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Boom. It really seems like the high TGs

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iwfal Member Profile
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iwfal Member Level  Friday, 10/06/17 12:02:47 AM
Re: tasgrewaf post# 115577
Post # of 116647 
Quote:
Boom. It really seems like the high TGs are the symptom of something else more important going wrong.



I agree that this is probably true - the APOC3 trials by IONS had surprising results on glucose control. Anyone who was paying attention was surprised that something that was expected to only directly influence lipids had a dramatic effect on glucose. (and I give the CEO a lot of credit for really focusing the Ph2s on this - so he'd know.)

And part of the reason I watch AMRN is because I am interested in this nexus - i.e. I will be interested in all the secondary endpoints for the Vascepa ph3.

That said, of course I think the trial has a LOT of risk. In a way very similar to ONTY - I think it likely it has some interesting benefit somewhere, but probably not enough on the primary endpoint (or has enough side effects to cause it not to be worthwhile.).


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