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GT Biopharma Inc. (GTBP)

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Last Post: 5/15/2019 1:50:51 PM - Followers: 172 - Board type: Free - Posts Today: 0


The Scourge of Cancer

Cancer is the second leading cause of death globally, and responsible for 8.8 million deaths annually.  The economic impact of cancer is increasing. The total annual economic cost of cancer in 2015 was estimated at approximately US$ 2.5 trillion.  Immuno Oncology sits on the leading edge of cancer treatment and research.  In terms of effectiveness it promises to drastically outpace all previous forms of conventional cancer therapy.  Some estimate the Immuno Oncology market at $US 40 Billon and growing.

What is Immuno Oncology?

Immuno Oncology is treatment that recruits and supercharges a person's own immune system components to fight cancer. This can take various forms: the immune system can be stimulated to work harder or smarter in attacking cancer cells, immune system components can be supplied such as man-made immune proteins that attack cancer cells in a targeted way, immune system cells can be "programmed" to only attack very specific cancer cells or even to deliver a "payload" of compounds poisonous to cancer directly and only to the malignant cells. 


Immuno Oncology Goes Beyond Drawbacks of Conventional Chemotherapy
Conventional chemotherapy poisons the patient's body with the aim of getting the cancer too. Its like spraying a powerful herbicide on your rose garden to get rid of the dandelions. Yes, the weeds will die but the roses will suffer too.

With Immuno Oncology, the cure is not worse than the disease. Many of the harsh and debilitating side effects of chemotherapy are avoided because the agents that kill the cancer are components of the human immune system itself, rather than poison, and the therapy can be precisely targeted to only attack the cancerous cells.  It is truly the next evolutionary leap in cancer treatment.   

GT Biopharma Portfolio

GTBP Therapy Pipeline Highlights

OXS-1550: Treating Lymphoma and Leukemia
When OXS-1550 binds to cancer cells, the cancer cells internalize OXS-1550, and are killed due to the action of drug’s cytotoxic diphtheria toxin payload.  OXS-1550 has demonstrated success in a Phase 1 human clinical trial in patients with relapsed/refractory B-cell lymphoma or leukemia.

The initial phase 1 study enrolled 25 patients (who) received at least a single course of therapy. The treatment at the higher doses produced objective tumor responses with one patient in continuous partial remission and the second in complete remission. Data from ongoing phase 2 expected in 2H ‘18.

OXS-3550: Treating Leukemia
The OXS-3550 IND will focus on AML, the most common form of adult leukemia with 21,000 new cases expected in 2017 alone (American Cancer Society). These patients will require frontline therapy, usually chemotherapy including cytarabine and an anthracycline, a therapy that has not changed in over 40 years.

OXS-1615 AND OXS-C3550: Treating Solid Tumors
This TetraKE is designed to kill not only the heterogeneous population of cancer cells found in solid tumors but also kill the cancer stem cells that are typically responsible for recurrences.

Other Offerings: Central Nervous System Therapies

GTP-011: Motion Sickness Treatment

GTP-011 is a 72-hour patch for which a patent application has been filed by GTP for the prevention of motion sickness, a well-known syndrome that typically involves nausea and vomiting in otherwise healthy people and that occurs upon exposure to certain types of motion.

PainBrake: Treating Neuropathic Pain 
PainBrake® is a new patented formulation of carbamazepine (Tegretol®) that enables accurate dose fractionation for the treatment of neuropathic pain.  An NIH-supported study estimated that almost 16 million Americans suffer from chronic neuropathic pain. Current drugs provide a useful degree of pain relief in only about half the patients. 

GTP-004: Treating Myasthenia Gravis
GTP-004 is a fixed-dose combination tablet for the treatment of myasthenia gravis. Myasthenia gravis is a chronic autoimmune disease of the neuromuscular junction characterized by muscle weakness. The prevalence of the disease in the United States is estimated at 14 to 20 per 100,000 population, approximately 36,000 to 60,000 cases in the U.S. 


GT Biopharma Executive Team: A Who's Who Of The Biotech Sector

"Look at Where Deutsche Bank’s Shawn Cross, Pfizer’s Dr. Raymond Urbanski, Chase Pharmaceutical’s Dr. Kathleen Clarence-Smith, and Barker Davis Founder Geoffrey Davis are making their bets.  Some of the biotech sector’s most affluent and influential individuals are making a move... to GT Biopharma Inc. (GTBP). This up-and-coming biotech company has a therapy pipeline that has attracted some of the industry’s most experienced leaders."


Company Website

GTBP Investor's Overview


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GTBP News: Current Report Filing (8-k) 05/24/2019 06:16:01 AM
GTBP News: Quarterly Report (10-q) 05/15/2019 04:03:42 PM
GTBP News: Current Report Filing (8-k) 04/19/2019 04:24:20 PM
GTBP News: Current Report Filing (8-k) 04/05/2019 04:36:27 PM
GTBP News: Annual Report (10-k) 03/29/2019 04:18:18 PM
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#9588  Sticky Note The topic of this board is OXIS. The CashBowski 03/31/17 11:03:34 AM
#17947   thanks CashBowski. reply appreciated. hopefully we hear something europa7 05/15/19 01:50:51 PM
#17946   Unfortunately I have no details. CashBowski 05/15/19 01:10:45 PM
#17945   800 number goes to a virtual office in europa7 05/15/19 11:35:11 AM
#17944   There was no mention of changing HQ in CashBowski 05/15/19 10:13:43 AM
#17943   GTBP no longer at address? where did europa7 05/09/19 02:02:42 PM
#17942   They better have some surprises other than the stockstalk09 05/05/19 03:42:49 PM
#17941   Let’s see what happens Tuesday when they give Alaskadug 05/05/19 10:51:49 AM
#17939   Oh my, GTBP closed up 8.75% to $.41... Stock62 05/02/19 09:53:14 PM
#17937   This stock really needs to get rid of stockstalk09 05/02/19 02:52:17 PM
#17936   Looks like smart money loading up today for stockstalk09 05/02/19 11:41:17 AM
#17935   Wow Ab )I o) biotech company,up huge over stockstalk09 05/01/19 11:07:07 AM
#17934   Same BS just a different day, with the stockstalk09 04/30/19 10:34:26 AM
#17933   You can list lots of stocks which rocketed, hondaboost 04/29/19 10:39:49 AM
#17926   Wrong, Selling @ 1.00 This Time around promise!! ALL-IN888 04/29/19 10:12:01 AM
#17925   Looks like you bought at 0.39-0.40 and will hondaboost 04/29/19 10:10:10 AM
#17924   A break above the .43 resistance Channel, Panic ALL-IN888 04/29/19 09:48:40 AM
#17923   Back All IN @ .39 - .40 Pushing ALL-IN888 04/29/19 09:43:26 AM
#17922   The converting prices are at $0.60 per share, hondaboost 04/28/19 10:49:58 PM
#17921   Yup I would really like for that to stockstalk09 04/28/19 10:39:34 PM
#17920   If it starts flying, he'll chase it at hondaboost 04/28/19 10:24:02 PM
#17919   I am really big into using charts and stockstalk09 04/28/19 09:26:47 PM
#17918   With more of the right kind of news, stockstalk09 04/28/19 09:17:08 PM
#17917   GTBP, from $7.88 to $2.88 to $0.38, Those hondaboost 04/28/19 09:11:11 PM
#17916   Wow! GTBP, was high as $2.88 in 2018, hondaboost 04/27/19 11:31:00 AM
#17915   Yeah I always sell when the technical bounces ALL-IN888 04/27/19 10:20:21 AM
#17914   Unloaded 100K shares @ .40 Exit from .35 ALL-IN888 04/27/19 10:15:14 AM
#17913   Brainless end of week A hole sellers, who stockstalk09 04/26/19 03:59:34 PM
#17912   Smart money getting in now that the fliptards stockstalk09 04/26/19 02:11:06 PM
#17911   stock manipulator ALL-IN888 put on IGNORE. europa7 04/26/19 02:04:39 PM
#17910   Loaded 100K @ .35 Lets Go back to ALL-IN888 04/26/19 01:33:38 PM
#17909   I just got some for .34. Maybe they Alaskadug 04/25/19 01:55:11 PM
#17908   Investank...very interesting europa7 04/25/19 01:53:30 PM
#17907   2.3 Million Dilution WOW! ALL-IN888 04/25/19 01:43:58 PM
#17906   Round 2 Taking shape $$$$, Fibonacci Traders loading ALL-IN888 04/25/19 12:05:01 PM
#17905   Its Basic Trading the lower range of the ALL-IN888 04/25/19 11:50:42 AM
#17904   It seems to look like there were a stockstalk09 04/25/19 11:46:21 AM
#17903   We should Bounce back to .50 from .361 ALL-IN888 04/25/19 11:19:23 AM
#17902   I knew that once it gets to .60 ALL-IN888 04/25/19 11:17:08 AM
#17901   I added as well. Although this companies Alaskadug 04/25/19 11:00:49 AM
#17900   WOW, Added @ .39 The Bulk of my ALL-IN888 04/25/19 10:52:58 AM
#17899   Touched .44 Support Reloaded @ .45 ALL IN ALL-IN888 04/25/19 10:04:08 AM
#17898   More positive news out this morning announcing they stockstalk09 04/25/19 09:24:01 AM
#17897   Size of gap will tell size of story JaymacsPicks 04/24/19 07:25:16 PM
#17896   Real news on a real platform from a JaymacsPicks 04/24/19 07:23:22 PM
#17895   When news came out this morning, no one eageleye 04/24/19 05:21:02 PM
#17894   https://investorshub.advfn.com/boards/read_msg.aspx?message_id=148419003 [SMART MONEY] 04/24/19 04:25:37 PM
#17893   3,000,000 in volume vs 90,000 average is unbelievable! Alaskadug 04/24/19 04:18:55 PM
#17892   I have been watching and playing this one Alaskadug 04/24/19 04:16:18 PM
#17891   Go read the 'news' again! It's actually Nothing hondaboost 04/24/19 04:11:28 PM
#17890   GTBP, did Huge Reverse Splits, here: hondaboost 04/24/19 03:59:20 PM