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Re: DewDiligence post# 216041

Thursday, 12/14/2017 8:16:02 PM

Thursday, December 14, 2017 8:16:02 PM

Post# of 251280
MDGL. Dew a question for you. Do you know of any drug that RAISES LDL cholesterol , ever being approved by the FDA for a population as large as the NASH population ?
Years ago GSK tries to get Lovaza approved for mixed dyslipidemia ... ( TG's 200-500 ) but the FDA declined and only approved for a very small population of above TG 500 at risk of pancreatitis..

So ICPT's program looks dead on arrival as far as I'm concerned ...as well as any NASH program that raises LDL cholesterol .
Appreciate your thoughts .
Yes ...reversal of liver fibrosis is a high hurdle ...halting progression is worth something

Kiwi

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