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Hepion Pharmaceuticals, Inc (HEPA)

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Last Post: 12/1/2021 5:19:32 PM - Followers: 93 - Board type: Free - Posts Today: 2


Hepion Pharmaceuticals (Nasdaq: $HEPA) is a clinical stage biopharmaceutical company focused on the development of targeted therapies for liver disease arising from non-alcoholic steatohepatitis (NASH) and chronic hepatitis virus infection (HBV, HCV, HDV).

Hepion announced top line data from the low dose cohort in the Company's Phase 2a ‘AMBITION' clinical trial of CRV431, an oral, once daily novel cyclophilin inhibitor. This Phase 2a study is continuing with the higher dose of 225 mg CRV431, with NASH patient dosing expected to be completed in Q1-2021.In 2021, of the more than 300 million people living with HBV infection, 10.5% (27 million) were aware of their infection. Non-alcoholic Fatty Liver Disease (NAFLD) affects up to 25% of people in the United States. There are currently no medicines that can cure non-alcoholic Fatty Liver Disease effectively. The same can be said with HBV. With the momentum growing around hepatitis B drug discovery research, we are closer than ever to a cure.

Fact: The inflows have been massive the last 2 weeks. Reason why In just 28 days at the low dose, HEPA CRV431 results were as good as what Madrigal's P3 lead NASH drug took 12 weeks to accomplish.

Bottom line The FDA looks for safety first we have the safest NASH drug our efficacy data is better than MDGL & AKRO. there market caps our almost 10x HEPA. Smart savvy biotech investors with deep pockets know this and are accumulating all they can of HEPA at these levels.
One morning we can wake up and see the price has tripled from its 160 market cap. Also they have 120 million in cash burning under 5 million a quarter. Lots of moving parts here. Gilead & Novo in the mix we will see? A new molecule being added to the pipeline. This management team is experienced 100 years total and world renown experts on cyclophilin inhibitors. They brought a FDA approved blockbuster drug to market already.

June 2021 Hepa Biz Presentation

HEPA Tackling Chronic Liver Disease - CRV431 Mechanism of Action


HEPA website

Chairman of the Board, Gary Jacob, is not just a business guy, he's one hell of a biochemist, and you can bet he has a solid grasp of everything that's going on with Hepion.
He's a key player here!

His background goes way beyond what you ordinarily see on the BOD of little R&D biotechs. You might see those with his research background on Scientific Advisory Boards, but they wouldn't have a fraction of the business expertise he's got.
Hepion has the whole package, with this guy!!

Hepion Pharmaceuticals Welcomes Dr. Stephen Harrison to its Scientific Advisory Board

Former Novo Nordisk Executive, Dr. Todd M. Hobbs, Joins Hepion Pharmaceuticals as Chief Medical Officer
Todd Hobbs coming to Hepion. It was published in December. Hobbs' primary focus has always been on diabetes, and I have said many times that there's a blockbuster reason for him leaving his position as Vice President, Chief Medical Officer at Novo Nordisk, a USD 190B global pharmaceutical behemoth, after nearly 17 years there, to come to tiny Hepion.
I believe we'll be hearing about CRV431 in the treatment of diabetes, as it has the highest known potency of any reported cyclophilin inhibitor known, by a wide margin...

Nash Phase 2 & 3 Trials by companies in the space:
AKRO Akero Therapeutics 1.1 Billion Marketcap 240 Million in cash
MDGL Madrigal Pharmaceutical 1.7 Billion Marketcap 300 Million in cash
HEPA Hepion Pharmaceuticals 160 Million market cap 120 million in cash

Currently trading at $2.2 due to a public offering of 44.000.000 shares $2

According to analysts' consensus price target of $80.00, Hepion Pharmaceuticals has a forecasted upside of 3,503.6% from its current price of $2.22.


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HEPA News: Hepion Pharmaceuticals gets FDA fast track designation for CRV431 to treat liver disease 11/30/2021 03:56:16 AM
HEPA News: Current Report Filing (8-k) 11/30/2021 03:10:45 AM
HEPA News: Hepion Pharmaceuticals Receives FDA Fast Track Designation for CRV431 for the Treatment of NASH 11/30/2021 03:00:00 AM
HEPA News: Securities Registration Statement (simplified Form) (s-3/a) 11/19/2021 12:01:33 PM
HEPA News: Hepion Pharma reports anti-cancer activity of CRV431 in a liver cancer study in mice 11/16/2021 04:11:54 AM
#1485  Sticky Note Page S321 Fress 06/24/21 06:06:41 AM
#1902   $HEPA Just so everyone knows that AKRO is StocktraderDK 12/01/21 05:19:32 PM
#1901   Excellent point Giovanni. Companies apply for fast BooDog 12/01/21 07:01:06 AM
#1900   What percentage of fast track drugs get approved? Giovanni 11/30/21 07:56:05 PM
#1899   Robert Foster, PharmD, PhD, Hepion’s CEO, added, “This BooDog 11/30/21 06:11:15 PM
#1898   OK lolol CreampieMafia 11/30/21 04:59:01 PM
#1897   I'm playing more off the technicals with a BooDog 11/30/21 04:58:31 PM
#1896   Thats when the OS was at 12 mil CreampieMafia 11/30/21 04:07:15 PM
#1895   $HEPA: ROTH Capitals Last update was PT of $14 makinezmoney 11/30/21 01:28:01 PM
#1894   In some at $1.17 tw0122 11/30/21 01:23:07 PM
#1893   $HEPA: We shoud be getting an ANALYST upgrade........... makinezmoney 11/30/21 01:11:39 PM
#1892   Ok but theyre not. They are red. LOL CreampieMafia 11/30/21 12:31:45 PM
#1891   1.15 triple bottom. Trip and rips can BooDog 11/30/21 12:21:44 PM
#1890   LETS BREAK 1.15 lolol CreampieMafia 11/30/21 12:16:59 PM
#1889   What you got to say now? Back to CreampieMafia 11/30/21 11:39:27 AM
#1888   Fast track means faster failure and faster short lololol CreampieMafia 11/30/21 10:20:44 AM
#1887   Thanks for reminding me to short CreampieMafia 11/30/21 10:03:12 AM
#1886   LOL WATCH IT DUMP HAHAHA CreampieMafia 11/30/21 10:03:01 AM
#1885   Like I said unfortunately we’re screwed till we’re Ruffieruff 11/30/21 09:57:14 AM
#1882  Restored Watch it dump lol CreampieMafia 11/30/21 08:52:50 AM
#1881   Filled my 1.27's. Go $HEPA!! BooDog 11/30/21 08:41:25 AM
#1880   $HEPA: Sure you did...... We all BELIEVE YOU. makinezmoney 11/30/21 08:32:09 AM
#1879   I already got what i wanted and covered. CreampieMafia 11/30/21 08:30:59 AM
#1878   That’s the problem. These crooks are tough. Lets Ruffieruff 11/30/21 08:29:49 AM
#1876   Target 1.60's - 1'80's (doesn't have to be BooDog 11/30/21 08:23:24 AM
#1875   $HEPA: NASH treatment space is such a difficult SPACE makinezmoney 11/30/21 08:23:03 AM
#1874   $HEPA FDA consider crv431 a drug with excellent StocktraderDK 11/30/21 08:22:19 AM
#1873   $HEPA (+13.9% pre) Could easy go 50-100% today!!! StocktraderDK 11/30/21 08:21:45 AM
#1872   Lets toast the criminals and move this up StocktraderDK 11/30/21 08:21:14 AM
#1871   Fast Track! Yesssss!!! This just made us F'n rich mpunklil 11/30/21 08:19:49 AM
#1870   $HEPA , Fast track is GOOD news.. StocktraderDK 11/30/21 08:19:14 AM
#1869   $HEPA: FINAALLLYYYYYYYYYYYYYY............. its about DAMN TIME !!!!!!!!!!! makinezmoney 11/30/21 08:18:42 AM
#1868   $HEPA news.... StocktraderDK 11/30/21 08:16:25 AM
#1867   $HEPA load the boat we are ready to StocktraderDK 11/30/21 08:10:34 AM
#1866   Hepion Pharmaceuticals Receives FDA Fast Track Designation for StocktraderDK 11/30/21 08:09:35 AM
#1865   LOL ok you hold CreampieMafia 11/26/21 06:23:49 PM
#1864   Just hold and add. I think it will StocktraderDK 11/23/21 01:50:43 AM
#1863   Dilution in effect CreampieMafia 11/22/21 11:33:30 AM
#1862   This is turning into a major dumpster fire. Ruffieruff 11/22/21 11:01:25 AM
#1861   Added yesterday @1.37, today tried to ad @1.28 Esa 11/18/21 04:02:48 PM
#1860   Added @ $1.31 my. Avg is now $1.90 :) StocktraderDK 11/18/21 02:46:20 PM
#1859   Straight up dumpster fire CreampieMafia 11/18/21 01:14:34 PM
#1858   Waiting for the big dump to sub 1 CreampieMafia 11/18/21 11:17:16 AM
#1857   1.29 ugh lmaoooo hahahahahhaha! CreampieMafia 11/18/21 11:10:30 AM
#1856   1.33 hell yea how low can we go! CreampieMafia 11/18/21 10:07:17 AM
#1855   Lol 1.34 new low. CreampieMafia 11/18/21 10:05:32 AM
#1854   1.3s will be the new norm til it CreampieMafia 11/17/21 04:01:20 PM
#1853   I didnt fail anything. This is in the CreampieMafia 11/16/21 11:29:12 PM
#1852   $HEPA: You failed to get the jist of makinezmoney 11/16/21 02:11:54 PM
#1851   This isnt sava lol CreampieMafia 11/16/21 02:09:54 PM
#1850   $HEPA: Right now is where you load............ makinezmoney 11/16/21 12:52:13 PM
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