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BriaCell Therapeutics (bctxf)

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Last Post: 3/14/2018 12:24:57 PM - Followers: 3 - Board type: Free - Posts Today: 0

About BriaCell

Dedicated to enhance the lives of cancer patients who are facing limited therapeutic options, BriaCell Therapeutics Corp. (OTCQB: BCTXF; TSX: BCT.V)’s mission has been to develop novel immunotherapies, as the most cutting edge technology to fight cancer. Immunotherapies have become the forefront of the cancer treatments because they use the body’s immune system to destroy the cancer cells, offering higher levels of safety and efficacy than chemotherapy, with less likeliness of recurrence.

Designed by our team of scientists and clinicians, BriaCell’s proprietary whole-cell based vaccine technology platform continues to show its impressive potential to establish a new model for treating cancer patients. Our lead product candidate, Bria-IMT™ (SV-BR-1-GM), is a genetically engineered whole-cell vaccine derived from a human breast cancer cell line. Bria-IMT™ is used in combination with multiple immune-modulators to powerfully trigger the immune system to recognize and eliminate cancerous cells.

In a preliminary Phase I clinical study in metastatic (i.e., Stage IV) breast cancer patients who had failed multiple treatments, Bria-IMT™ treatment significantly reduced the tumor size, without serious side effects. Importantly, the tumor regression was observed in other sites including the lung and even the brain -a difficult site. Impressively, the median lifespan of the patients was substantially longer than that of the comparable trials.

At our laboratory facility in Berkeley, CA, we are planning to expand our pipeline of oncology immunotherapy candidates using our proprietary technology platform.

Using the clinical data from the patients from the clinical studies, we are working to identify the molecular fingerprint of the patients for which the vaccine would be highly effective, and are planning to develop diagnostic testing products to identify this group. By directing the drug to the top-responders, we expect this approach to increase the likelihood of clinical trial success of Bria-IMT™ -to bring hope to thousands of cancer patients with few-to-no treatment options.

The company is currently recruiting its Phase I/IIa trial to further test Bria-IMT™ safety and activity in metastatic breast cancer patients. BriaCell maintains global rights for Bria-IMT™.

Phase I/IIa Clinical Study of Bria-IMT™ in Advanced Breast Cancer

BriaCell is currently recruiting patients to evaluate the safety and activity of Bria-IMT™ in an additional Phase I/IIa study in 25-40 metastatic breast cancer patients who have failed at least one course of treatment.

For the details of the trial, please visit For the details of the trial, please visit

Roll-Over Combination Therapy Study

FDA has approved the roll-over combination study of Bria-IMT™ with pembrolizumab (Keytruda; manufactured by Merck & Co., Inc.) or ipilimumab (Yervoy; manufactured by Bristol-Myers Squibb Company) for patients previously treated with BriaVax™ from the ongoing Phase I/IIa Clinical Trial in Advanced Breast Cancer. The study is available for patents on the SV-BR-1-GM Phase I/IIa study who develop progressive disease. These patients will be eligible to roll-over into combination therapy with Keytruda or Yervoy, depending on the type of breast cancer they have.

More information on the roll-over combination study of Bria-IMT™ with either ipilimumab or pembrolizumab will be available on (

KEYTRUDA® (pembrolizumab)

Manufactured by Merck & Co., Inc., KEYTRUDA® (pembrolizumab) is a prescription medicine that may treat certain cancers by working with the immune system. It has been approved for the treatment of a number of cancer indications excluding breast cancer.

For more information on pembrolizumab, please see:

About YERVOY® (ipilimumab)

Manufactured by Bristol-Myers Squibb Company, YERVOY® (ipilimumab) is a prescription medicine used in adults and children 12 years and older to treat melanoma (a kind of skin cancer) that has spread (metastatic) or cannot be removed by surgery (unresectable). It is a monoclonal antibody that works to activate the immune system and enabling them to recognize and destroy cancer cells.

For more informations on Ipilimumab, please see:


Clinical Development Timeline – Breast Cancer

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#33  Sticky Note BriaCell currently is enrolling patients in two separate CREEP 03/06/18 11:57:40 AM
#36   BriaCell Appoints Top Social Media Marketing Analyst CREEP 03/14/18 12:24:57 PM
#35   BriaCell Announces Proposed Investment by Leading Biotech Funds CREEP 03/09/18 09:50:55 AM
#34   BriaCell to Present At 2018 ROTH Conference CREEP 03/09/18 09:46:03 AM
#33   BriaCell currently is enrolling patients in two separate CREEP 03/06/18 11:57:40 AM
#32   BriaCell Therapeutics Corp. ("BriaCell") (TSX-V:BCT) (OTCQB:BCTXF), an immuno-on CREEP 03/01/18 09:20:15 AM
#31   BriaCell Therapeutics Corp. ("BriaCell") (TSX-V:BCT) (OTCQB:BCTXF), an immuno-on CREEP 02/06/18 11:49:17 AM
#30   riaCell Therapeutics Corp. ("BriaCell") (TSX-V:BCT) (OTCQB:BCTXF), an immuno-onc CREEP 02/05/18 03:01:26 PM
#29   BriaCell Therapeutics Corp. ("BriaCell") (TSX-V:BCT) (OTCQB:BCTXF), an immuno-on CREEP 01/04/18 05:39:17 PM
#28   One of the best ground floor bios you GimmeWater 05/13/17 05:42:32 PM
#27   First patient has been dosed. Astrodamus7 05/12/17 01:18:39 AM
#26   Great post, thank you! GimmeWater 04/23/17 07:52:02 PM
#24   Briacell CEO is helping fund the trial with GimmeWater 03/21/17 12:54:43 PM
#23   Trial Underway! GimmeWater 03/21/17 12:53:32 PM
#22   Look at this management team! This is GimmeWater 03/15/17 10:11:06 AM
#21   Main focus of this early trial is safety, GimmeWater 03/15/17 10:05:40 AM
#20   The Phase I/IIa clinical trial is an open-label GimmeWater 03/15/17 10:03:42 AM
#19   BriaCell Receives FDA Clearance to Initiate Phase I/IIa GimmeWater 03/15/17 10:00:30 AM
#18   I am absolutely loading the boat on this GimmeWater 03/11/17 03:36:37 PM
#17   Recent News - BriaCell Files New Patent Application Astrodamus7 03/09/17 01:41:49 AM
#16   Dr. William Williams, President and CEO, has entered Astrodamus7 02/28/17 03:43:18 AM
#15   Positive update on Sept.22 regarding Briacell from BioNap Inc. Astrodamus7 09/24/16 07:18:41 PM
#14   Great risks and Great rewards ! Astrodamus7 09/17/16 03:29:01 AM
#13   Information regarding Phase I/IIa trial Astrodamus7 07/13/16 06:20:44 PM
#12   Preparing to launch Phase I/II this quarter. GimmeWater 04/25/16 05:05:11 PM
#11   thanks for the info..more people on the board raptors1994 04/04/16 04:13:51 PM
#10   has consistently come down on low volume since raptors1994 04/04/16 04:02:58 PM
#9   BriaCell Discovers Gene Signature of BriaVax(TM) Cancer Vaccine Astrodamus7 03/29/16 07:55:21 PM
#8   I love this company! Tried posting over GimmeWater 02/15/16 08:51:15 PM
#7   Here is another interview from The Life Sciences Astrodamus7 12/19/15 12:18:17 AM
#6   BriaCell Therapeutics to Present at 14th Annual BIO Astrodamus7 10/19/15 06:10:53 PM
#5   Primary Symbol: V.BCT Astrodamus7 10/06/15 01:24:44 PM
#4   Special Report from Streetwise Reports. Astrodamus7 10/01/15 03:39:05 AM
#3   All investments carry some degree of risk. The Astrodamus7 09/22/15 06:43:11 PM
#2   This is the lowest price Immuno-Oncology stock with Astrodamus7 09/20/15 09:44:50 PM
#1   An Odd Couple's Corporate Fix for Cancer CREEP 04/16/15 11:04:00 AM