Moderna Inc (MRNA)

[Vexari]

It did break the blood brain barrior

How does one know this

[axelvento]

This vaccine could drive growth for years if it gets approved:

Merck and Moderna split the costs and profits of the mRNA-4157 program equally, because both contributed their technology and intellectual property to the effort. In fact, it's Merck's best-selling immuno-oncology drug Keytruda that's a key component of most of the personalized cancer vaccine formulations being tested currently. Whereas mRNA-4157 aims to activate the immune system against a tumor, Keytruda protects the cells of the immune system from being hampered by some of the defenses that tumor cells often have.

So good results in the clinic for Moderna are also good results for Merck, and it looks like the pair are cooking up some more bullish results for the future too.

https://finance.yahoo.com/news/1-green-flag-moderna-merck-124500083.html

[axelvento]

in the brain-----

[Vexari]

Fighting over death patents

While genocide

Plays its role

[DewDiligence]

US_district_court pauses MRNA’s patent-infringement suit vs PFE/BNTX pending USPTO input:

https://www.reuters.com/legal/litigation/pfizer-wins-pause-modernas-covid-19-patent-lawsuit-2024-04-12/

Moderna's patent lawsuit claiming Pfizer and BioNTech copied its COVID-19 vaccine technology will be put on hold while the U.S. Patent Office determines whether two of the three Moderna patents at issue are valid, a Massachusetts federal court said on Friday.

U.S. District Judge Richard Stearns stayed the closely watched case over Moderna's objections after determining that the Patent Office's rulings would "simplify" the patent-infringement lawsuit, according to an entry on the court's docket.

[Vexari]

In the veins

What is the difference between

Life

And understanding

[axelvento]

Whiskey$$$$$$

[Vexari]

What was behind them

To which

It propagated

[Vexari]

What is in those vaccines

Towards that future

[axelvento]

HUGE$ head and neck squamous cell carcinoma (HNSCC). Data from the study showed that treatment with the combination not only achieved positive clinical responses in HPV- HNSCC patients but even showed evidence of activation of immune responses. The combined therapy was also found to be safe and well-tolerated by study participants.

Per management, treatment with the combination achieved an objective response rate (ORR) in six out of 22 patients, including two complete responses and four partial ones. The disease control rate was 63.6%. These results were presented at the American Society of Cataract and Refractive Surgery (ASCRS) earlier this week.

[axelvento]

Not only was the combination found to be safe, researchers found evidence that it activated immune responses

https://s29.q4cdn.com/435878511/files/doc_presentations/2024/Apr/08/12091203_aacr2024_bauman_poster_159-76x94-76_v22_final-61.pdf

[axelvento]

vaccine shows benefit in head and neck cancer in early study
Data from 22 patients who received the vaccine, mRNA-4157, in combination with Keytruda was reported at the American Association for Cancer Research Annual Meeting at San Diego on Monday.

The vaccine combination showed evidence of activation of immune responses in patients, and was found to be safe and well tolerated in the study, Moderna said.

[imanjen13]

I

[axelvento]

We can see that institutions own the lion's share in the company with 68% ownership

[axelvento]

next catalyst -The PDUFA (Prescription Drug User Fee Act) action date for mRNA-1345 is May 12, 2024

[axelvento]

Cancer vaccines----- towards a new future

https://www.nature.com/collections/dfajababaj

[starkd748]

I load if 30 comes....They have trial results on herpes coming out June 2025

[Monksdream]

MRNA over $30

[axelvento]

https://www.nasdaq.com/campaign/sponsored/invescoqqq/innovation-answered/?utm_campaign=IA&utm_medium=OrganicSocial&utm_source=Twitter

[axelvento]

Bird flu pandemic could be ‘100 times worse’ than COVID, scientists warn
Around 52% of humans who have contracted H5N1 since 2003 have died, according to the World Health Organization.

https://cdn.who.int/media/docs/default-source/wpro---documents/emergency/surveillance/avian-influenza/ai_20240329.pdf

https://nypost.com/2024/04/04/us-news/bird-flu-pandemic-could-be-100-times-worse-than-covid-scientists-warn/

[Vexari]

Childhood decease is caused

~~~ By the 72 injections before age 18~~~
(1:14)

Watch the FULL interview on CHD TV: https://live.childrenshealthdefense.org/chd-tv/events/

Info that matters

[axelvento]

mRNA drug offers hope for treating a devastating childhood disease

Nassrine Fawaz in Livonia, Michigan, has witnessed a transformation in her 4-year-old daughter, who has received mRNA-3927 for the past 2.5 years. After each infusion, “she’s focused, she’s energetic, she’s up and ready for the day — all of those great things”.

https://www.nature.com/articles/d41586-024-00954-4

[Vexari]

A wave would make

For a good reply

When surfing

In a tsunami

[axelvento]

a judge just came down with a partial decision in Arbutus favor not a ruling, just a decision that strengthens their hand against Moderna

"He ruled in favor of Roivant subsidiary Arbutus on 3 of 4 patent claims...It is our understanding Moderna can't appeal for now since this isn't a formal 'judgment' but rather a 'decision'", Jefferies analysts wrote in a note.

A trial in the case is currently set to begin next April.....

Reuters!

[axelvento]

[Vexari]

Nature is being turned on its head

To make it something

That it is not

[axelvento]

https://finance.yahoo.com/news/phase-1-2-interim-data-150000055.html

[axelvento]

Long Live Pussy$$$$$$$$$$

[Vexari]

What is one trying to say

In one's own words

[axelvento]

https://www.streetinsider.com/Analyst+Comments/Piper+Sandler+Reiterates+Overweight+Rating+on+Moderna+%28MRNA%29/22994831.html?classic=1

[Vexari]

Toothpicks

Are a far better remedy

[Vexari]

On the road again

[axelvento]

Cancer-busting vaccines
Treatments that could train the immune system to identify and destroy cancer cells are on the way.

https://www.nature.com/articles/d41586-024-00842-x

[axelvento]

MIT spinout Strand Therapeutics has developed a new class of mRNA molecules that can sense where they are in the body, for more targeted and powerful treatments.

https://news.mit.edu/2024/strand-therapeutics-unlocks-mrna-cancer-fighting-potential-0327

[axelvento]

many as 15 new products over the coming five years- If Moderna even achieves a small part of that goal, investors could be looking at a new era of revenue growth for the company!

[axelvento]

time will tell-------Cancer-vaccine trials give reasons for optimism

https://www.nature.com/articles/d41586-024-00840-z

[axelvento]

Bancel’s brief interview on China . Moderna is doing a 1 bn manufacturing investment in China , i believe largely subsidized by the Chinese government with approval of US administration. but should be completed in 2026 . China interested by mrna développement opportunities like cancer ect . Covid Moderna vaccine not yet approved for Chinese!!!!!!

[axelvento]

Expects two more Phase 3 readouts in 2024, including combination vaccine against flu and COVID-19, and vaccine against CMV

[Vexari]

All based on the effects of the jab

Making them sick

While making them feel better

By way

Of more drugs

[XenaLives]

Really lame....
Prevention sounds like a better option.

I researched the flu vaccines in the early '90s and will not take them either.

The only vaccine I would consider is tetanus after an injury.

Epstein Barr virus (EBV) is a herpesvirus in which over 90% of the population worldwide has been infected.

https://www.ncbi.nlm.nih.gov/books/NBK559285

AI summary:

Yes, some chemotherapeutic drugs
can cause Epstein-Barr virus (EBV) infection in latently infected cells. These drugs include: Gemcitabine, Doxorubicin, Cis-platinum, and 5-fluorouracil.
EBV
can also be reactivated by drug-induced hypersensitivity syndrome (DRESS), which is a severe reaction to certain drugs. DRESS is characterized by: Fever, Skin eruption, Cervical lymphadenopathy, Leukocytosis with atypical lymphocytosis and/or eosinophilia, and Liver dysfunction.
Anticonvulsants
and antimicrobial agents are some drugs that can cause DRESS. For example, allopurinol and carbamazepine have been associated with EBV reactivation.
Some drugs can also inhibit EBV replication in vitro, including:
Acyclovir, Desiclovir, Ganciclovir, Interferon-alfa, Interferon-gamma, Adenine arabinoside, and Phosphonoacetic acid.

Medscape Reference
Pediatric Mononucleosis and Epstein-Barr Virus Infection ...
3 days ago — Class Summary. Numerous drugs inhibit Epstein-Barr virus replication in vitro. These include acyclovir, desciclovir, ganciclovir, interferon-alfa, interferon-gamma, adenine arabinoside, and phosphonoacetic acid. Acyclovir, which inhibits viral shedding from the oropharynx, is the only antiviral drug used to treat infectious mononucleosis in placebo-controlled clinical trials. However, the clinical course is not significantly affected in patients with uncomplicated infectious mononucleosis.

EBV is best known for causing mononucleosis , but it can also lead to other diseases, including: Ear infections and diarrhea in children
Guillain-Barre syndrome Certain cancers, including Burkitt's lymphoma and cancers of the nose and throat Post-transplant lymphoproliferative disease (PTLD)

This is for informational purposes only. For medical advice or diagnosis, consult a professional.

So if you have a 90% chance of having latent EBV why would you or your physician risk these drugs?

I speak from experience - I was poisoned by Cipro, a fluroquinolone. I died.... and I was given this lethal antibiotic for a FUNGAL INFECTION.

Anticonvulsant Hypersensitivity Syndrome Associated with Epstein-Barr Virus Reactivation
Jae Yong Chang and Soo-Chan Kim corresponding author

We describe a 59-year-old female with severe anticonvulsant hypersensitivity syndrome (AHS) associated with Epstein-Barr virus (EBV) infection. The causative drug was speculated to be carbamazepine. Recurrent EBV infection was demonstrated by the presence of anti-EBV early antigen IgM antibodies and anti-EBV nuclear antigen IgG antibodies. To our knowledge, only one case of drug hypersensitivity syndrome (DHS) associated with EBV has been reported in the English-language literature. Our case is the second report of EBV-associated DHS, which suggests that EBV infection may contribute to the pathogenesis of AHS in a few patients.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628108/

[axelvento]

Moderna's early vaccine pipeline underpinned by Epstein–Barr, norovirus and shingles prospects

https://www.fiercebiotech.com/biotech/modernas-early-vaccine-pipeline-underpinned-three-sets-phase-1-data

[axelvento]

Blackstone Life Sciences Announces Collaboration to Support Moderna’s Influenza Program


https://www.blackstone.com/news/press/blackstone-life-sciences-announces-collaboration-to-support-modernas-influenza-program/

[axelvento]

Moderna's vaccine portfolio targets large addressable markets, with an estimated total addressable market (TAM) of $52 billon for Moderna infectious disease vaccines, which includes a respiratory vaccines TAM of more than $27 billion and a latent and other vaccines TAM of more than $25 billion.

[axelvento]

$MRNA https://www.modernatx.com/en-US/media-center/all-media/blogs/recapping-fifth-annual-vaccines-day

[axelvento]

Moderna Advances Multiple Vaccine Programs to Late-Stage Clinical Trials


https://investors.modernatx.com/news/news-details/2024/Moderna-Advances-Multiple-Vaccine-Programs-to-Late-Stage-Clinical-Trials/default.aspx

[Vexari]

Basically

Increase dosages of poison to the body

To get an even bigger immune response

The more poison

The stronger the response

Beginning to feel like a guinea pig

Question is

How long does that response last

And what immune deficiencies will it bring

Long term

[DewDiligence]

MRNA’s next-gen COVID vaccine produces_stronger immune response_than Spikevax:

https://www.accesswire.com/846784/moderna-achieves-positive-interim-results-from-phase-3-trial-of-next-generation-covid-19-vaccine

The next-gen vaccine, mRNA-1283, also has a longer shelf life and less onerous storage requirements compared to Spikevax.

[Vexari]

What is a vaccine

And

What is it supposed

To do

Think about that

While humankind

Waits

In the wings

[axelvento]

C. Wood is here and continues to add

[axelvento]

The next catalyst would be Moderna’s fifth annual Investor Event focused on vaccines and business updates, due March 27

stay tuned