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Last Post: 4/3/2020 12:16:26 AM - Followers: 607 - Board type: Free - Posts Today: 1




Inovio Selected by CEPI to Develop Vaccine Against New Coronavirus
9:15 AM ET 1/23/20 | PR Newswire

PLYMOUTH MEETING, Pa., Jan. 23, 2020 /PRNewswire/ -- Inovio Pharmaceuticals, Inc. (NASDAQ:INO) today announced the Coalition for Epidemic Preparedness Innovations (CEPI) has awarded Inovio a grant of up to $9 million to develop a vaccine against the recently emerged strain of coronavirus (2019-nCoV) that has killed numerous people and infected hundreds more in China to date. This initial CEPI funding will support Inovio's preclinical and clinical development through Phase 1 human testing of INO-4800, its new coronavirus vaccine matched to the outbreak strain. CEPI previously awarded Inovio a grant of up to $56 million for the development of vaccines against Lassa fever and Middle East Respiratory Syndrome (MERS), also caused by a coronavirus.

Inovio's participation in this developing effort is based on the ideal suitability of its DNA medicine platform to rapidly develop a vaccine against an emerging virus with pandemic potential, proven vaccine development capabilities and a strong track record of rapidly generating promising countermeasures against previous pandemic threats. Inovio was the first to advance its vaccine (INO-4700) against MERS-CoV, a related coronavirus, into evaluation in humans. Inovio is currently preparing to initiate a Phase 2 vaccine trial for INO-4700 in the Middle East where most MERS viral outbreaks have occurred.

In a recently published paper in Lancet Infectious Diseases, Inovio's Phase 1 study of its MERS-CoV vaccine demonstrated it was well tolerated and furthermore induced high levels of antibody responses in roughly 95% of subjects, while also generating broad-based T cell responses in nearly 90% of study participants. Durable antibody responses to INO-4700 were also maintained through 60 weeks following dosing.

Richard Hatchett, CEPI's CEO, said, "Given the rapid global spread of the 2019-nCoV virus the world needs to act quickly and in unity to tackle this disease. Our intention with this work is to leverage our work with Inovio on the MERS coronavirus and rapid response platform to speed up vaccine development."

Dr. J. Joseph Kim, Inovio's President & CEO said, "We're extremely honored to expand our partnership with CEPI to tackle this new threat to global public health. Our DNA medicine platform represents the best modern day approach to combatting emerging pandemics. We have already demonstrated positive clinical outcomes with our vaccine against MERS-CoV, another coronavirus. Importantly, following the Zika viral infection outbreak, Inovio and our partners developed a vaccine that went from bench to human testing in just seven months -- the fastest vaccine development on record in recent decades. We believe we can further improve upon this accelerated timeline to meet the current challenge of the emerging Chinese coronavirus 2019-nCoV."











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#20503  Sticky Note Bill Gates mentions INO on CNN last night Nascarrat 03/27/20 03:10:29 AM
#16710  Sticky Note $INO Inovio Accelerates Timeline for COVID-19 DNA Vaccin $Pistol Pete$ 03/06/20 04:57:29 PM
#15952  Sticky Note Inovio shares rally after biotech says human trials Golden_Cross 03/04/20 02:07:59 AM
#15336  Sticky Note $INO is a company heavily involved in experimenting NEO 00110001 02/11/20 02:21:38 PM
#14894  Sticky Note Inovio has no "vaccine". A vaccine implies something MiamiGent 01/28/20 07:18:32 PM
#4698  Sticky Note Please stay on topic. The only topic to IH Dan (Retired) 08/02/13 01:15:33 PM
#21420   Each of us gets 15 posts a day. AlwaysOptimistic 04/03/20 12:16:26 AM
#21419   Infested with shorters just like yourself. BDEZ 04/02/20 11:50:04 PM
#21418   Shorters continue to litter the INO board 24 hours. BDEZ 04/02/20 11:48:56 PM
#21417   Definition of Research Vaccine Candidates AlwaysOptimistic 04/02/20 11:28:02 PM
#21416   timetravelerdos right. Call Bill Gates. You present yourself AlwaysOptimistic 04/02/20 11:22:29 PM
#21415   Good Grief!!! The DOD doesn’t check DD? Bill timetravelerdos 04/02/20 10:21:00 PM
#21414   So have you called Bill Gates ? Have timetravelerdos 04/02/20 10:16:28 PM
#21413   Agree with INO having the best outcome! blanka 04/02/20 09:11:26 PM
#21412   Did you call Bill Gates ? Did you timetravelerdos 04/02/20 08:54:22 PM
#21411   https://seekingalpha.com/article/4335677-assessing-survival-potential-dave-buste Nascarrat 04/02/20 08:37:10 PM
#21410   I LOVE KARMA ... it comes in all different blanka 04/02/20 08:24:04 PM
#21409   Do you ?!? INO$$$$ StocksNcash 04/02/20 07:46:54 PM
#21408   INO Do you understand the difference between a MiamiGent 04/02/20 07:15:41 PM
#21407   so who is it? Opti Mist 04/02/20 07:14:16 PM
#21406   INO Just out of curiosity, have you read MiamiGent 04/02/20 07:07:08 PM
#21405   Love it time, just a matter of time. BDEZ 04/02/20 06:51:17 PM
#21404   Just shows you the evil in people StocksNcash 04/02/20 06:28:38 PM
#21403   They are looking to sell more shares, there ADXSINC 04/02/20 06:20:25 PM
#21402   It is absolutely unbelievable that some people are timetravelerdos 04/02/20 06:10:58 PM
#21401   Cadi!!! And Wyatt says that there are Nascarrat 04/02/20 06:02:59 PM
#21400   Ian Wyatt webinar $998 vaccine Inovio pick cadillac48 04/02/20 05:42:31 PM
#21399   Oh man my bad lol Hey great post StocksNcash 04/02/20 05:15:47 PM
#21398   There will be many more for you to Nascarrat 04/02/20 05:14:07 PM
#21397   Hey, that was my post! cadillac48 04/02/20 05:10:29 PM
#21396   Awesome thanks for sharing StocksNcash 04/02/20 04:55:12 PM
#21395   This is great! New eyes on this.... Nascarrat 04/02/20 04:44:57 PM
#21394   INO is Awesome! Ask Bill Gates and the timetravelerdos 04/02/20 04:35:19 PM
#21393   Yes sir, holding tight. Should see a nice sharky 04/02/20 04:35:07 PM
#21392   This is looking good maybe for tomorrow, not dinogreeves 04/02/20 04:25:45 PM
#21391   Hold on tight to your INO shares and Apenny 04/02/20 04:21:50 PM
#21390   STOCKGUMSHOE TALKS ABOUT INOVIO cadillac48 04/02/20 04:20:45 PM
#21389   All I can say to the non believers StocksNcash 04/02/20 04:04:27 PM
#21388   Not bad today gay traders. A lot Nascarrat 04/02/20 04:01:10 PM
#21387   Yep! One of two. Nascarrat 04/02/20 03:56:44 PM
#21386   I’ve seen him mess with penny stocks. Nascarrat 04/02/20 03:56:21 PM
#21385   So, is true that this company has a SR_8812 04/02/20 03:55:56 PM
#21384   He’s giving me a lot of great loading Nascarrat 04/02/20 03:55:19 PM
#21383   Big board is pure trash ! Karma StocksNcash 04/02/20 03:54:14 PM
#21382   Intra day dips don't matter, its the proper sharky 04/02/20 03:52:29 PM
#21381   Have fun trying to work after hours covering Nascarrat 04/02/20 03:48:58 PM
#21380   Have you ever heard of CELLECTRA? Check Nascarrat 04/02/20 03:45:48 PM
#21379   And making more money.... Nascarrat 04/02/20 03:43:59 PM
#21378   Don’t you guys get tired of shorting a Nascarrat 04/02/20 03:42:54 PM
#21377   Flippers will realize it’s much easier to hang Nascarrat 04/02/20 03:41:30 PM
#21376   Why don’t you realize what type of company Nascarrat 04/02/20 03:40:45 PM
#21375   Fluff is all the company knows. Tell AWIZ 04/02/20 03:39:18 PM
#21374   I’ll take my chances.. Department of Defense, Gates, Nascarrat 04/02/20 03:39:02 PM
#21373   INO is infested with flippers - that's why bigboard 04/02/20 03:38:38 PM
#21372   Are you serious? Come on now. Nascarrat 04/02/20 03:38:05 PM
#21371   INO is long way from producing real stuff..that's bigboard 04/02/20 03:37:46 PM
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