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AngioGenex, Inc. (AGGX)

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Last Post: 12/5/2017 3:21:53 PM - Followers: 7 - Board type: Free - Posts Today: 0

Developing a novel, patented anti-cancer agent that also may be effective treating age related macular generation, rheumatoid arthritis and some symptoms of diabetes. 
Their lead researcher's lab is at Memorial Sloan Kettering. Robert Benezra PhD.
MSK and Benezra are also investors/shareholders.

AGGX has patented technology here 
"Uncovering new functions of a gene implicated in cancer growth opens new therapeutic possibilities 
Date: April 29, 2015 
Source: Weill Cornell Medical College 
Summary: For the first time, researchers have shown that a gene previously implicated in blood vessel formation during embryonic development and tumor growth also induces immune suppression during tumor development. This finding opens the door for new therapeutic approaches and vaccine development in treating patients with melanoma and other advanced-staged cancers." 


AngioGenex is a biopharmaceutical company formed to pursue the discovery and development of proprietary products for the treatment, diagnosis and prognosis of cancer. While there are numerous companies that have the same objective, none have the unique, patented technology that is being exploited by AngioGenex. 
The target of the AngioGenex drug discovery effort is a previously unrecognized biological process necessary to support tumor growth that emerged from one of the most famous cancer laboratories, Memorial Sloan Kettering Cancer Center, NYC. Dr. Robert Benezra, a distinguished member of this institute, discovered that certain genes (Id genes) are actively involved in fetal growth and can be inappropriately activated in the adult to support the growth and spread of tumors. He showed that tumor growth is markedly inhibited if these genes or their proteins are even partially inactivated. 
In collaboration with Dr. Benezra, AngioGenex has successfully pursued the discovery and development of molecules that inhibit the Id proteins and block tumor growth in animals. This research confirms that the Id genes are the controlling, master genes, in a unique and previously unknown process that is required for the growth and spread of tumors. A profound inhibition of tumor growth is demonstrated in animals that either have the Id genes deleted by genetic manipulation or are treated with an anti-Id drug (See Figure below). 
An important finding is that the Id genes are structurally almost identical in humans as in animals suggesting that the anti-tumor effects of Id drug observed in animals will also occur in humans. 



A/S is 150,000,000 Last known outstanding 21,302,906 as of 11/27/2009 (likely more now)

The Robert Benezra lab at Memorial Sloan Kettering


Recent deal with The Trout Group for awareness and funding

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AGGX News: Quarterly Report (10-q) 05/20/2019 05:28:42 PM
AGGX News: Notification That Quarterly Report Will Be Submitted Late (nt 10-q) 05/15/2019 05:01:31 PM
AGGX News: Proxy Statement (definitive) (def 14a) 04/01/2019 12:59:30 PM
AGGX News: Annual Report (10-k) 03/28/2019 04:50:33 PM
AGGX News: Statement of Changes in Beneficial Ownership (4) 02/04/2019 05:24:35 PM
#97   AGGX .28 x .45 Website up after almost e-ore 12/05/17 03:21:53 PM
#96   Looks like they want to do it themselves, e-ore 07/11/17 07:27:50 PM
#95   Stranger things have happened, I do think AGGX protagonist12 07/11/17 07:13:02 PM
#94   They filed a Form 10. They're obligated to e-ore 07/11/17 04:03:23 PM
#93   Okay so I asked DD. You are correct protagonist12 07/11/17 03:40:43 PM
#92   Okay, e-ore let's bring this to DD board. protagonist12 07/11/17 06:40:24 AM
#91   "A Form 10 registration statement automatically becomes effective e-ore 07/11/17 06:39:19 AM
#90   "Upon effectiveness" key words. Very unlikely. Now I protagonist12 07/11/17 06:38:14 AM
#89   haha protagonist12 07/11/17 06:37:03 AM
#88   You need to stop stating your opinion as db7 07/11/17 06:35:40 AM
#87   "Upon effectiveness the Company which filed the Form e-ore 07/11/17 06:15:01 AM
#86   Thanks for that, nice find. I misspoke that protagonist12 07/11/17 12:00:22 AM
#85   Here's another one that happened today. ECMT. Very e-ore 07/10/17 03:18:42 PM
#84   Hey I'm not saying it's not possible for protagonist12 06/28/17 05:52:51 PM
#83   I'll see if anyone can provide examples. db7 06/28/17 05:46:04 PM
#82   Form 15 is a one way ticket to protagonist12 06/28/17 05:43:00 PM
#81   I asked 2 people that I know to db7 06/28/17 05:40:23 PM
#80   Ok can you name one? Believe what you protagonist12 06/28/17 05:38:57 PM
#79   I do not believe this statement to be db7 06/28/17 05:36:19 PM
#78   We will see how far it goes. It protagonist12 06/28/17 05:15:11 PM
#77   The first step to a return to being e-ore 06/28/17 02:38:12 PM
#76   They are trying to register shares? They're a protagonist12 06/28/17 01:54:07 PM
#75   10-12g out, excerpt: "At March 31, 2017, we db7 06/28/17 09:42:58 AM
#74   Yes. That was last June. I remember seeing e-ore 05/23/17 07:15:24 PM
#73   our CEO as mod of this vid(?) db7 05/23/17 04:20:11 PM
#72   Nice grab. eom. Golf4Food 05/01/17 10:11:11 PM
#71   hmmm e-ore 04/17/17 02:51:31 PM
#70   who.is showing changes to angiogenex.com 4/11/17 and 4/17/17 e-ore 04/17/17 10:15:40 AM
#69   I've always hoped they'd start filing again. Technology e-ore 04/11/17 04:13:06 PM
#68   1st SEC filing in 7 years.. I'm guessing db7 04/11/17 03:54:38 PM
#67   Yes, lots of risk here. e-ore 08/03/16 07:50:41 AM
#66   Yeah but it's a form 15 filer. What protagonist12 08/03/16 07:33:36 AM
#65   As usual with me it's about the "what e-ore 08/02/16 07:42:16 AM
#63   I don't know e-ore still just a Form protagonist12 08/02/16 03:57:05 AM
#62   They haven't filed anything but have put out e-ore 07/31/16 04:59:34 PM
#61   Interesting stawk here... would be nice to see Golf4Food 07/31/16 02:52:26 PM
#60   About $50,000 worth of trading in the last e-ore 07/25/16 03:09:10 PM
#59   .55 a buying point if you still believe e-ore 07/21/16 02:07:25 PM
#58   New to the board, say hello to everyone. lifeisagamble 07/18/16 02:41:49 PM
#57   Thanks. Have a good weekend and glty e-ore 07/15/16 03:55:32 PM
#56   beautiful.. don't see enough of these big movers anymore db7 07/15/16 03:32:43 PM
#55   Make it 8, hit .85 e-ore 07/15/16 02:52:44 PM
#54   .80 now. 7th new 52 week high since 6/20 e-ore 07/15/16 01:44:00 PM
#53   Mini volume but another 52 week high. .75 e-ore 07/14/16 01:21:45 PM
#52   Thanks. Glty e-ore 07/12/16 03:32:09 PM
#51   nice job on this one e-ore! db7 07/12/16 03:25:59 PM
#50   10,000 more shares today, now .50 e-ore 07/12/16 03:04:27 PM
#49   5000 shares today so far. Another 52 week e-ore 07/12/16 01:11:45 PM
#48   Only 100 shares but the 4th new 52 e-ore 07/11/16 03:12:55 PM
#47   AGGX filed annual list at Nevada 7/08, was e-ore 07/11/16 08:19:57 AM