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Inovio Pharmaceuticals, Inc. (INO)

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Last Post: 11/30/2020 8:49:17 PM - Followers: 679 - Board type: Free - Posts Today: 13

Inovio Selected by CEPI to Develop Vaccine Against New Coronavirus
9:15 AM ET 1/23/20 | PR Newswire

PLYMOUTH MEETING, Pa., Jan. 23, 2020 /PRNewswire/ -- Inovio Pharmaceuticals, Inc. (NASDAQ:INO) today announced the Coalition for Epidemic Preparedness Innovations (CEPI) has awarded Inovio a grant of up to $9 million to develop a vaccine against the recently emerged strain of coronavirus (2019-nCoV) that has killed numerous people and infected hundreds more in China to date. This initial CEPI funding will support Inovio's preclinical and clinical development through Phase 1 human testing of INO-4800, its new coronavirus vaccine matched to the outbreak strain. CEPI previously awarded Inovio a grant of up to $56 million for the development of vaccines against Lassa fever and Middle East Respiratory Syndrome (MERS), also caused by a coronavirus.

Inovio's participation in this developing effort is based on the ideal suitability of its DNA medicine platform to rapidly develop a vaccine against an emerging virus with pandemic potential, proven vaccine development capabilities and a strong track record of rapidly generating promising countermeasures against previous pandemic threats. Inovio was the first to advance its vaccine (INO-4700) against MERS-CoV, a related coronavirus, into evaluation in humans. Inovio is currently preparing to initiate a Phase 2 vaccine trial for INO-4700 in the Middle East where most MERS viral outbreaks have occurred.

In a recently published paper in Lancet Infectious Diseases, Inovio's Phase 1 study of its MERS-CoV vaccine demonstrated it was well tolerated and furthermore induced high levels of antibody responses in roughly 95% of subjects, while also generating broad-based T cell responses in nearly 90% of study participants. Durable antibody responses to INO-4700 were also maintained through 60 weeks following dosing.

Richard Hatchett, CEPI's CEO, said, "Given the rapid global spread of the 2019-nCoV virus the world needs to act quickly and in unity to tackle this disease. Our intention with this work is to leverage our work with Inovio on the MERS coronavirus and rapid response platform to speed up vaccine development."

Dr. J. Joseph Kim, Inovio's President & CEO said, "We're extremely honored to expand our partnership with CEPI to tackle this new threat to global public health. Our DNA medicine platform represents the best modern day approach to combatting emerging pandemics. We have already demonstrated positive clinical outcomes with our vaccine against MERS-CoV, another coronavirus. Importantly, following the Zika viral infection outbreak, Inovio and our partners developed a vaccine that went from bench to human testing in just seven months -- the fastest vaccine development on record in recent decades. We believe we can further improve upon this accelerated timeline to meet the current challenge of the emerging Chinese coronavirus 2019-nCoV."

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#34763  Sticky Note 60 days to stop a pandemic Tamtam 11/28/20 02:39:02 AM
#34469  Sticky Note INO-4800 DNA Coronavirus Vaccine percival77 11/12/20 01:50:20 PM
#14894  Sticky Note Inovio has no "vaccine". A vaccine implies something MiamiGent 01/28/20 07:18:32 PM
#34781   Great post and I agree with you and fishhunter 11/30/20 08:49:17 PM
#34780   Count on the Advancement of DNA Medicine with Lakers_w 11/30/20 05:37:52 PM
#34779   SD-Optimal-Research,LLC-said-INO-will-green-light-start-11/30-COB-or-tomorrow. Recruiting-end-12/15/ Lakers_w 11/30/20 04:42:13 PM
#34778   Thank you Gew59! I missed to read that alwaysthankfull 11/30/20 04:00:38 PM
#34777   FDA gave approval for P2 from this pr gew59 11/30/20 03:22:27 PM
#34776   Exactly Lakers, November is what he said... alwaysthankfull 11/30/20 03:14:30 PM
#34775   mRNA-P1PR-took-4-mos 7/14-11/12. Ino-submitted 7/31, should-be-published-12/2-NEJM Lakers_w 11/30/20 02:14:03 PM
#34774   Think Ben said they were going to start gew59 11/30/20 12:28:06 PM
#34773   What happened to the FDA lifting the partial alwaysthankfull 11/30/20 11:38:24 AM
#34772   We need to shoot up it’s a matter blanka 11/30/20 09:13:40 AM
#34771   That’s from sept shorts are gonna start covering LivinLarge8 11/30/20 08:54:41 AM
#34770   $INO https://citronresearch.com/wp-content/uploads/2020/09/Citron-Comments-on-In SpotOnTrade 11/30/20 07:06:09 AM
#34766   Very nice, clear summary! hitekmastr 11/28/20 11:30:48 AM
#34765   Cadillac 107, thanks for taking the time to desarcmo 11/28/20 10:32:47 AM
#34764   So you are looking for a "smart guy" cadillac107 11/28/20 05:06:41 AM
#34763   60 days to stop a pandemic Tamtam 11/28/20 02:39:02 AM
#34762   Got a question for any smart guys out desarcmo 11/27/20 03:50:49 PM
#34761   * * $INO Video Chart 11-27-2020 * * ClayTrader 11/27/20 01:03:28 PM
#34760   https://media1.giphy.com/media/XKCdA6ERnXp6M/giphy.gif?cid=09f1253249be1c4 blanka 11/27/20 12:58:43 PM
#34759   CEPI funded up to $56M to support Inovio’s Lakers_w 11/27/20 12:42:12 PM
#34755   Advaccine-announced-the completion-of-more-than-200M-yuan-in-Series-B-financing. Lakers_w 11/27/20 10:50:10 AM
#34754   Exactly Lakers w, if INO would only get Opus X 11/27/20 08:25:13 AM
#34753   DNA Vaccine INO-4500 Delivery-for-Lassa-Virus P1 starts 12/7/20 Lakers_w 11/27/20 12:15:23 AM
#34752   Advaccine founder Bin Wang congrated inovio as FDA Lakers_w 11/26/20 05:32:46 PM
#34751   It’d-cost-less-than-$6 (Analysts said about others; DNA vaccine is Lakers_w 11/26/20 03:35:11 PM
#34750   PS: Oops meant Sept 25 versus Feb 25 GMA13 11/26/20 03:32:20 PM
#34749   At-min, Ino-will-PR $20M 400-ppl, $50K/person P2-DoD-funding-as-P2-starts-Mon-11/30. The fund Lakers_w 11/26/20 03:08:47 PM
#34748   Ino-4800 P2: US-measures-B-KillerT-cell-response. China-measures-same-and-B-cell-durability-640-ppl Lakers_w 11/26/20 02:41:04 PM
#34747   RE: FDA revised hold on Ph3 & Peer GMA13 11/26/20 01:36:41 PM
#34746   P1PR-will-likely-be-published-online-in-NEJM-Wed-12/2-submitted-at-July-end,4-months-ago. Now-that-P Lakers_w 11/26/20 01:29:56 PM
#34745   Official-INO-4800-P2-start-in-China-Recruiting-11/27-12/15, 640 ppl, 18-85 yrs o Lakers_w 11/26/20 12:27:41 PM
#34744   It's comical that they released the 90%/70% number RMacchio 11/26/20 11:05:54 AM
#34743   WTF, isn't this why they have a phase Opus X 11/26/20 09:10:06 AM
#34742   The AstraZeneca Covid Vaccine Data Isn't Up to Snuff Lakers_w 11/26/20 03:17:38 AM
#34741   We now have the best evidence yet that Lakers_w 11/25/20 08:23:59 PM
#34740   AstraZeneca-manufacturing-error clouds vaccine study results Lakers_w 11/25/20 07:57:57 PM
#34738   Jim:As-a-potential-trial-participant,I-had-my-clinical-trial-pre-screening-telephone-interview-with- Lakers_w 11/25/20 05:28:11 PM
#34737   How many doses do you think Covax locked LivinLarge8 11/25/20 05:23:26 PM
#34736   Court-Filed-11/5-As-of-6/18-Ino-had-manufacturing-lined-up-for-at-least-500,000-doses (i.e.,half-the Lakers_w 11/25/20 05:10:27 PM
#34735   Thank you Lakers for all of the updates Apenny 11/25/20 04:53:46 PM
#34734   Tito-just-register-to-participate-in/INOVIO-4800 P2/3 trials at-AMR-Miami (305)445-5637. They gave m Lakers_w 11/25/20 04:18:52 PM
#34733   The questions continue to pour in for AstraZeneca Lakers_w 11/25/20 03:22:58 PM
#34732   SK-joins-the-Infectious-Disease-Innovation-Alliance. Contribute-$3M-annually-thru-2022-$6.9M-to-INO- Lakers_w 11/25/20 02:38:26 PM
#34731   The-Republic-of-Korea provides $9M-contribution-to-CEPI-to-advance vaccine devel Lakers_w 11/25/20 02:05:20 PM
#34730   Focusing-on-emerging-markets, COVAXX secures $2.8B in vaccine pre-orders Lakers_w 11/25/20 01:54:48 PM
#34729   Got to agree with you guys. I really Opus X 11/25/20 01:43:50 PM
#34728   Lakers, that is good news, please Do keep Easka 11/25/20 01:00:39 PM
#34727   @DeptofDefense please provide funds for @InovioPharma now! The Lakers_w 11/25/20 12:46:23 AM
#34726   Moderna boss says COVID-19 vaccine not proven to Lakers_w 11/24/20 09:59:34 PM
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