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Optigenex Inc (OPGX)

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Optigenex, Inc.                          

51 Newark St.
Suite 501
Hoboken, NJ 07030
Phone: 201-355-2098
Fax: 212-905-0191


Optigenex, Inc. is an innovator in the field of advanced DNA sciences. Its core product, Activar® AC-11®, is a patented product designed to manage the effects of aging and cell damage by supporting the body's natural ability to repair and maintain its DNA. Optigenex is committed to providing life-changing products which support the body's natural defenses against the effects of DNA damage caused by environmental and lifestyle factors.

CEO Daniel Zwiren:

Mr. Zwiren has over 25 years of management, financial and operations experience in several industries including; healthcare, financial and software services. Mr. Zwiren was Managing Director of Valued Ventures LLC from August 2004 thru January 2006. Valued Ventures LLC, an advisory/capital procurement firm located in NYC specializes in the biotech and technology industries. From January 2003 to July 2004 Zwiren served as a private equity advisor at UBS New York, NY. Mr. Zwiren was the Managing Partner of Osprey Capital LLC, Ponte Vedra Beach, Florida a Capital procurement/advisory services company from January 2002 thru January 2003. From 1981 thru 1996 Mr. Zwiren held a variety of management positions with Lasser Marshall Inc. New York, NY an international institutional financial intermediary, including Chief Executive of the Capital Markets Group from 1989 thru 1996. Mr. Zwiren is currently serving on the board of advisors for the Global Flu Consortium in Washington D.C.. Mr. Zwiren holds a Bachelor of Science from Hunter College New York, NY June of 1978 and completed his MBA at Pace University New York, NY in January of 1980.
Share Structure:


  106,000,000  (Updated: 


Optigenex AC-11® (C-Med-100) Patent:

1. (7579023) Method of preparation and composition of a water soluble extract of the bioactive component of the plant species uncaria for enhancing immune, anti-inflammatory, anti-tumor and dna repair processes of warm blooded animals.
Optigenex, Inc (Hoboken, Nj) 
Pero Ronald W (Arlington, Vt)
Application Date: 2005-11-09
Publication Date: 2009-08-25

Clinical Study Abstracts And Summaries On AC-11®:

AC-11® Clinical Study - AC-11® inhibits TNFa production & scavenges free radicals
AC-11® Clinical Study - DNA repair enhancement of aqueous extracts of Uncaria tomentosa in a human
AC-11® Clinical Study - Enhanced DNA repair
DNA Repair as a Primary Molecular Target For Anti-Aging Therapies
LifeSpan topical skin creams - Clinical Trials and Research with AC-11®
Efficacy and Safety of AC-11® - Clinical Studies
A review of DNA repair and possible DNA-repair adjuvants and selected natural anti-oxidants.
A water soluble extract from Uncaria tomentosa (Cat's Claw) is a potent enhancer of DNA repair in primary organ cultures of human skin.
Formulation and in vitro/in vivo evaluation of combining DNA repair and immune enhancing nutritional supplements.
An active ingredient of Cat's Claw water extracts identification and efficacy of quinic acid.
Quinic acid is a biologically active component of the Uncaria tomentosa extract C-Med 100.
An extract of Uncaria tomentosa inhibiting cell division and NF-kappa B activity without inducing cell death.
C-Med 100, a hot water extract of Uncaria tomentosa, prolongs lymphocyte survival in vivo.
DNA repair enhancement of aqueous extracts of Uncaria tomentosa in a human volunteer study.

SEC Filings:  

Press Releases:


Optigenex Inc. Announces Expansion of AC-11(R) Sales in Japan Through Its Exclusive Partner Itochu Corporation

(01/04/10) Optigenex Inc. Agrees to Long-Term License Granting Promethean Corporation Exclusive North American Distribution Rights
(11/03/09) Optigenex Inc. Announces New Business to Business Web Site to Target Select Marketing and Manufacturing Companies in the Skin Care and Wellness Industries
(10/21/09) Optigenex Inc. Announces Supply And Trademark Agreement With Suracell Inc. To Utilize The AC-11 Trademark And Technology For Oral Supplements
Optigenex Inc. Announces Rollout of Activar® AC-11® Oral Supplements and Activar® AC-11® Next Generation Skin Care Products in Turkey

Article in Health Plans Plus concerning AC-11®

(07/20/07) Solgar Vitamin and Herb Enters Into Exclusive Trademark Licensing Agreement with Optigenex Inc.
(07/10/07) Itochu Corporation, Tokyo Enters Into Exclusive Supply and Trademark Licensing Agreement with Optigenex Inc. to Distribute AC-11®
(04/04/07) RFI Ingredients Enters into Exclusive Trademark Licensing Agreement with Optigenex Inc. to Market and Distribute AC-11® to Healthcare Practitioners

Life Extension Enters Into Trademark Agreement with Optigenex Inc. to Market and Distribute AC-11® in a Stand Alone Nutritional Supplement Product

(10/24/06) LifeSpan International Inc. Enters Into Agreement With Optigenex Inc. to Market and Distribute Proprietary Skin Care Products and Supplements
(10/04/06) McGovern Capital LLC Enters Into Exclusive License with Optigenex Inc. for Use of AC-11® in Beverages
(11/16/05) Optigenex's Prometheon Labs Rolls Out New Product Avatar 8 With AC-11® in New York Metro Area
(09/08/05) Optigenex (OPGX) Secures $4 Million Financing Package
(08/11/05) Optigenex Inc, (OPGX) To Feature Presentation On Anti-Aging At Erie County Fair
(08/03/05) Optigenex Inc., An Innovator in Advanced DNA Sciences, Forms Joint Venture With Prometheon Holding, LLC
(07/25/05) Optigenex Inc., a World Leader in Advanced DNA Repair, Promotes AC-11® Anti-Aging Nutritional Supplement on the iVillage Network

Manufacturing in Brazil:


AC-11® is harvested in the Amazon Rainforest and manufactured by Centroflora Group Botucatu, Brazil.                              Centroflora Group Certifications

Centroflora Group was founded in 1957 in the city of São Paulo, and is today the leader in the production and development of standard plant extracts for the drugs, cosmetics and food industries in South America. We seek complete environment sustainability of our raw materials. This goal has been achieved by establishing partnership with small farming communities in order to develop the cultivation of special species as well as the sustainable management of native species.

We are committed to providing innovative and quality solutions and products, with experienced professionals and experts in extraction technology and processes, enabling distinguished, competitive, and often innovative products and processes. Centroflora Group works in partnership with major universities and research institutes in Brazil and abroad, seeking the formation of new specialized human resources, new product development, and the implementation of new technologies to offer our clients. These technologies contribute to continuous enhancement of our professionals, adding science to business, and resulting in the development of a phyto-product network, contributing to the incorporation of new technologies into our manufacturing plants.

Distribution in Japan & Asia:


Optigenex Inc. Signs New License and Distribution Agreement With Itochu Corporation of Japan.
To date, Itochu has introduced AC-11® to over 100 companies in the cosmetic and dietary supplement market, with over 130 products containing AC-11® being marketed and sold. Yusuke Itou of Itochu Corporation added the following, "We are very pleased with the positive reception AC-11® has received from manufacturers in Japan and our expanding role in marketing AC-11® in Southeast Asia. We anticipate strong demand for additional AC-11®-based products in the remainder of 2009 and beyond as consumer awareness of the benefits of AC-11® for healthy DNA maintenance and natural skin collagen production increases." Itochu has approximately 45,690 employees maintains over 130 offices and owns over 651 subsidiaries and affiliates around the world. Itochu's sales last year reached 11.58 trillion yen (U.S. $95 billion). Read Optigenex's press release!

Products being marketed include skin creams, sunscreens, serums, shampoos, supplements and beverages (Acai berry + AC-11®).

                                                            View more Japanese products and advertisements! 

Distribution in the United States & Worldwide:


PhytoRich AC-11®
Energy Management Formula
DNA damage is at the heart of most degenerative maladies as well as the aging process itself. AC-11® is a patented and advanced bioactive formula derived from the South American herb Uncaria tomentosa (Cat’s Claw), which has been traditionally used as a tea by the Indians in the rainforest of South America to enhance the immune system and general health. AC-11® has been clinically proven to reduce both oxidative damage and non-oxidative damage to DNA caused by stress, viruses or bacteria. Clinical studies have also reported reduced inflammation and improved immune function.

  • Helps to decrease DNA damage
  • Supports a decrease in inflammation
  • Improves immune function
  • Increases DNA repair

The LifeMap Nutrition™ System is the first customized nutritional and optimal health system where nutritional supplement ingredients and products are genetically matched to an individual's DNA.

AC-11® is one of the key ingredients in the base product of the GeneWize LifeMap Nutrition™ supplement. GeneWize customers send in the Healthy Aging DNA Assessment and GeneWize custom makes a nutritional supplement based on this DNA assessment. In addition to AC-11®, the GeneWize product contains antioxidants; super fruits such as Acai, Goji, Mangosteen, Pomegranate; resveratrol, green tea, folate, vitamins, and other ingredients important for optimal health. AC-11® can also be found as a separate ingredient at your local health store.
Read Optigenex's press release!

GeneWize Life Sciences, Inc. is a wholly owned subsidiary of GeneLink, Inc.  

RFI Ingredients, based in Blauvelt, NY, is a manufacturer of innovative natural ingredients for the food, functional food and dietary supplement industries. The company, which was formed in 1989, specializes in the supply of quality ingredients (including certified-organic) and proprietary formulations, building on its global partnerships and in-house applications laboratory.

Our extensive network of global partners enables us to offer multiple markets for natural products sourcing, allowing us to capitalize on worldwide seasons and economic fluctuations. With manufacturing operations in North America, South America and China, we can offer true global reach. In addition to our international raw materials sourcing platform, we also operate Atlantic Coast Functional Foods (ACFF), a separate company that concentrates on selling functional foods into the Asian market.
Read Optigenex's press release!


 AC-11® Vegetable Capsules

Solgar introduces AC-11® Vegetable Capsules offering consumers this proprietary, patented, water-soluble extract of Uncaria tomentosa for enhanced care and maintenance of DNA. Kosher certified, this product is also free of yeast, wheat, soy, gluten, and dairy products and is formulated without the use of artificial preservatives, flavors, or colors. 
Read Optigenex's press release!

Solgar has been manufacturing fine quality nutritional supplements for over 60 years in an industry that is constantly evolving. Throughout these changes, we have never lost sight of our original mission - to provide consumers with the highest quality nutritional products and information to help promote optimal health.



The key ingredients in AGEOFF have been clinically proven at 3 major universities including the University of Lund (Sweden), University of Kansas (US), and Osaka City University (Japan). AGEOFF was developed in collaboration with anti-ageing authority Dr. Peter Pugliese and is doctor recommended.

Distribution in Turkey & the Middle East:


Ekson Farma signs on to develope, market and distribute Activar® AC-11® in a triple-play Day Cream, Night Cream and Eye Cream combination. Activar® AC-11® in supplement form is also available. Founded in 1994, Ekson Farma is an applied sciences and marketing company focused on providing wellness solutions and related technologies to physicians, pharmacies and the general medical community.

Ekson's strategy is to select superior and innovative products validated by clinical and scientific studies, establish consumer and physician acceptance through test marketing and ultimately distribute those products with the goal of improving the quality of life for health conscious consumers and patients. Ekson through its collaboration with research partner
OKSANTE LABORATORIES is noted for its development of diagnostic tools utilizing DNA sequencing and molecular diagnostics with an emphasis on early detection of disease and DNA mutations. Read Optigenex's press release!


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#15114   ?????????? To play. They want to buy Yaco 05/14/19 11:47:13 AM
#15113   This could be why - and it could tedpeele 01/06/19 09:04:28 PM
#15112   Not sure what's going on here cause I Justabit 01/04/19 09:02:58 PM
#15111   No news or filings that I can find. Alyssa 01/04/19 02:04:36 PM
#15110   Good Morning. I have had Opgx shares for Yaco 01/02/19 11:27:01 PM
#15109   Why is this trading agian????? tbnfl4sun 03/18/17 09:16:20 AM
#15108   First news in a long time. Did $hellKing 03/24/16 02:38:33 PM
#15107   Optigenex and Life Science Institute Extend International Licensing $hellKing 03/24/16 02:38:07 PM
#15106   Damn! That's a lot of money to put mrlahjr 08/09/15 11:13:41 AM
#15105   That is true. They reversed me down to Investolator 02/12/15 01:35:46 PM
#15104   Yea right. LOL. They burned every shareholder they TEXASOIL 05/27/14 01:58:13 PM
#15103   OPGX is smells like a winner kranthikumar 05/27/14 09:53:01 AM
#15102   They will sell you millions at .0001, then augusthog 10/04/12 12:07:28 PM
#15101   Can Anyone give me a nice recap of FloridaGators1975 09/29/12 04:20:56 AM
#15100   Definitely something is up ... BIG time!! The WhaleWatch 09/20/12 05:41:04 PM
#15099   Up 150% since pre R/S on 600,000 share TEXASOIL 09/20/12 12:08:22 PM
#15098   I have 67 shares left after the split....... augusthog 09/19/12 11:17:22 PM
#15097   Better shape than I am. I have been Luna Tic 09/19/12 03:03:14 PM
#15096   I got 1 share after all the r/s, Elijah875 09/19/12 11:39:20 AM
#15095   .24 is 100% by my math (.0002)! TEXASOIL 09/18/12 07:38:25 PM
#15094   anybody who bought .0001 pre r/s is up koolmc 09/18/12 05:39:08 PM
#15093   Someone is buying up, patiently buying up, a TEXASOIL 09/18/12 09:50:25 AM
#15092   there is a sign of life here who rjfmiranda 09/12/12 05:11:43 PM
#15091   OPGX changed back to OPGXD: Renee 09/06/12 07:14:13 PM
#15090   The “D” will disappear after 20 trading days. Luna Tic 09/06/12 11:34:33 AM
#15089   39,900% increase ROFLMAO Luna Tic 09/05/12 04:17:07 PM
#15088   08:51 9/1/2012 OPGX Optigenex Inc. NEW Common Stock smalltimetrader 08/31/12 10:17:02 AM
#15087   I dont know if its good or bad, batrob 08/01/12 03:21:37 PM
#15086   The dead fish has returned to life! augusthog 07/31/12 08:42:18 PM
#15085   It's a Sicilian message: OPGX sleeps with the fishes....... augusthog 06/23/12 10:34:28 AM
#15084   This things is going to win the shit Phixieus666 09/29/11 04:33:11 PM
#15083   0.0001 again!!!!!! It be 2000 share = 1 soon. Blackfuture 07/25/11 12:56:43 PM
#15082   lucky that i'm out last year before the jsp183 06/03/11 03:20:39 PM
#15081   My My seems to have gone no bid pt1091 06/01/11 03:18:10 PM
#15080   The SEC couldn't have caught Bin Laden pt1091 05/26/11 03:04:24 PM
#15079   This is a solution that is considering the pennywest 05/25/11 07:08:18 PM
#15078   I feel I've invested in a fraud is pennywest 05/25/11 07:05:02 PM
#15077   It's amazing, if you take a gun pt1091 05/25/11 02:55:48 PM
#15076   He dumped enough shares for a nice weekend, pt1091 05/20/11 03:31:51 PM
#15075   Appalling. JPGetty 05/18/11 05:54:04 PM
#15074   60 MM at 0.0001 today? This company is pennywest 05/17/11 05:05:27 PM
#15073   make that 60 million, this is criminal! pt1091 05/17/11 03:42:18 PM
#15072   24 mill dumped at .0001 pt1091 05/17/11 01:35:16 PM
#15071   Sure they do, the only problem is pt1091 05/16/11 02:32:46 PM
#15070   Does OPGX ever release any financial or earning flaw5 05/13/11 05:03:27 PM
#15069   no bid on this scam, SOON! pt1091 05/11/11 03:54:20 PM
#15068   Let's see pt1091 05/11/11 03:53:13 PM
#15067   volume on buying, not selling TheProfit 05/11/11 03:20:54 PM
#15066   KAZAAM!!! Could you provide a little more detail pt1091 05/09/11 11:08:25 AM
#15065   Nope, not yet :-) Druseljic 05/06/11 03:22:11 PM