I hate to say this but I believe that unless Dr. Missling sells a chunk of shares in “placements” to thwart this attack we are going to be suppressed going into and after approval. The longer this suppression lasts is also an indicator we are moving forward with a minimalist partnership. Revenue within sight will break this crapshow instantly.
Perhaps a unknowing announcement of a large upfront payment from a partner will catch them with their pants down…kind of like the freeze during the reverse split and then uplisting to the nasdaq did.
Boi, with the shorts digging and the likes of BR, SS, snd others continuing to load up shares Q over Q, is it too far fetched to think they are in bed together? Ive heard multiple times that the leveraging of the stock market through derivatives is currently hanging out about as far out as one could go. The shells are moving faster and faster to hide the ball. I think BR would be at the center if it all with the solid IP, lack of secondaries, and effectiveness we hold.
Just too coincidental every reporting period for me on both positions.
Dr Missling riding high coming into the home stretch of this journey to approval and ultimately to market. He has many of the top guns riding shotgun surrounding the payroll as their are bandits everywhere watching, trying to time when/where they can pin him in a “canyon” or at a “hilltop”. Some say he is careless and not capable of getting us all the way, but as for me, when looking around, I see we have made it the deepest into the uncharted wild west territory of the Alzheimers frontier. Trailblazers, often misunderstood but non the less focused on the ultimate goal at hand not sweating the small arms fire (AF ilk and the like) along the way. Many will look back and say “dam, what a hero!”
Big payday ahead longs. Keep your heads down and a swift speed about you, approval coming soon!
Doubt reaches an all time high further exhausting already worn out long retail right before the big bang. Happens every time, Im ready with popcorn and have been accumulating for right at 10 years now.
Those that loan shares are complicit in the takedowns imo. Its totally legal but imo morally questionable when the act helps to aid and abet the straddling and suppression of companies trying to bring such a life saving drugs to market.
Pure evil. Acts are either “for” Him or “against” Him, no grey area.
“ but but but everyone does it….and and and most bio companies fail!”
Ihid is this where one many LLC’s are set up to accumulate and then sell for a takedown? Very low volume with such a large drop and just look at how they get scooped up. Add in the unfair ability of the big boys to buy shares fractions of a second ahead others (and sell) which was covered 6-8 years ago. This was covered by a 60 minutes piece highlighting the fact that large cables were being installed across the Hudson by trading companies and nobody understood why until medium HF’s were being “circumvented” when trying to buy and sell.
assuming commercialization efforts are not botched,
Yes, much focus is being placed on rollout. Also small but important steps like labeling too. Any mistake can delay by months giving shorts a quarter or two to manipulate even more.
Well said Boi. I think many have their vision clouded. We need approval and with our BOd’s experience and the right partner I think 2 yrs max we hit 40-50% market penetration if not more. If Dr. Missling was smart, if the countries get nit picky in their negotiations then let them put their population on the mabs for a year while other more welcoming countries get “first rights”.
Amazon, Merck, and Takeda would be a good start geographically, maybe JNJ and Partex with their genomic testing abilities.
Put your best foot forward and lets hit the ground running keeping everything as simple as possible.
No one thinks that being the 3rd largest pharmaceutical company in the world, by market cap, is a crazy fantasy?
Upon approval, our “lag time” to build out our product is past tense. Depending on how Dr. Missling and our most excellent BOD move forward, our market penetration will/should be way different from days of old where salesmen/women have to door knock. Yes this will still take a year or two for the world to wake up but in this age of digitization, ease of manufacturing, and administering of the drug, you have to admit market penetration should be in full swing within two-3 years tops.
When we looked at Microsofts market penetration as an example it took a decade of giving away their product to penetrate and maximize sales allowing for 9 forward splits over a decade. This imo will not be the case here. News travels fast in this day and age and all patients, WORLDWIDE, will need to hear is safe, daily oral pill, and great results and pressure will build.
We will either stay independent with a well crafted plan (for about 2 yrs) allowing for maximum MC increase from sales and a pipeline maturity with a monumental buyout in the end or a BO price upfront of 30-40 billion. The complete genomic data is/will be forthcoming and will be irrefutable.
Great points Sab and trading has only gotten more sophisticated with AI in aiding and abetting the manipulators. Algorithms track in nanoseconds data on every level. Tech geeks for a decade have become instant multi millionaires and HF’s best friends. The sad part is that every designed manipulation is to extract money from retail and other less “connected” HF’s all in the name of greed.
I wouldnt trade places with any of them for all the money in the world.
Mathew 16:26
“What profit would there be for one to gain the whole world and forfeit his life? Or what can one give in exchange for his life?”
The EMA would then decide on what the path should be for the lesser performing group(s), once the data had been collected over an adequate period of time.
What a wonderful problem to have for the EMA.. Approving a drug that is easy to administer, has a great safety record, and highly efficacious for 70% of its users.
The mabs dont stand a chance upon our approval. That is the real battle behind the scenes, who is going to approve us putting their neck out there and risk losing multi millions of dollars of scientific “funding”.
I am unhappy that this company has such incredibly good therapeutic assets but they squander their opportunities to capitalize on them. SMH.
If they ran another ph3 our stock would be in the $3-$5 range from the crooks squeezing Dr. Missling at a time when he needs money. Ghe 130 million would not be enough and would being us dangerously low.
If Dr. Missling gets the ball across the goal line with EU approval he/we win!
So Blackruck continues to increase its holdings, now over 8%, as we see these suppressed MC prices of AVXL? And some say there is no collusion.
How many fake LLC’s are out there holding a few hundred thousand/million shares ready to dump them when its time for a takedown or even worse a takeover.
This weeks trading action is the same as 100 other weeks. There is very close monitoring, by shorts/those interested in controlling our stock, of Anavex’s PR’s before financial or medical conferences. This is true of the clock stops and any other points in time up to EMA approval. This is widely known that companies do NOT risk influencing/risking their application process and or bringing about a lawsuit during this time period. On top of that everyone knows Dr. Missling is very conservative in nature as a leader, good or bad.
All this said it really speaks volumes as to the desperateness of shorts continuing a weak narrative correlation at moments in weakness of the stock price trying to scare retail. This is why it is very important imo to not try and be the 1rst poster, for the 52nd trying to predict the beginning of the next run up in price. It either is a case of drmrntia setting in or it almost appears to be in collusion by longs trying to pull in new money so the shorts have “food” to harvest along the way.
Put the phone down, step away from the computer, get outside and take a few deep breaths on a nature walk. If it was shared with us by a doctor that our life would end tomorrow, what would be most important to us? That is what is truly needing our focus. Before we know it Christmas will be here!
I'm trying to re-think about both the sellers and buyers on Friday;
SAB I wouldnt think about it too much. I forget who brought it up recently, and whether it was on Stocktwits or here, but how easy it is for a fake LLC to be set up aqcuiring shares slowly over time with the MM’s giving preference to their buys only to be used to “sell” 1 million or 1.7 million shares (pick a number) to a large short in a dark pool. It would give all appearances that there is a problem with the company and in this case somehow the stock dropped. ALL ARE SHENANIGANS!
Approval is coming, barring a complete market meltdown we will go up and by quite a bit. You can bet your bottom dollar the shorts have every ear to the ground they can bribe looking for THE exact date!
but Anavex did not show up on their doorstep with an NDA.
Exactly my point, just think about it what your saying. A US based company, took a chance running an Fda newly designed ph 2a, closely designing the ph 2b/3 with the FDA input and NO NDA application.
This is Alzheimer’s after all, the holy grail and after 20 years of a wasted Mab blackhole, Dr. Misslings chose to move to the EMA. Point made.
Boi you can not deny the Biden/Obama 2.0 admin fully embraced the mabs. They double and tripled down on yet another failed policy. Reward the entrenched 20 year failed mab theory.
They had every opportunity to “embrace” the Anavex ran, Fda designed/approved early Fda ph 2a and ph 2b/3 trials. They actually succeeded in providing what the gov program designed the trials for and yet they gave them a cold shoulder the entire way hence Dr. Misslings start in the AU and then ultimately the filing in the EMA.
This will be just yet another failed policy and a wasted opportunity for the OBiden admins. I say to DT, RFK Makery to run it up the giant flagpole as high as you can and be let it wave proudly! No other way to see it, imo.
I think it seems that the market maker is the long to me and acquiring today for a very large BUYER or BUYERS....
Love it! The 30,000’ view to close the week ahead of possible news in the next few days/weeks/month!
10 years now, whats another 2-3 months max? Todays silly games even a year from now, should we still be independent, will look ridiculously low compared to what we will see.
Right now it is anticipation of those that determine price. Long and strong here.
AV, I agree! There has been a lot of side show circuses along the way that try and create drama. Their “acts” create emotional challenges for longstanding longs like me trying to separate us from our shares with “the sky is falling” type scenarios. Too NUMEROUS to count!!!!
Outside of a complete market meltdown, post approval, I think a partnership, again, post approval is the key. Dr. Missling will not be letting a partnership cast doubt post approval in any form. The partnership will be forged with drug already stockpiled (at least a years supply) with labeling approval, very closely watched as this is another opportunity for devious mishaps to take place delaying roll out, and imo very narrow windows for executing market rollout. In other words Dr. Missling and management will be on top of this pursuing a clear, quick and precise path from manufacturer to patient focus.
We havent been advertising the ease of administration and patient centric aspect of our drug for going on 6-8 years now for some bp to step in and “take a dump” on our rollout while trying to lowball us on a buyout offer. I GUARANTEE you Dr. Missling will be 5 steps ahead of them in “ fine print” on the deal, just like the accelerated share sale on a price spike we took advantage of when the crooks controlling the HFT cycled us into the $30’s.
God willing I have very grand plans for profits from approval, the question is when and what does He have planned for me?
In reality long time longs are sitting at $2.05 per share pre split and $40 pps equates to $4 per share so unless you continued to load the boat in the $7’s (70 cents pre split) the stock is getting back to even money after averaging down for 5 years.
After watching and reading todays PR about the recent AD conference I get the feeling that Anavex’s management view has gained more confidence and turned the corner. These look to me more like marketing tools rather than data sets. It is selling the patient centric appeal vs current SOC. Who isnt going to want to take a once a day pill to offset AD symptoms. Im ready to take it now to prevent AD. Please, where do I sign up for a AD prevention trial, sleep improvement trial, retinal degeneration trial, prostate improvement trial…..USE ME!!!!
OAN I get the feeling Dr. Missling is preparing for the definitive knockout blow with a partnership PR. His thoroughness and methodical release of these informational videos which speak to millions of laymen like me are all part of a groundswell plan ahead of CHMP recommendation and ultimately EMA approval.
Let the shorts rejoice in their constant pillaging and fakery “the pill doesnt work” psychological bullshet for now, our market cap increase will follow longs just hold on tight.
Who is still loaning out shares? Its a hypocrisy to complain about the share price being in the gutter after every great PR when your aiding and abetting.
Anyone else having difficulties with stocktwits this morning? Its not loading up.
Also, I know its a tall order but long should realize that talking up the share price, ahead of the CHMP meeting, for the 53 time will only set themselves up for frustration. Its a ling way to approval and the world IS teetering on a financial meltdown so lets all let it play out with out “to the moon” pps predictions, including myself! Lol
I think your estimate gives Anavex the short end of the stick, given what it is capable of doing ... plus, this does not give any credit to 3-71 et al in the MC.
This is exactly what the “fair and balanced” market wants to accomplish but cant due to the current share holding structure. “Middlemen” make bank on secondaries, shorts make bank on trapped longs, and the acquiring company comes in and cleans up. Currently all that “they” can accomplish is to suppress the MC and acquire as many shares as possible before EMA approval. Dr. M would be a “sell out” in my book if he let go of A2-73 and A3-71 for 13 Billion. After all, we are only addressing a 265 billion market.
If later they give us an offer we can't refuse, we might sell, +150 bucks a share, maybe.
With all due respect $150/share or 13 billion buyout would be for Schizophrenia or AD and would not take into account future revenue. A buyout for 15x our MC with projected revenue is a lowball. There is a reason Dr. Misdling is sitting on a stockpile of medicine and I believe it is to accelerate the sales process upon approval and partnership announcement.
When Anavex holds all the IP, trial design, EMA submission, and manufacturing, it takes a lot of “acquiring” companies control away and therefore imo the buyout price will be 30-40x and only after sales can be factored in, not before.
Remember too the myriad of trials lined up to go with successful POC phase 2 trials, I think there is even a red bow on a few. BP BO candidates would be fools not to offer at the 30-40x evaluation listed above.
Personally if I were Dr. M I would wait 2-3 years after a few more trials are completed and the case is made for prophylactic use. Thats when the real dough is rolling.
After listening to most of the press release I am highly positive that there is absolutely NO FRIGGIN WAY this administration is going to allow Europe to approve the first ever efficacious orally administered drug from a company right here in the US…..zero chance.
I think we have a spot in the CNPV and it gets announced before the EMA makes the final approval.
President Trump likes to be first and this will be bigger than todays announcement and will also be a first.
Cassava Sciences Form 4 Filing Shows CEO Richard Barry Bought 237,941 Shares Of Stock At An Average Price Of $2.25/Share Benzinga 4:22 PM ET Sep-22-2025 - SEC Filing
One of the directors had made significant investments in Sava stock open market more that once too. In one case he tried to put a “floor” on the drop at much higher prices, I believe in the low teens. How did that work out for him?
Typically its a definite bonus to have insiders buy but in SAVA’s case it always appears on the surface as yo me as “gimmicky” at best.
Anavex’s data will speak for itself and the shareprice will correct accordingly imo.
Looks like the bottom might be in for this psychological cycle. If so we will see the stock rise in the coming days/weeks. Just a reminder, the rise, if it does, has nothing to do with the science, total disconnect and is designed to hype longs.
do you really think the company is worth only $750 million
Absolutely not. Its a game of chess though right now with BP and HF’s and MM’s. Anyone who thinks these guys “circles” dont hobnob together at social gatherings are fools.
Either longs are way off base in approval chances or the manipulation pressure on our share price will evaporate at revenue vision upon approval.
I might add the only reason we are at $8-$10 per share is due to our CEO’s experience in financing. He loaded the bank during the run up. It was almost like 50-60% of the weight was lifted off his shoulders not having to worry about financing our path to market.
All this being said yes, we do still need approval and our chances are very high given the unmet need and safety.
This is the typical 5 yr stock chart for a young biotech. Look at the high volume hockysticks. Shorts covering at an all time low and then the second would be, what, the transfer to an interested buyout entity? Next would be the buyout price of $4…?
Too funny. Look at our 5 yr chart and compare, again, its painful at $8-$10 range pre approval but the alternative is to be at $2.50 per share awaiting approval.
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