". BP and Oncology has been a scam for a long time

I bet she’s saying right now “You mean some are actually coming?!!!” Maybe praying for a blizzard.

I’m sure they’re doing everything possible to make LLM’s seem as human as possible, but all they really do is sift through text and splice it all together.

Must secure the vote!

Danish is its dope peddler. 😂

Cleveland Clinic has nothing to say about L.

https://consultqd.clevelandclinic.org/emerging-technologies-in-brain-tumor-management-podcast

It was but I’ll leave that to the chemist.🤷🏻‍♂️ But as an NWBO investor you should probably feel some outrage that no BP came forward to assist DCVAX or children were treated with L. 🤷‍♀️ I’m sure the DietDoc is putting together a piece right now explaining how DCVAX gets around all that. 🙄

>>The part about the “crisscross” was kinda fascinating, too

Whether the share price goes up a little these last two weeks may depend on when it’s believed votes have been secured?

LP may not have counted on mRNA being the UK’s darling and making sure nothing stands in its way. That’s being incredibly generous to DCVAX and LP, of course.

Probably find it was a strong day for dilution with yesterday’s NICE pump?

WHERE’S THE BEEF?

I take it you read that sad (but hopeful) article. Can you explain why similar articles haven’t been written about DCVAX and why no pediatric trials or offers from BP?

>>There are thousands of graves that sat and in mute testimony against this endlessly tweaking and CYA mentality. Again this is a clinically safe treatment and even the worst detractors arguing in bad faith admit that!

LP’s game plan seems to be about taking decades to help change the regulatory landscape instead of running a quick decisive trial. She may be waiting for GuruGary to run the FDA?

Wow, zero responses. Remarkable. 🙈🙊🙉

You don’t get it, the increase in authorized IS the compensation package.

>>But in an unlikely move, in fall 2024, Merck & Co. decided to acquire Modifi Biosciences in a $1.3 billion deal. While a pharmaceutical giant like Merck would not be typically interested in a drug still in its early stages of development like KL-50, its unique mechanism and potential to also treat other kinds of cancers had caught the company’s attention. In its hands, if all runs smoothly, Bindra says KL-50 could become available to patients as early as next year.

https://medicine.yale.edu/news-article/for-families-battling-brain-cancer-new-treatment-brings-hope/

I’ve always suspected the FDA felt the parallel study group and compassionate use ruined the blind.

First, it’ll be NWBO news not MHRA news coming to you, and second, you have nothing solid to base this on. The wait could go on another year or just disappear altogether, especially if LP exits.

>>We are beyond any shadow of a doubt close to some MHRA news

Just don’t see these kinds of images with L. 🤷‍♀️

https://www.instagram.com/p/Cv8FYYvu2nE/

Yes. A customer of Advent’s is now a customer of Northwest’s, or at least shareholders can hope. 🤷‍♀️

Fantastic news! Could help several of my biotech investments. Might even help L if they have an actual Specials record worth looking at?? Although it’s likely opening the door for a lot more shenanigans overall. We’ll see.

Could also be that Advent is now a U.S. company and needed to be updated?

Wouldn’t Sawston need to be licensed to supply any living cell therapy product for any customer and trials?

SurVaxM is already running their pediatric trial so I suspect it’s going well.

https://clinicaltrials.gov/study/NCT04978727

Every day. Have you found anything more on Tuttle…I mean Duffy? Was that him moving on to a T-cell therapy or someone else?

….Ex, please remind me about patient’s provided steroids in both the Plll and SurvaxM’s 2b?

Could be a red flag but I suspect it’s doing well. They’ve figured out ideal delivery in terms of timing and dosing. I suspect LP wishes she had a do over on the Plll.

https://physicianresources.roswellpark.org/news/roswell-park-announces-positive-progress-in-clinical-trial-of-novel-immunotherapy-survaxm

Today’s password is “DE-INDENTIFIED”.🙄🤷🏻‍♂️

https://www.tpr.org/podcast/petrie-dish/2025-12-14/science-medicine-a-breakthrough-for-glioblastoma-patients-that-may-lengthen-lives

But somehow LP can’t find the cash for any trial.🤷‍♀️

>>CRISM Therapeutics Corporation announced the successful closure of its Retail Offer, raising £59,610 through the sale of 662,332 shares. The funds will support the progression of a Phase 2 clinical trial for irinotecan-ChemoSeed in glioblastoma patients, with dosing expected to begin in Q1 2026. The new shares will be admitted to the London Stock Exchange, increasing the company’s total voting rights to 51,735,266.

https://www.tipranks.com/news/company-announcements/crism-therapeutics-raises-funds-for-glioblastoma-trial#google_vignette